公开(公告)号：US08634930B2

公开(公告)日：2014-01-21

申请号：US11428070

申请日：2006-06-30

Applicant: Yousufali Dalal ,  Andrew P. Kramer ,  Lizbeth M. Mino

Inventor： Yousufali Dalal ,  Andrew P. Kramer ,  Lizbeth M. Mino

IPC: A61N1/36

CPC classification number: A61N1/37288 ,  A61N1/36007 ,  A61N1/36014 ,  A61N1/36053 ,  A61N1/36114 ,  A61N1/36135 ,  A61N1/3621 ,  A61N1/36557 ,  A61N1/36585 ,  A61N1/37282

Abstract: Various system embodiments include a glucose control input, a low physical activity input, and a diabetic therapy delivery system adapted to respond to the glucose control input and the low physical activity input to deliver diabetic therapy. According to various embodiments, the diabetic therapy includes an anti-arrhythmia therapy, a hypertension therapy, a neural stimulation therapy adapted to reduce a risk of myocardial infarction, a neural stimulation therapy adapted to be applied after a myocardial infarction to reduce an infarct area, a neural stimulation therapy adapted to reduce a risk of sudden cardiac death, a therapy adapted to secrete insulin, or a therapy to reduce a workload of a diabetic heart. Other aspects and embodiments are provided herein.

Abstract translation: 各种系统实施方案包括葡萄糖控制输入，低体力活动输入和适于响应于葡萄糖控制输入和低体力活动输入以递送糖尿病治疗的糖尿病治疗递送系统。 根据各种实施方案，糖尿病治疗包括抗心律失常治疗，高血压治疗，适于降低心肌梗死风险的神经刺激疗法，适于在心肌梗死后应用以减少梗死面积的神经刺激疗法， 适于减少心源性猝死的风险的神经刺激疗法，适于分泌胰岛素的治疗剂或减少糖尿病心脏的工作量的治疗方法。 本文提供了其它方面和实施例。

公开(公告)号：US20090018404A1

公开(公告)日：2009-01-15

申请号：US11776744

申请日：2007-07-12

Applicant: Lahn M. Fendelander ,  Lizbeth M. Mino ,  Aaron R. McCabe

Inventor： Lahn M. Fendelander ,  Lizbeth M. Mino ,  Aaron R. McCabe

IPC: A61B5/00

CPC classification number: A61B5/02405 ,  A61B5/0031 ,  A61B5/0205 ,  A61B5/4035 ,  A61N1/36514 ,  A61N1/3702

Abstract: A test system and method for cardiovascular autonomic neuropathy that incorporates an implanted medical device. One aspect of the invention relates to a system for performing cardiovascular autonomic neuropathy (CAN) testing in a diabetic patient having an implantable medical device (IMD) that includes a plurality of implantable physiological sensors and that is configured to transmit a wireless signal corresponding to a sensed physiological activity and to receive wireless signals. The system further includes one or more non-implantable physiological sensors, where the non-implantable physiological sensors are each configured to transmit a signal corresponding to a sensed physiological parameter, and a monitor device having a patient interface. The monitor device is configured to interface with a patient, including directing the patient to answer health related questions and use one or more of the non-implantable physiological sensors. The monitor device is also configured to receive signals, including signals from the IMD and the non-implantable physiological sensors. The system is configured to provide an indication of the presence or progression of CAN.

Abstract translation: 一种纳入植入式医疗设备的心血管自主神经病变的测试系统和方法。 本发明的一个方面涉及一种用于在具有植入式医疗装置（IMD）的糖尿病患者中进行心血管自主神经病变（CAN）测试的系统，所述植入式医疗装置包括多个可植入的生理传感器，并且被配置为发送对应于 感知生理活动并接收无线信号。 该系统还包括一个或多个不可植入的生理传感器，其中非植入式生理传感器各自被配置为传送对应于所感测的生理参数的信号，以及具有患者接口的监测装置。 监视器装置被配置为与患者接口，包括引导患者回答健康相关问题并使用一个或多个非植入式生理传感器。 监视器装置还被配置为接收包括来自IMD和非植入式生理传感器的信号的信号。 该系统被配置为提供CAN的存在或进展的指示。

公开(公告)号：US20080004672A1

公开(公告)日：2008-01-03

申请号：US11428070

申请日：2006-06-30

Applicant: Yousufali Dalal ,  Andrew P. Kramer ,  Lizbeth M. Mino

Inventor： Yousufali Dalal ,  Andrew P. Kramer ,  Lizbeth M. Mino

IPC: A61N1/18

CPC classification number: A61N1/37288 ,  A61N1/36007 ,  A61N1/36014 ,  A61N1/36053 ,  A61N1/36114 ,  A61N1/36135 ,  A61N1/3621 ,  A61N1/36557 ,  A61N1/36585 ,  A61N1/37282

Abstract: Various system embodiments include a glucose control input, a low physical activity input, and a diabetic therapy delivery system adapted to respond to the glucose control input and the low physical activity input to deliver diabetic therapy. According to various embodiments, the diabetic therapy includes an anti-arrhythmia therapy, a hypertension therapy, a neural stimulation therapy adapted to reduce a risk of myocardial infarction, a neural stimulation therapy adapted to be applied after a myocardial infarction to reduce an infarct area, a neural stimulation therapy adapted to reduce a risk of sudden cardiac death, a therapy adapted to secrete insulin, or a therapy to reduce a workload of a diabetic heart. Other aspects and embodiments are provided herein.

Abstract translation: 各种系统实施方案包括葡萄糖控制输入，低体力活动输入和适于响应于葡萄糖控制输入和低体力活动输入以递送糖尿病治疗的糖尿病治疗递送系统。 根据各种实施方案，糖尿病治疗包括抗心律失常治疗，高血压治疗，适于降低心肌梗死风险的神经刺激疗法，适于在心肌梗死后应用以减少梗死面积的神经刺激疗法， 适于减少心源性猝死的风险的神经刺激疗法，适于分泌胰岛素的治疗剂或减少糖尿病心脏的工作量的治疗方法。 本文提供了其它方面和实施例。