公开(公告)号：US20140030193A1

公开(公告)日：2014-01-30

申请号：US14111158

申请日：2012-04-11

Applicant: Peter C. Searson ,  Justin Galloway ,  Kwan Hyi Lee ,  Jea Ho Park

Inventor： Peter C. Searson ,  Justin Galloway ,  Kwan Hyi Lee ,  Jea Ho Park

IPC: A61K49/00

CPC classification number: A61K49/0067 ,  A61K49/0017 ,  A61K49/0058 ,  B82Y15/00 ,  G01N33/588

Abstract: Applications in nanomedicine, such as diagnostics and targeted therapeutics, rely on the detection and targeting of membrane biomarkers. Disclosed herein are functionalized quantum dots exhibiting greater stability in water, methods of making the functionalized quantum dots and methods of in vivo imaging using the functionalized quantum dots.

Abstract translation: 纳米医学中的应用，如诊断和靶向治疗，依赖于膜生物标志物的检测和靶向。 本文公开了在水中显示出更大稳定性的官能化量子点，制备官能化量子点的方法和使用官能化量子点的体内成像方法。

公开(公告)号：US20120100560A1

公开(公告)日：2012-04-26

申请号：US13190290

申请日：2011-07-25

Applicant: Peter C. Searson ,  Kwan Hyi Lee ,  Konstantinos Konstantopoulos ,  ZiQiu Tong

Inventor： Peter C. Searson ,  Kwan Hyi Lee ,  Konstantinos Konstantopoulos ,  ZiQiu Tong

IPC: G01N33/574 ,  C12M1/34 ,  B82Y5/00 ,  B82Y15/00

CPC classification number: G01N33/57438 ,  B82Y15/00 ,  G01N33/57473 ,  G01N33/588 ,  G01N2333/4725

Abstract: Applications in nanomedicine, such as diagnostics and targeted therapeutics, rely on the detection and targeting of membrane biomarkers. The present invention, in one embodiment, utilizes quantitative profiling, spatial mapping, and multiplexing of cancer biomarkers using functionalized quantum dots. This approach provides highly selective targeting molecular markers for pancreatic cancer with extremely low levels of non-specific binding and provides quantitative spatial information of biomarker distribution on a single cell, which is important since tumors cell populations are inherently heterogeneous. The quantitative measurements (number of molecules per square micron) is validated using flow cytometry and demonstrated using multiplexed quantitative profiling using color-coded quantum dots.

Abstract translation: 纳米医学中的应用，如诊断和靶向治疗，依赖于膜生物标志物的检测和靶向。 在一个实施方案中，本发明利用功能化量子点的癌症生物标志物的定量分析，空间映射和复用。 这种方法为具有极低水平的非特异性结合的胰腺癌提供了高选择性靶向分子标记，并提供了单个细胞上生物标志物分布的定量空间信息，这是重要的，因为肿瘤细胞群体本质上是异质性的。 使用流式细胞术验证定量测量（每平方微米分子数），并使用彩色量子点进行多重定量分析。

公开(公告)号：US20070023105A1

公开(公告)日：2007-02-01

申请号：US11323582

申请日：2005-12-29

Applicant: Won-Young Jeung ,  Kwan-Hyi Lee ,  Ho-Dong Park

Inventor： Won-Young Jeung ,  Kwan-Hyi Lee ,  Ho-Dong Park

IPC: C25D3/56

CPC classification number: C25D3/562

Abstract: The present invention relates to a CoPtP thin film having very high perpendicular magnetic anisotropy and a method for manufacturing the same. The method for manufacturing a CoPtP alloy thin film according to the present invention includes the steps of preparing an electroplating solution including CoSO4·7 H2O at 0.05˜0.2 M, H2PtCl6 at 0.005˜0.02 M, and NaH2PO2 at 0.01˜0.4 M, and dipping a basic material into the electroplating solution and forming the CoPtP alloy thin film on the basic material by electroplating at a low temperature.

Abstract translation: 本发明涉及具有非常高的垂直磁各向异性的CoPtP薄膜及其制造方法。 根据本发明的CoPtP合金薄膜的制造方法包括以下步骤：在0.05〜0.2M下制备包括CoSO 4·7H 2 O的电镀液， 在0.005〜0.02M的H 2 PtCl 6 6和0.01〜0.4M的NaH 2 PO 3，以及 将基本材料浸入电镀溶液中，并通过在低温下电镀在基材上形成CoPtP合金薄膜。

公开(公告)号：US07095070B2

公开(公告)日：2006-08-22

申请号：US10798447

申请日：2004-03-12

Applicant: Woo Young Lee ,  Kyung Ho Shin ,  Suk Hee Han ,  Joon Yeon Chang ,  Hi Jung Kim ,  Dal Young Kim ,  Kwan Hyi Lee ,  Kyoung Il Lee ,  Min Hong Jeun

Inventor： Woo Young Lee ,  Kyung Ho Shin ,  Suk Hee Han ,  Joon Yeon Chang ,  Hi Jung Kim ,  Dal Young Kim ,  Kwan Hyi Lee ,  Kyoung Il Lee ,  Min Hong Jeun

IPC: H01L31/062 ,  H01L21/00

CPC classification number: H01F10/1936 ,  C25D3/54 ,  C25D5/50 ,  G11C11/14 ,  H01F1/401 ,  H01F41/18 ,  H01F41/26 ,  H01L43/12

Abstract: In a method for fabricating a Bi thin film having a great MR (magnetoresistance) at room temperature and a method for fabricating a spintronics device using the same, the Bi thin film is fabricated by an electrodepostiting method and a sputtering method and has very great MR characteristics at room temperature, and it can be applied to various spintronics devices.

Abstract translation: 在室温下具有大的MR（磁阻）的Bi薄膜的制造方法以及使用该Bi薄膜的自旋电子学装置的制造方法中，Bi薄膜通过电沉积法和溅射法制造，具有非常大的MR 在室温下的特性，并且可以应用于各种自旋电子器件。