公开(公告)号：US10919952B2

公开(公告)日：2021-02-16

申请号：US16290859

申请日：2019-03-02

申请人： Xuechuan Wang ,  Mengdi Hou ,  Xinhua Liu ,  Chengyuan Liang ,  Ouyang Yue ,  Manhui Zheng ,  Xing Zhu ,  Qingxin Han ,  Ji Li ,  Huijie Zhang ,  Taotao Qiang

发明人： Xuechuan Wang ,  Mengdi Hou ,  Xinhua Liu ,  Chengyuan Liang ,  Ouyang Yue ,  Manhui Zheng ,  Xing Zhu ,  Qingxin Han ,  Ji Li ,  Huijie Zhang ,  Taotao Qiang

IPC分类号： C07K14/78

摘要： A method for preparing a collagen from a chromium-containing tanned leather waste is disclosed. The method includes acid dechromation, obtaining a collagen aggregate, and converting the collagen aggregate to the collagen. The method also includes a reaction in a supercritical carbon dioxide reactor.

公开(公告)号：US20220023507A1

公开(公告)日：2022-01-27

申请号：US17203689

申请日：2021-03-16

申请人： Xuechuan WANG ,  Manhui ZHENG ,  Xinhua LIU ,  Ouyang YUE ,  Mengdi HOU ,  Youyou WANG

发明人： Xuechuan WANG ,  Manhui ZHENG ,  Xinhua LIU ,  Ouyang YUE ,  Mengdi HOU ,  Youyou WANG

IPC分类号： A61L27/60 ,  A61L27/26 ,  A61L27/08 ,  B29B7/90 ,  B29C45/00

摘要： A method for preparing a conductive biomimetic skin scaffold material with self-repairing function includes the following steps: adding 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride to a homogeneous dispersion of acidified carbon nanotubes, poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS), and gelatin to cross-link to obtain a conductive composite colloid; and injecting the conductive composite colloid into a mold, aging at −4-4° C. for 12-24 hours, and then soaking in a phosphate-buffered saline (PBS) solution with a pH of 7.0-7.4 for 12-24 hours to obtain the conductive biomimetic skin scaffold material.

公开(公告)号：US11511018B2

公开(公告)日：2022-11-29

申请号：US17203689

申请日：2021-03-16

申请人： Xuechuan Wang ,  Manhui Zheng ,  Xinhua Liu ,  Ouyang Yue ,  Mengdi Hou ,  Youyou Wang

发明人： Xuechuan Wang ,  Manhui Zheng ,  Xinhua Liu ,  Ouyang Yue ,  Mengdi Hou ,  Youyou Wang

IPC分类号： A61L27/60 ,  A61L27/26 ,  A61L27/08 ,  B29B7/90 ,  B29C45/00 ,  B29K507/04 ,  B29L31/00 ,  B29K105/16

摘要： A method for preparing a conductive biomimetic skin scaffold material with self-repairing function includes the following steps: adding 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride to a homogeneous dispersion of acidified carbon nanotubes, poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS), and gelatin to cross-link to obtain a conductive composite colloid; and injecting the conductive composite colloid into a mold, aging at −4-4° C. for 12-24 hours, and then soaking in a phosphate-buffered saline (PBS) solution with a pH of 7.0-7.4 for 12-24 hours to obtain the conductive biomimetic skin scaffold material.

公开(公告)号：US20190309051A1

公开(公告)日：2019-10-10

申请号：US16290859

申请日：2019-03-02

申请人： Xuechuan WANG ,  Mengdi HOU ,  Xinhua LIU ,  Chengyuan LIANG ,  Ouyang YUE ,  Manhui ZHENG ,  Xing ZHU ,  Qingxin HAN ,  Ji LI ,  Huijie ZHANG ,  Taotao QIANG

发明人： Xuechuan WANG ,  Mengdi HOU ,  Xinhua LIU ,  Chengyuan LIANG ,  Ouyang YUE ,  Manhui ZHENG ,  Xing ZHU ,  Qingxin HAN ,  Ji LI ,  Huijie ZHANG ,  Taotao QIANG

IPC分类号： C07K14/78

摘要： A method for preparing a collagen from a chromium-containing tanned leather waste is disclosed. The method includes acid dechromation, obtaining a collagen aggregate, and converting the collagen aggregate to the collagen. The method also includes a reaction in a supercritical carbon dioxide reactor.