专利检索 ap:"Lung Therapeutics, Inc." 第 1 页

1.

发明公开
MODIFIED CAVEOLIN-1 PEPTIDES FOR THE TREATMENT OF PATHOGEN-INDUCED LUNG INJURY 审中-公开

公开(公告)号：US20230226149A1

公开(公告)日：2023-07-20

申请号：US18002420

申请日：2021-06-17

申请人： Lung Therapeutics, Inc.

发明人： BreAnne MACKENZIE , Cory HOGABOAM , Brian WINDSOR

IPC分类号： A61K38/17 , A61K31/4706 , A61K31/675 , A61K31/4965 , A61K31/513 , A61K31/427

CPC分类号： A61K38/177 , A61K31/4706 , A61K31/675 , A61K31/4965 , A61K31/513 , A61K31/427

摘要： Provided herein are methods of using modified caveolin-1 (Cav-1) peptides to treat or prevent pathogen-induced lung injury and disrepair. In particular, provided are methods of using the modified Cav-1 peptides for the treatment of pathogen-induced lung injury and disrepair caused by a coronavirus, such as, for example, SARS-CoV-2.

2.

发明申请
COMPOSITIONS AND METHODS FOR PROTECTING TYPE 2 ALVEOLAR EPITHELIAL CELLS (AEC2) 有权

公开(公告)号：US20220160814A1

公开(公告)日：2022-05-26

申请号：US17437952

申请日：2020-03-11

申请人： Lung Therapeutics, Inc.

发明人： Roxana WASNICK , Andreas GUENTHER

IPC分类号： A61K38/08 , A61K45/06 , A61K38/10

摘要： Provided herein are compositions comprising caveolin-1 (Cav-1) peptides and methods of using said compositions to protect type 2 alveolar epithelial cells from injury- or disease-induced apoptosis as well as increase the expression of the ABCA3 and SpC proteins.

3.

发明公开
MODIFIED PEPTIDE FRAGMENTS OF CAV-1 PROTEIN AND THE USE THEREOF IN THE TREATMENT OF FIBROSIS 审中-公开

公开(公告)号：US20240018186A1

公开(公告)日：2024-01-18

申请号：US18460215

申请日：2023-09-01

申请人： Lung Therapeutics, Inc.

发明人： Dale CHRISTENSEN , John J. KOLENG

IPC分类号： C07K7/06 , A61K45/06 , C07K7/08 , C07K14/705

CPC分类号： C07K7/06 , A61K45/06 , C07K7/08 , C07K14/705 , A61K38/00

摘要： Provided herein are compositions comprising modified caveolin-1 (Cav-1) peptides. Further provided are methods of using the modified Cav-1 peptides for the treatment of lung infections or acute or chronic lung injury, particularly lung fibrosis.

4.

发明授权
Modified peptide fragments of CAV-1 protein and the use thereof in the treatment of fibrosis 有权

公开(公告)号：US11905336B2

公开(公告)日：2024-02-20

申请号：US17274721

申请日：2019-09-10

申请人： Lung Therapeutics, Inc.

发明人： Dale Christensen , John J. Koleng

IPC分类号： A61K45/06 , C07K7/08 , C07K14/705 , A61K38/00 , C07K7/06

CPC分类号： C07K7/06 , A61K45/06 , C07K7/08 , C07K14/705 , A61K38/00 , C07K2319/10

摘要： Provided herein are compositions comprising modified caveolin-1 (Cav-1) peptides. Further provided are methods of using the modified Cav-1 peptides for the treatment of lung infections or acute or chronic lung injury, particularly lung fibrosis.

5.

发明公开
MODIFIED PEPTIDE FRAGMENTS OF CAV-1 PROTEIN AND THE USE THEREOF IN THE TREATMENT OF FIBROSIS 审中-公开

公开(公告)号：US20230212223A1

公开(公告)日：2023-07-06

申请号：US18069541

申请日：2022-12-21

申请人： Lung Therapeutics, Inc.

发明人： Dale CHRISTENSEN , John J. KOLENG

IPC分类号： C07K7/06 , A61K45/06 , C07K7/08 , C07K14/705

CPC分类号： C07K7/06 , A61K45/06 , C07K7/08 , C07K14/705 , A61K38/00

摘要： Provided herein are compositions comprising modified caveolin-1 (Cav-1) peptides. Further provided are methods of using the modified Cav-1 peptides for the treatment of lung infections or acute or chronic lung injury, particularly lung fibrosis.

6.

发明公开
MODIFIED PEPTIDE FRAGMENTS OF CAV-1 PROTEIN AND USES THEREOF 审中-公开

公开(公告)号：US20230159608A1

公开(公告)日：2023-05-25

申请号：US17920517

申请日：2021-04-21

申请人： Lung Therapeutics, Inc.

发明人： Brian WINDSOR

IPC分类号： C07K14/705 , A61K45/06

CPC分类号： C07K14/705 , A61K45/06 , A61K38/00

摘要： Provided herein are compositions comprising modified caveolin-1 (Cav-1) peptides. Further provided are methods of using the modified Cav-1 peptides for the treatment of pulmonary hypertension, lung infections or acute or chronic lung injury, particularly lung fibrosis.

7.

发明申请
DRY POWDER FORMULATION OF CAVEOLIN-1 PEPTIDES AND METHODS OF USE THEREOF 有权

公开(公告)号：US20210260150A1

公开(公告)日：2021-08-26

申请号：US17274666

申请日：2019-09-10

申请人： BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM , LUNG THERAPEUTICS, INC.

发明人： Robert O. WILLIAMS, III , Alan B. WATTS , Yajie ZHANG , Sawittree SAHAKIJPIJARN , Dale CHRISTENSEN , John J. KOLENG

IPC分类号： A61K38/08 , A61P11/00 , A61K38/10 , A61K9/00 , A61K45/06 , A61K9/14

摘要： Provided herein are compositions comprising caveolin-1 (Cav-1) peptides. Further provided are methods of using the Cav-1 peptides for the treatment of lung infections or acute or chronic lung injury, particularly lung fibrosis.

8.

发明授权
Modified peptide fragments of CAV-1 protein and the use thereof in the treatment of fibrosis 有权

公开(公告)号：US11787838B2

公开(公告)日：2023-10-17

申请号：US18069541

申请日：2022-12-21

申请人： Lung Therapeutics, Inc.

发明人： Dale Christensen , John J. Koleng

IPC分类号： A61K45/06 , C07K7/08 , A61K38/00 , C07K7/06 , C07K14/705

CPC分类号： C07K7/06 , A61K45/06 , C07K7/08 , C07K14/705 , A61K38/00 , C07K2319/10

摘要： Provided herein are compositions comprising modified caveolin-1 (Cav-1) peptides. Further provided are methods of using the modified Cav-1 peptides for the treatment of lung infections or acute or chronic lung injury, particularly lung fibrosis.

9.

发明申请
MODIFIED PEPTIDE FRAGMENTS OF CAV-1 PROTEIN AND THE USE THEREOF IN THE TREATMENT OF FIBROSIS 有权

公开(公告)号：US20210347820A1

公开(公告)日：2021-11-11

申请号：US17274721

申请日：2019-09-10

申请人： Lung Therapeutics, Inc.

发明人： Dale CHRISTENSEN , John J. KOLENG

IPC分类号： C07K7/06 , C07K7/08 , C07K14/705 , A61K45/06

摘要： Provided herein are compositions comprising modified caveolin-1 (Cav-1) peptides. Further provided are methods of using the modified Cav-1 peptides for the treatment of lung infections or acute or chronic lung injury, particularly lung fibrosis.