公开(公告)号：US20110309252A1

公开(公告)日：2011-12-22

申请号：US13161904

申请日：2011-06-16

申请人： Kenta MORIYASU ,  Nobutoku MOTOMURA

发明人： Kenta MORIYASU ,  Nobutoku MOTOMURA

IPC分类号： G01T1/164

CPC分类号： A61B6/585 ,  A61B6/037 ,  A61B6/4266 ,  G01T1/1644 ,  G01T1/2985 ,  G01T7/005

摘要： According to one embodiment, a nuclear medicine imaging apparatus includes a detector, a calibrator, and an image reconstruction unit. The detector includes a plurality of detector modules, each counting light originating from a gamma ray. The calibrator unit calibrates time information of all of the plurality of detector modules by calibrating time information for determining each detection time of a pair of detector modules based on each detection time of the pair of the detector modules which approximately coincidentally count annihilation gamma rays and a distance between the pair of detector modules in a state in which a point radiation source including a positron emitting nuclide is installed in each position near a plurality of predetermined detector modules. The image reconstruction unit reconstructs a nuclear medicine image using a time difference between detection times of annihilation gamma rays corrected based on time information calibrated by the calibrator.

摘要翻译： 根据一个实施例，核医学成像装置包括检测器，校准器和图像重建单元。 检测器包括多个检测器模块，每个检测器模块对来自伽马射线的光进行计数。 校准器单元通过校准用于确定一对检测器模块的每个检测时间的时间信息来校准所有多个检测器模块的时间信息，所述检测器模块基于大致巧合地计数湮灭伽马射线的一对检测器模块的每个检测时间，以及 在包括正电子发射核素的点辐射源的状态下，一对检测器模块之间的距离安装在多个预定检测器模块附近的每个位置。 图像重建单元使用由校准器校准的时间信息校正的湮灭伽马射线的检测时间之间的时间差重建核医学图像。

公开(公告)号：US06175118B1

公开(公告)日：2001-01-16

申请号：US09119624

申请日：1998-07-21

申请人： Takuzo Takayama ,  Takashi Ichihara ,  Nobutoku Motomura

发明人： Takuzo Takayama ,  Takashi Ichihara ,  Nobutoku Motomura

IPC分类号： G01T1161

CPC分类号： G01T1/1647 ,  A61B6/037 ,  A61B6/4258 ,  G01T1/1642

摘要： According to the present invention, sub-windows using a TEW technique are centered to energies corresponding to 1/n and 1/m of maximal photon number in a standard energy spectrum without any scattering component. It is thus possible to improve a count coefficiency, while broadening a main window to a maximal possible extent, without underestimating the scattering component and crosstalk component.

摘要翻译： 根据本发明，使用TEW技术的子窗口集中在对应于标准能谱中没有任何散射分量的1 / n和1 / m的最大光子数的能量。 因此，可以提高计数系数，同时将主窗口扩大到最大可能程度，而不会低估散射分量和串扰分量。

公开(公告)号：US5434416A

公开(公告)日：1995-07-18

申请号：US217102

申请日：1994-03-24

申请人： Nobutoku Motomura ,  Takashi Ichihara

发明人： Nobutoku Motomura ,  Takashi Ichihara

IPC分类号： G06T11/00 ,  A61B6/00 ,  G01T1/166 ,  G06F19/00

CPC分类号： G06T11/005 ,  A61B6/037 ,  G06T2211/421

摘要： A method and an apparatus for reconstructing SPECT image capable of improving the SPECT image resolution. The apparatus includes: a detector, including a fan-beam collimator, for detecting gamma (.gamma.) rays emitted from a radio isotope injected into a biological body; a rotation unit for effecting relative rotation between the biological body and the detector about a center of rotation to thereby acquire projection data from a different direction; a first reconstructing unit for convoluting the projection data obtained from the detector, by a first convolution function, and for back-projecting the convoluted projection data to a specific region which lies in a sufficiently close vicinity of the detector; a second reconstructing unit for convoluting the projection data by a second convolution function, and for back-projecting the secondly convoluted projection data to another specific region; and display means for displaying thereon a distribution image reconstructed by the first and second reconstructing units.

摘要翻译： 一种用于重建能够改善SPECT图像分辨率的SPECT图像的方法和装置。 该装置包括：检测器，包括扇形光束准直器，用于检测从注入生物体的放射性同位素发射的伽马射线; 旋转单元，用于围绕旋转中心实现生物体和检测器之间的相对旋转，从而从不同方向获取投影数据; 第一重建单元，用于通过第一卷积函数卷积从所述检测器获得的投影数据，以及将所述卷积投影数据反投影到位于所述检测器的所述特定区域的特定区域; 第二重建单元，用于通过第二卷积函数卷积投影数据，以及用于将第二卷积投影数据反投影到另一特定区域; 以及显示装置，用于在其上显示由第一和第二重建单元重建的分布图像。

公开(公告)号：US09129370B2

公开(公告)日：2015-09-08

申请号：US12704924

申请日：2010-02-12

申请人： Nobutoku Motomura ,  Yasunobu Yamada

发明人： Nobutoku Motomura ,  Yasunobu Yamada

IPC分类号： G06T7/00 ,  A61B6/03

CPC分类号： G06T7/0028 ,  A61B6/037 ,  G06T7/33 ,  G06T2207/10081 ,  G06T2207/10104 ,  G06T2207/10108 ,  G06T2207/30056

摘要： The CT image processor determines the position of the liver in the body of a subject based on CT image. The PET image processor determines the position of the liver in the body of a subject based on PET image. The CT image processor calculates the displacement in the positions of the liver determined by the CT and PET images. The CT image processor extracts the contour of the liver from a CT image. The CT image processor generates a correction CT image by modifying a CT image by moving a CT image to decrease the displacement of the extracted contour in the internal area. The PET image processor performs decrease correction based on the modified CT image.

摘要翻译： CT图像处理器基于CT图像来确定对象体内肝脏的位置。 PET图像处理器基于PET图像来确定对象体内肝脏的位置。 CT图像处理器计算由CT和PET图像确定的肝脏位置的位移。 CT图像处理器从CT图像提取肝脏的轮廓。 CT图像处理器通过移动CT图像来修改CT图像以减小内部区域中提取的轮廓的位移来生成校正CT图像。 PET图像处理器基于经修改的CT图像执行减少校正。

公开(公告)号：US20100158336A1

公开(公告)日：2010-06-24

申请号：US12635045

申请日：2009-12-10

申请人： Nobutoku MOTOMURA ,  Akiyoshi Kinda

发明人： Nobutoku MOTOMURA ,  Akiyoshi Kinda

IPC分类号： G06K9/00

CPC分类号： A61B6/032 ,  A61B6/037 ,  A61B6/5235 ,  A61B6/583 ,  G01T1/00 ,  G06T11/005

摘要： A detector detects gamma-rays emitted from inside an imaging region. An acquisition unit acquires a plurality of first projection data sets associated with a plurality of projection angles via the detector. An attenuation-correction unit attenuation-correct the plurality of first projection data sets based on a first CT image associated with the imaging region to generate a plurality of second projection data sets associated with the plurality of projection angles. An index calculation unit calculates an index based on the plurality of second projection data sets. The index is corresponding to a degree of positional offset between the imaging region at the time of acquisition of a plurality of third projection data sets associated with the first CT image and the imaging region at the time of acquisition of the plurality of first projection data sets.

摘要翻译： 检测器检测从成像区域内发射的伽马射线。 采集单元通过检测器获取与多个投影角度相关联的多个第一投影数据集。 衰减校正单元基于与成像区域相关联的第一CT图像衰减校正多个第一投影数据集，以生成与多个投影角度相关联的多个第二投影数据集。 索引计算单元基于多个第二投影数据集计算索引。 该索引对应于在获取多个第一投影数据集时获取与第一CT图像相关联的多个第三投影数据集和成像区域之间的成像区域之间的位置偏移程度 。

公开(公告)号：US07720518B2

公开(公告)日：2010-05-18

申请号：US11020280

申请日：2004-12-27

申请人： Nobutoku Motomura ,  Masuo Hayashi ,  Syouji Horiuchi ,  Yoshifumi Nisawa

发明人： Nobutoku Motomura ,  Masuo Hayashi ,  Syouji Horiuchi ,  Yoshifumi Nisawa

IPC分类号： A61B5/05

CPC分类号： A61B6/541 ,  A61B6/037 ,  G06F19/00

摘要： A nuclear medical diagnostic equipment wherein radiation which is emitted by a nuclide administered into the body of a patient is detected as projection data by a gamma camera, and an image which indicates the distribution of the nuclide within the body of the patient is obtained on the basis of the projection data. The equipment comprises a rotation unit which rotates the radiation detector round the patient, a respiration identification unit which identifies breathing of the patient and non-breathing thereof based on breath holding, a data storage unit in which the radiation detection data acquired by the radiation detector are stored in an identifiable manner on the basis of a result of the identification by the respiration identification unit, and an image generation unit which generates the image from the radiation detection data stored in the data storage unit on the basis of the result of the identification by the respiration identification unit.

摘要翻译： 核医学诊断设备，其中由被照射到患者体内的核素发射的辐射被伽马照相机检测为投影数据，并且在所述核医学诊断设备上获得指示所述核素在患者体内的分布的图像 投影数据的基础。 该设备包括旋转单元，该旋转单元使患者周围的辐射探测器旋转;呼吸识别单元，其基于呼吸保持识别患者的呼吸和不呼吸;数据存储单元，其中由辐射探测器获取的辐射检测数据 基于呼吸识别单元的识别结果，以可识别的方式存储;以及图像生成单元，其根据识别结果从存储在数据存储单元中的放射线检测数据生成图像 由呼吸识别单元。

公开(公告)号：US08558176B2

公开(公告)日：2013-10-15

申请号：US13152696

申请日：2011-06-03

申请人： Tomoyasu Komori ,  Nobutoku Motomura ,  Takuzo Takayama ,  Atsushi Fukano ,  Masao Yamahana ,  Tatsuya Watanabe

发明人： Tomoyasu Komori ,  Nobutoku Motomura ,  Takuzo Takayama ,  Atsushi Fukano ,  Masao Yamahana ,  Tatsuya Watanabe

IPC分类号： G01T1/00

CPC分类号： A61B6/037 ,  A61B6/032 ,  A61B6/4417 ,  G06T11/006 ,  G06T2211/421 ,  G06T2211/424

摘要： In a nuclear medicine imaging apparatus as a medical image diagnosis apparatus according to one embodiment, a PET detector is configured to detect a gamma ray emitted from a nuclide introduced into a body of a subject. A PET image reconstruction unit is configured to reconstruct a nuclear medicine image (PET image) as a medical image from the gamma ray projection data created based on the gamma ray detected by the PET detector using successive approximation. A controller is configured to control the PET image reconstruction unit to change the parameter used in the successive approximation depending on information regarding the scanning region in the body of the subject.

摘要翻译： 在根据一个实施例的作为医学图像诊断装置的核医学成像装置中，PET检测器被配置为检测从引入到对象体内的核素发射的γ射线。 PET图像重建单元被配置为从基于由PET检测器检测的伽马射线创建的伽马射线投影数据逐次逼近来重建作为医学图像的核医学图像（PET图像）。 控制器被配置为根据与被摄体的身体中的扫描区域有关的信息来控制PET图像重建单元改变在逐次逼近中使用的参数。

公开(公告)号：US07420176B2

公开(公告)日：2008-09-02

申请号：US11244283

申请日：2005-10-06

申请人： Nobutoku Motomura ,  Hisato Maeda

发明人： Nobutoku Motomura ,  Hisato Maeda

IPC分类号： G21G4/00

CPC分类号： A61B6/12 ,  A61B5/4839 ,  A61B6/037 ,  G01T1/1647

摘要： A SPECT apparatus has a two-dimensional detector that detects radiations from RIs in a patient via a collimator. A correction processing unit corrects plural two-dimensional projection distributions with different projection angles, which are detected by the detector, on a three-dimensional frequency space according to plural correction functions corresponding to plural distances, respectively. Consequently, a fall in spatial resolution having dependency on distances between the respective RIs and the detector is reduced. A reconfiguring unit reconfigures a three-dimensional RI distribution from the plural two-dimensional projection distributions corrected.

摘要翻译： SPECT装置具有二维检测器，其通过准直器检测来自患者的RI的辐射。 校正处理单元分别根据对应于多个距离的多个校正功能，在三维频率空间上校正由检测器检测到的具有不同投影角度的多个二维投影分布。 因此，降低了依赖于相应的RI和检测器之间的距离的空间分辨率的下降。 重新配置单元从修正的多个二维投影分布重新配置三维RI分布。

公开(公告)号：US20060222145A1

公开(公告)日：2006-10-05

申请号：US11396450

申请日：2006-04-04

申请人： Nobutoku Motomura ,  Akiyosi Kinda

发明人： Nobutoku Motomura ,  Akiyosi Kinda

IPC分类号： H05G1/60 ,  A61B6/00 ,  G01N23/00 ,  G21K1/12

CPC分类号： A61B6/032 ,  A61B6/5235 ,  G06T11/005 ,  G06T2211/432 ,  Y10S378/901

摘要： A radiodiagnostic apparatus includes a data collection unit, a primary correction unit, a body contour detection unit, a secondary correction unit, and a reconstruction unit. The data collection unit collects a first projection data obtained at a projection angle within a projection angle range in which the whole portion of an object is within an effective acquisition field of a detector, and a second projection data obtained at a projection angle within a projection angle range in which a part of a truncated portion is out of the effective acquisition field of the detector, when the effective acquisition field of the detector is defined as a range limited by a collimator. The primary correction unit calculates a plurality of primary extrapolation expression candidates for correcting the second projection data so as to obtain third projection data candidates formed from the second projection data and the plurality of primary extrapolation expression candidates and for obtaining third projection data from the plurality of third projection data candidates. The body contour detection unit detects position information of a body contour in the second projection data. The secondary correction unit acquires a secondary extrapolation expression and for obtaining fourth projection data. The reconstruction unit reconstructs images on a slice-by-slice basis on the basis of the first projection data and the fourth projection data.

摘要翻译： 放射诊断装置包括数据采集单元，主要校正单元，身体轮廓检测单元，次要校正单元和重建单元。 数据收集单元收集以投影角度范围获得的投影角度的第一投影数据，其中物体的整个部分在检测器的有效采集场内，以及在投影中以投影角度获得的第二投影数据 当检测器的有效采集场被定义为由准直仪限制的范围时，截断部分的一部分超出检测器的有效采集场的角度范围。 主校正单元计算用于校正第二投影数据的多个主外插表达式候选，以便获得由第二投影数据和多个主外推表达式候选形成的第三投影数据候选，并且从多个 第三投影数据候选人。 身体轮廓检测单元检测第二投影数据中的身体轮廓的位置信息。 二次校正单元获取第二外推表达式并获得第四投影数据。 重建单元基于第一投影数据和第四投影数据逐个切片地重建图像。

公开(公告)号：US5173608A

公开(公告)日：1992-12-22

申请号：US659551

申请日：1991-02-22

申请人： Nobutoku Motomura ,  Takashi Ichihara

发明人： Nobutoku Motomura ,  Takashi Ichihara

IPC分类号： G01T1/164

CPC分类号： G01T1/1648 ,  G01T1/1642 ,  A61B6/037

摘要： In a gamma camera apparatus, positional shifts contained in an output coordinate matrix of a gamma-ray detector by a method comprising the steps of: positioning a reference RI (radio isotope) source at a first reference position the gamma-ray detector so as to obtain a first positional-information coordinate output from the gamma-ray detector; processing the first positional-information coordinate output indicative of a second reference position with respect to the matrix output derived from the detector so as to produce positional correction data; acquiring a third positional-information coordinate output from the detector while injecting a radio isotope into a biological body under medical examination; and, correcting the third positional-information coordinate output based upon the positional correction data.

摘要翻译： 在γ照相机装置中，通过包括以下步骤的方法，包含在γ射线检测器的输出坐标矩阵中的位置偏移：将参考RI（放射性同位素）源定位在第一参考位置处，将伽马射线检测器定位成 获得从伽马射线检测器输出的第一位置信息坐标; 处理相对于从检测器导出的矩阵输出指示第二参考位置的第一位置信息坐标输出，以产生位置校正数据; 获取从检测器输出的第三位置信息坐标，同时在体格检查下将放射性同位素注入生物体; 以及基于位置校正数据校正第三位置信息坐标输出。