公开(公告)号：US20070293927A1

公开(公告)日：2007-12-20

申请号：US10589711

申请日：2004-04-16

申请人： Ko Frank ,  Robert Levy ,  Ivan Alferiev ,  Ilia Fishbein

发明人： Ko Frank ,  Robert Levy ,  Ivan Alferiev ,  Ilia Fishbein

IPC分类号： A61F2/06

CPC分类号： A61F2/90 ,  A61F2250/0067 ,  A61L31/16 ,  A61L2300/80

摘要： A device having polymeric filaments, wherein at least one of the filaments includes at least one groove for slidably retaining at least one other filament, such that the device is adapted to revert to a tubular lattice structure when allowed to expand from a collapsed state. A device as described above and further including a biologically active function, wherein the polymeric filaments of the device include an agent having a reactive group or a fiber adapted to covalently react with a biomaterial. Thus, the device of the invention has an active structural function such as the ability to regain a shape and, optionally, a biologically active function such as the ability to deliver a biomaterial to an organism or a cell. A process of manufacturing the device is also described.

摘要翻译： 一种具有聚合物长丝的装置，其中至少一根长丝包括至少一个用于可滑动地保持至少一个其它细丝的凹槽，使得该装置适于在允许从折叠状态膨胀时回复到管状格子结构。 如上所述的装置并且还包括生物活性功能，其中所述装置的聚合长丝包括具有反应性基团的试剂或适于与生物材料共价反应的纤维。 因此，本发明的装置具有活性结构功能，例如恢复形状和任选的生物活性功能的能力，例如将生物材料递送到生物体或细胞的能力。 还描述了制造该装置的过程。