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公开(公告)号：US20230408474A1
公开(公告)日：2023-12-21
申请号：US18250790
申请日：2021-10-21
发明人： Simon Woyke , Thomas Haller
CPC分类号： G01N33/0062 , G01N33/0031 , G01N33/0036 , G01J3/0202
摘要： The invention provides a device and a process for analysing the effect of a concentration of a gas on a sample, especially measurement of the gas concentration within a sample, and/or measurement of the effect of the absorption and/or desorption of a gas by the sample, using spectrophotometric detection of a gas-sensitive and optically detectable analyte of the sample while measuring the concentration of the gas in a gas composition that is continuously delivered to each sample well in order to contact the samples with a gas having a predetermined and/or measured concentration, respectively a pre-determined and/or measured partial pressure.
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公开(公告)号：US10369522B2
公开(公告)日：2019-08-06
申请号：US15107663
申请日：2014-12-23
发明人： Markus Kofler , Julia Dumpfarth , Michael Grimm , Georg Grimm , Gulnara Fauland , Thomas Bechtold
IPC分类号： B01D61/46 , B01D61/42 , G01N27/28 , G01N27/403
摘要： Electrochemical cell array for the treatment of a sample via electro-(end-)osmotic flow, comprising (i) an electrode chamber, comprising a cathodic compartment (CC) and an anodic compartment (AC), (ii) a cathode (C), being arranged in the cathodic compartment (CC), (iii) an anode (A), being arranged in the anodic compartment (AC), (iv) an intermediate cathodic compartment (C1) (v) an intermediate anodic compartment (A1) (iv) a first selective membrane (M1) being arranged between said cathodic compartment (CC) and said first intermediate cathodic compartment (C1) (v) a second selective membrane (M2) being arranged between said anodic compartment (AC) and said first intermediate anodic compartment (A1) (vi) a treatment compartment (T) for the sample being arranged between said intermediate cathodic compartment (C1) and said intermediate anodic compartment (A1), further comprising a first separator membrane (S1) between said treatment compartment (T) and said intermediate cathodic compartment (C1) and a second separator membrane (S2) arranged between said treatment compartment (T) and said intermediate anodic compartment (A1).
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公开(公告)号：US20160325230A1
公开(公告)日：2016-11-10
申请号：US15107663
申请日：2014-12-23
发明人： Markus Kofler , Julia Dumpfarth , Michael Grimm , Georg Grimm , Gulnara Fauland , Thomas Bechtold
CPC分类号： B01D61/427 , B01D61/422 , B01D61/46 , B01D2313/30 , B01D2313/345 , B01D2325/42 , G01N27/283 , G01N27/403
摘要： Electrochemical cell array for the treatment of a sample via electro-(end-)osmotic flow, comprising (i) an electrode chamber, comprising a cathodic compartment (CC) and an anodic compartment (AC), (ii) a cathode (C), being arranged in the cathodic compartment (CC), (iii) an anode (A), being arranged in the anodic compartment (AC), (iv) an intermediate cathodic compartment (C1) (v) an intermediate anodic compartment (A1) (iv) a first selective membrane (M1) being arranged between said cathodic compartment (CC) and said first intermediate cathodic compartment (C1) (v) a second selective membrane (M2) being arranged between said anodic compartment (AC) and said first intermediate anodic compartment (A1) (vi) a treatment compartment (T) for the sample being arranged between said intermediate cathodic compartment (C1) and said intermediate anodic compartment (A1), further comprising a first separator membrane (S1) between said treatment compartment (T) and said intermediate cathodic compartment (C1) and a second separator membrane (S2) arranged between said treatment compartment (T) and said intermediate anodic compartment (A1).
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公开(公告)号：US11839394B2
公开(公告)日：2023-12-12
申请号：US17358344
申请日：2021-06-25
IPC分类号： A61B17/225 , G10K11/28 , G10K15/04
CPC分类号： A61B17/225 , G10K11/28 , G10K15/043
摘要： The present invention relates to a reflector for an acoustic shock or pressure wave head, wherein the reflector comprises an acoustically reflective surface formed by a body of rotation, said body of rotation being formed by rotation of an elliptical segment about a rotation axis which extends through a focal point of the ellipse and encloses an angle α between 0.1° and 30° with the main axis of the ellipse.
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5.发明授权公开(公告)号：US11674923B2
公开(公告)日：2023-06-13
申请号：US16603441
申请日：2018-03-20
IPC分类号： G01N27/333 , A61B10/00 , G01N27/327 , G01N33/70
CPC分类号： G01N27/333 , A61B10/007 , G01N27/3275 , G01N33/70
摘要： The present invention relates to a single-use test-strip for the quantitative determination of sodium concentration and creatinine concentration and for the subsequent determination of their ratio, and to a non-invasive point-of-care (POC) device for detecting sodium depletion and/or sodium overload in a patient's body. Furthermore, the present invention relates to a method for simultaneously and quantitatively determining sodium concentration and creatinine concentration in a patient's urine sample and to a method of detecting sodium depletion and/or sodium overload in a patient's body.
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公开(公告)号：US11096706B2
公开(公告)日：2021-08-24
申请号：US15521141
申请日：2015-10-21
IPC分类号： A61B17/225 , G10K11/28 , G10K15/04
摘要： The present invention relates to a reflector for an acoustic shock or pressure wave head, wherein the reflector comprises an acoustically reflective surface formed by a body of rotation, said body of rotation being formed by rotation of an elliptical segment about a rotation axis which extends through a focal point of the ellipse and encloses an angle α between 0.1° and 30° with the main axis of the ellipse.
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7.发明申请公开(公告)号：US20200309726A1
公开(公告)日：2020-10-01
申请号：US16603441
申请日：2018-03-20
IPC分类号： G01N27/327 , A61B10/00
摘要： The present invention relates to a single-use test-strip for the quantitative determination of sodium concentration and creatinine concentration and for the subsequent determination of their ratio, and to a non-invasive point-of-care (POC) device for detecting sodium depletion and/or sodium overload in a patient's body. Furthermore, the present invention relates to a method for simultaneously and quantitatively determining sodium concentration and creatinine concentration in a patient's urine sample and to a method of detecting sodium depletion and/or sodium overload in a patient's body.
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公开(公告)号：US20210353320A1
公开(公告)日：2021-11-18
申请号：US17358344
申请日：2021-06-25
IPC分类号： A61B17/225
摘要： The present invention relates to a reflector for an acoustic shock or pressure wave head, wherein the reflector comprises an acoustically reflective surface formed by a body of rotation, said body of rotation being formed by rotation of an elliptical segment about a rotation axis which extends through a focal point of the ellipse and encloses an angle α between 0.1° and 30° with the main axis of the ellipse.
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公开(公告)号：US11033373B2
公开(公告)日：2021-06-15
申请号：US16463175
申请日：2017-11-21
摘要： The present disclosure relates to an intraoral suctioning device for intraoral negative pressure wound treatment and a method for manufacturing the same. In order to permanently maintain the negative pressure in a wound with a view to an improved wound treatment and regeneration process, the intraoral suctioning device for the intraoral negative pressure wound treatment as disclosed can include a dental splint, an elastic membrane sealing an aperture formed in the dental splint so as to define a sealed wound treatment area on the inside of the dental splint, and a suctioning channel system for evacuating the wound treatment area.
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公开(公告)号：US20190010547A1
公开(公告)日：2019-01-10
申请号：US15774001
申请日：2016-11-04
发明人： Peter Willeit , Manuel Mayr , Johann Willeit , Stefan Kiechl
IPC分类号： C12Q1/6883
摘要： The present invention relates to a predictive diagnostic method for identifying whether a patient will develop metabolic syndrome and/or type-2 diabetes in the future. In particular, the invention relates to a method for identifying a subject which has a risk for developing metabolic syndrome and/or type-2 diabetes, wherein the method comprises (a) analyzing (i.e. determining/measuring/quantifying) in a sample obtained from a test subject the amount of miR-122; and (b) identifying (i.e. detecting) a subject, which has a risk for developing metabolic syndrome and/or type-2 diabetes, wherein an increased amount of miR-122 as compared to the amount of miR-122 of a healthy reference population indicates a risk for developing metabolic syndrome and/or type-2 diabetes. Another aspect of the invention relates to a method for monitoring the therapeutic success during the treatment of metabolic syndrome and/or type-2 diabetes, wherein the method comprises (a) analyzing (i.e. determining/measuring/quantifying) in a first sample obtained from a test subject the amount of miR-122, wherein said first sample was obtained before or under treatment of the test subject with medication for metabolic syndrome and/or type-2 diabetes; (b) analyzing (i.e. determining/measuring/quantifying) in a second sample of said test subject the amount of miR-122, wherein said second sample was obtained under or after treatment of the test subject with medication for metabolic syndrome and/or type-2 diabetes; and (c) predicting the therapeutic success (i.e. detecting, whether therapeutic success exists), wherein a decreased amount of miR-122 in the second sample as compared to the first sample indicates therapeutic success.
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