公开(公告)号：US20060289640A1

公开(公告)日：2006-12-28

申请号：US11436917

申请日：2006-05-18

申请人： Peter Mercure ,  Kristine Danowski ,  Larry Sun ,  Robert Haley ,  Douglas White ,  Michelle Pressler ,  Susan Babinec ,  Flor Castillo ,  Jahne Simon ,  Paul Cranley ,  Malcolm Warren ,  Diedre Strand ,  Bettina Rosner ,  Robert Fletcher ,  Christopher Jones ,  Thomas Kalantar ,  Mark Bernius ,  W. McDougall ,  Mark Felix

发明人： Peter Mercure ,  Kristine Danowski ,  Larry Sun ,  Robert Haley ,  Douglas White ,  Michelle Pressler ,  Susan Babinec ,  Flor Castillo ,  Jahne Simon ,  Paul Cranley ,  Malcolm Warren ,  Diedre Strand ,  Bettina Rosner ,  Robert Fletcher ,  Christopher Jones ,  Thomas Kalantar ,  Mark Bernius ,  W. McDougall ,  Mark Felix

IPC分类号： G06K7/00 ,  G08B13/14

CPC分类号： G06K19/04 ,  A01K11/007 ,  A61B5/4833 ,  A61J3/007 ,  A61J3/071 ,  A61J2200/30 ,  A61K9/0009 ,  A61K9/2072 ,  A61K9/4808 ,  G06K7/0008 ,  G06K7/10079 ,  G06K19/07327 ,  G06K19/07336 ,  G06K19/07345 ,  G06K19/07749 ,  H01Q1/2208 ,  H01Q1/273 ,  H01Q1/362 ,  H01Q7/00 ,  H01Q11/08

摘要： A device useful for oral drug delivery device consisting of: (a) a capsule, tablet or pill designed to disperse in the gastrointestinal system; (b) an RFID tag positioned in the capsule, tablet or pill, the RFID tag comprising an antenna; (c) an object selected from the group consisting of a magnet, a ferromagnetic object, a ferrite object and an electromagnetic shielding object positioned within, over or adjacent the antenna of the RFID tag to alter the antenna characteristics of the RFID tag so that if the RFID tag is interrogated before the capsule, tablet or pill disperses in the gastrointestinal system, the response of the RFID tag is sufficiently altered or attenuated to determine that the capsule, tablet or pill has not dispersed in the gastrointestinal system and so that if the RFID tag is interrogated after the capsule, tablet or pill has dispersed in the gastrointestinal system, the object separates from the RFID tag so that the response of the RFID tag is sufficiently detectable to determine that the capsule, tablet or pill has dispersed in the gastrointestinal system. Alternatively, a switch can be used to signal ingestion of the device, and change the response of the device. In another embodiment, the instant invention is a device useful for oral drug delivery, consisting of: (a) a capsule, tablet or pill designed to disperse in the gastrointestinal system; (b) a first non-anti-collision RFID tag positioned in the capsule; (c) a second non-anti-collision RFID tag positioned in the capsule, so that if the RFID tags are interrogated by an RFID reader before the capsule, tablet or pill disperses in the gastrointestinal system, the response of the RFID tags collide and so that after the dispersible material of the capsule has dispersed in the gastrointestinal system thereby allowing the first and second non-anti-collision tags to separate from each other, then the response of the RFID tags is sufficiently different from each other to determine that the capsule has dispersed in the gastrointestinal system