Jasmonic acid and jasmonic acid ester stereoisomers and compositions
    1.
    发明授权
    Jasmonic acid and jasmonic acid ester stereoisomers and compositions 有权
    茉莉酸和茉莉酸酯立体异构体和组合物

    公开(公告)号:US07250160B2

    公开(公告)日:2007-07-31

    申请号:US10233924

    申请日:2002-09-03

    IPC分类号: A61K8/00 A01N37/00 A23L1/226

    摘要: Described is a bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate, as well as a novel jasmonic acid isomer produced thereby and organoleptic uses thereof. The process yields at least 5% of the “cis” isomer defined according the structure: (wherein R is hydrogen or methyl) or at least 5% of the “cis” isomer defined according to the structure: (wherein R is hydrogen or methyl). Compositions containing at least 98% of the isomer having the structure: with an optical rotation (αD20) of +58° are novel. Compositions containing at least 98% of the isomer having the structure: with an optical rotation (αD20) of +58° are also novel. The process of our invention comprises the cultivation under aerobic condition of one or more specific strain of Diplodia gossypina in a nutrient medium followed either by (1) isolation of the jasmonic acid product or (2) esterification of the jasmonic acid to form methyl jasmonate followed by the isolation of the methyl jasmonate and novel products produced by such process.

    摘要翻译: 描述了用于高产量生产食用香料可接受的茉莉酸和茉莉酮酸甲酯的生物过程,以及由此产生的新型茉莉酸异构体及其感官应用。 该方法得到根据以下结构定义的至少5%的“顺式”异构体:(其中R是氢或甲基)或根据以下结构定义的至少5%的“顺式”异构体:(其中R是氢或甲基 )。 含有至少98%具有以下结构的异构体的组合物:具有+ 58°的旋光度(α→20℃)是新颖的。 含有至少98%具有以下结构的异构体的组合物:具有+ 58°的旋光度(α→20°)也是新颖的。 本发明的方法包括在营养培养基中培养一种或多种特异性棉花Diplodia gossypina菌株的好氧条件,然后通过(1)分离茉莉酸产物或(2)茉莉酸酯化形成茉莉酸甲酯,随后 通过分离这种方法生产的茉莉酸甲酯和新产品。

    Bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate
    2.
    发明授权
    Bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate 有权
    用于高产量生产食用香料可接受的茉莉酸和茉莉酸甲酯的生物工艺

    公开(公告)号:US06333180B1

    公开(公告)日:2001-12-25

    申请号:US09468134

    申请日:1999-12-21

    IPC分类号: C12P1702

    摘要: Described is a bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate, as well as a novel jasmonic acid isomer produced thereby and organoleptic uses thereof. The process yields at least 5% of the “cis” isomer defined according the structure: (wherein R is hydrogen or methyl) or at least 5% of the “cis” isomer defined according to the structure: (wherein R is hydrogen or methyl). Compositions containing at least 98% of the isomer having the structure: with an optical rotation (&agr;D20) of +58° are novel. Compositions containing at least 98% of the isomer having the structure: with an optical rotation (&agr;D20) of +58° are also novel. The process of our invention comprises the cultivation under aerobic condition of one or more specific strain of Diplodia gossypina in a nutrient medium followed either by (1) isolation of the jasmonic acid product or (2) esterification of the jasmonic acid to form methyl jasmonate followed by the isolation of the methyl jasmonate and novel products produced by such process.

    摘要翻译: 描述了用于高产量生产食用香料可接受的茉莉酸和茉莉酮酸甲酯的生物过程,以及由此产生的新型茉莉酸异构体及其感官应用。 该方法得到根据以下结构定义的至少5%的“顺式”异构体:(其中R是氢或甲基)或根据以下结构定义的至少5%的“顺式”异构体:(其中R是氢或甲基 )。 含有至少98%具有以下结构的异构体的组合物:具有+ 58°的旋光度(αD20)是新颖的。 含有至少98%具有以下结构的异构体的组合物:具有+ 58°的旋光度(αD20)也是新颖的。 本发明的方法包括在营养培养基中培养一种或多种特异性棉花Diplodia gossypina菌株的好氧条件,然后通过(1)分离茉莉酸产物或(2)茉莉酸酯化形成茉莉酸甲酯,随后 通过分离这种方法生产的茉莉酸甲酯和新产品。

    Bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate, novel jasmonic acid isomer produced thereby and uses thereof
    3.
    发明授权
    Bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate, novel jasmonic acid isomer produced thereby and uses thereof 有权
    用于高产量生产食品香料可接受的茉莉酸和茉莉酸甲酯的生物工艺,由此产生的新颖茉莉酸异构体及其用途

    公开(公告)号:US06458569B1

    公开(公告)日:2002-10-01

    申请号:US09935320

    申请日:2001-08-22

    IPC分类号: C12P1702

    摘要: Described is a bioprocess for the high-yield production of food flavor-acceptable jasmonic acid and methyl jasmonate, as well as a novel jasmonic acid isomer produced thereby and organoleptic uses thereof. The process yields at least 5% of the “cis” isomer defined according the structure: (wherein R is hydrogen or methyl) or at least 5% of the “cis” isomer defined according to the structure: (wherein R is hydrogen or methyl). Compositions containing at least 98% of the isomer having the structure: with an optical rotation (&agr;D20) of +58° are novel. Compositions containing at least 98% of the isomer having the structure: with an optical rotation (&agr;D20) of +58° are also novel. The process of our invention comprises the cultivation under aerobic condition of one or more specific strain of Diplodia gossypina in a nutrient medium followed either by (1) isolation of the jasmonic acid product or (2) esterification of the jasmonic acid to form methyl jasmonate followed by the isolation of the methyl jasmonate and novel products produced by such process.

    摘要翻译: 描述了用于高产量生产食用香料可接受的茉莉酸和茉莉酮酸甲酯的生物过程,以及由此产生的新型茉莉酸异构体及其感官应用。 该方法得到根据以下结构定义的至少5%的“顺式”异构体:(其中R是氢或甲基)或根据以下结构定义的至少5%的“顺式”异构体:(其中R是氢或甲基 )。 含有至少98%具有以下结构的异构体的组合物:具有+ 58°的旋光度(αD20)是新颖的。 含有至少98%具有以下结构的异构体的组合物:具有+ 58°的旋光度(αD20)也是新颖的。 本发明的方法包括在营养培养基中培养一种或多种特异性棉花Diplodia gossypina菌株的好氧条件,然后通过(1)分离茉莉酸产物或(2)茉莉酸酯化形成茉莉酸甲酯,随后 通过分离这种方法生产的茉莉酸甲酯和新产品。