公开(公告)号：US11492341B2

公开(公告)日：2022-11-08

申请号：US16684644

申请日：2019-11-15

Applicant: Nimbus Artemis, Inc.

Inventor： Silvana Marcel Leit de Moradei ,  Kevin Kreutter ,  H. James Harwood ,  Eric Therrien

IPC: C07D401/12 ,  C07D205/04 ,  C07D207/48 ,  C07D239/92 ,  C07D491/107 ,  C07D487/04 ,  C07D295/26 ,  C07D211/96 ,  C07D217/08 ,  C07D417/04 ,  C07D241/04 ,  C07D241/50 ,  C07D403/06 ,  C07D403/04 ,  C07D409/12 ,  C07D401/04 ,  C07D401/14 ,  C07D403/10 ,  C07D209/08

Abstract: The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.

公开(公告)号：US20200157076A1

公开(公告)日：2020-05-21

申请号：US16684644

申请日：2019-11-15

Applicant: Nimbus Artemis, Inc.

Inventor： Silvana Marcel Leit de Moradei ,  Kevin Kreutter ,  H. James Harwood ,  Eric Therrien

IPC: C07D401/12 ,  C07D209/08 ,  C07D491/107 ,  C07D487/04 ,  C07D295/26 ,  C07D205/04 ,  C07D211/96 ,  C07D207/48 ,  C07D217/08 ,  C07D417/04 ,  C07D241/04 ,  C07D241/50 ,  C07D403/06 ,  C07D403/04 ,  C07D409/12 ,  C07D401/04 ,  C07D401/14 ,  C07D403/10 ,  C07D239/92

Abstract: The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.

公开(公告)号：US11555012B2

公开(公告)日：2023-01-17

申请号：US16677768

申请日：2019-11-08

Applicant: Nimbus Artemis, Inc.

Inventor： Silvana Marcel Leit de Moradei ,  Eric Therrien

IPC: C07C311/29 ,  C07C311/21 ,  C07D491/113 ,  C07D295/135 ,  C07D333/20 ,  C07D257/04 ,  C07D295/10 ,  C07D205/04 ,  C07D277/34 ,  C07D209/80 ,  C07D231/38 ,  C07D263/32 ,  C07D401/12 ,  C07D413/06 ,  C07D401/04 ,  C07D409/12 ,  C07D213/04

Abstract: The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.

公开(公告)号：US20200148634A1

公开(公告)日：2020-05-14

申请号：US16677768

申请日：2019-11-08

Applicant: Nimbus Artemis, Inc.

Inventor： Silvana Marcel Leit de Moradei ,  Eric Therrien

IPC: C07C311/21 ,  C07D213/04 ,  C07D295/135 ,  C07D333/20 ,  C07D257/04 ,  C07D295/10 ,  C07D205/04 ,  C07D277/34 ,  C07D209/80 ,  C07D231/38 ,  C07D263/32 ,  C07D401/12 ,  C07D413/06 ,  C07D401/04 ,  C07D409/12 ,  C07D491/113

Abstract: The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.