公开(公告)号：US20200311652A1

公开(公告)日：2020-10-01

申请号：US16812500

申请日：2020-03-09

申请人： MaineHealth

发明人： Heidi E. Morin

IPC分类号： G06Q10/06 ,  G16H40/20 ,  G06N20/00 ,  G06Q50/22

摘要： Embodiments of the innovation relate to a method for assigning staffing levels in a healthcare staffing device. The method includes displaying, by the healthcare staffing device, a set of patient acuity types associated with a department of a healthcare organization; receiving, by the healthcare staffing device, patient census information and patient acuity information for each patient acuity type of the set of patient acuity types associated with the department of the healthcare organization; applying, by the healthcare staffing device, staffing guidelines to the patient census information and patient acuity information for each patient acuity type; and outputting, by the healthcare staffing device, a staffing level indicator for the department of the healthcare organization based upon application of staffing guidelines to the patient census information and patient acuity information for each patient acuity type.

公开(公告)号：US20240327506A1

公开(公告)日：2024-10-03

申请号：US18620778

申请日：2024-03-28

申请人： MaineHealth

发明人： Xianghua Han ,  Jennifer M. Caron ,  Peter C. Brooks

IPC分类号： C07K16/18 ,  A61K35/17 ,  A61P35/00 ,  C07K16/28

CPC分类号： C07K16/18 ,  A61K35/17 ,  A61P35/00 ,  C07K16/2818 ,  C07K16/2827 ,  C07K16/2848

摘要： The present invention provides compositions and methods of use thereof in the treatment of cancer and abnormal immune suppression diseases by enhancing adoptive cell therapy. In some embodiments, the methods provided herein increase T-cell infiltration into a tumor.

公开(公告)号：US20240358850A1

公开(公告)日：2024-10-31

申请号：US18633864

申请日：2024-04-12

申请人： MaineHealth

发明人： Peter C. Brooks ,  Jennifer M. Caron

IPC分类号： A61K47/68 ,  A61K39/395 ,  A61P35/00

CPC分类号： A61K47/6843 ,  A61K39/3955 ,  A61K47/6803 ,  A61K47/68031 ,  A61K47/68033 ,  A61K47/68035 ,  A61K47/6809 ,  A61P35/00

摘要： The present invention provides compositions and methods of use thereof in the treatment of cancer and abnormal immune suppression diseases with antibodies an antigen binding fragments thereof which bind collagen and antibody drug conjugates (ADC). In some embodiments, in the methods provided herein the ADCs target non-cell surface targets associated with tumors.

公开(公告)号：US11998600B2

公开(公告)日：2024-06-04

申请号：US17110543

申请日：2020-12-03

申请人： MaineHealth

发明人： Peter C. Brooks ,  Jennifer M. Caron ,  Liangru Contois

IPC分类号： A61K39/395 ,  A61K38/39 ,  A61K39/00 ,  A61K45/06 ,  A61P35/00 ,  A61P37/04 ,  C07K14/78 ,  C07K16/18 ,  C07K16/28

CPC分类号： A61K39/3955 ,  A61K38/39 ,  A61K39/39558 ,  A61K45/06 ,  A61P35/00 ,  A61P37/04 ,  C07K14/78 ,  C07K16/18 ,  C07K16/2827 ,  A61K2039/505 ,  A61K2039/507 ,  C07K2317/34 ,  C07K2317/70 ,  C07K2317/73 ,  C07K2317/76

摘要： The present invention provides antagonists and methods of use thereof in the treatment of cancer and abnormal immune suppression diseases.

公开(公告)号：US11957366B2

公开(公告)日：2024-04-16

申请号：US17579190

申请日：2022-01-19

申请人： MaineHealth ,  Board of Trustees of the University of Maine System

发明人： Robert D. Ecker ,  Mohsen Shahinpoor

IPC分类号： A61B17/22 ,  A61B5/02 ,  A61B5/0215 ,  A61B5/026 ,  A61B17/50 ,  A61B34/30 ,  A61B17/00 ,  A61B17/12

CPC分类号： A61B17/22031 ,  A61B5/02007 ,  A61B5/0215 ,  A61B5/026 ,  A61B17/22012 ,  A61B17/22022 ,  A61B17/50 ,  A61B34/30 ,  A61B2017/00017 ,  A61B2017/00022 ,  A61B2017/00292 ,  A61B2017/12054 ,  A61B2034/301

摘要： The present disclosure relates to electrically controllable surgical tools. In general, surgical devices are provided having an electrically controllable, fingered operating end for use in angiography, endovascular and/or neurological surgery. The finger(s) at the operating end can be made from ionic polymer metal composite (IPMC) material to facilitate control of the finger(s).