公开(公告)号：US09022975B2

公开(公告)日：2015-05-05

申请号：US13611511

申请日：2012-09-12

申请人： John Goodman ,  Sonia Martins ,  Joseph B. Bilotta

发明人： John Goodman ,  Sonia Martins ,  Joseph B. Bilotta

IPC分类号： A61B17/00 ,  B01F5/06 ,  B01F13/00 ,  B05B15/02 ,  B05B1/32

CPC分类号： A61B17/00491 ,  A61B2017/00495 ,  B01F5/0683 ,  B01F5/069 ,  B01F13/0023 ,  B01F2215/0039 ,  B05B1/323 ,  B05B15/528

摘要： The invention described herein is a device for dripping a tissue sealant and/or adhesive that comprises a) first and second barrels or syringes that contain first and second biocomponents that are disposed between proximal and distal ends; b) a plunger in each barrel and c) a drip tip comprising i) a support having distal and proximal ends and at least two fluid passageways from the distal to the proximal end that are in fluid communication with one of the barrels of the dispensing device on the proximal end; and ii) an endcap that fits over the support having at least two flexible hinges. The present invention is also directed to an assembly for mixing and drip dispensing two reactive biologic components as tissue sealant and/or hemostatic agent and to methods for delivering biologic components to achieve hemostasis and/or tissue sealant by drip dispensing from the device described above.

摘要翻译： 本文描述的本发明是用于滴落组织密封剂和/或粘合剂的装置，其包括：a）第一和第二桶或注射器，其包含设置在近端和远端之间的第一和第二生物组分; b）每个筒体中的柱塞，c）滴头，其包括i）具有远端和近端的支撑件和从远端至近端的至少两个流体通道，其与分配装置的一个管道流体连通 在近端; 以及ii）装配在具有至少两个柔性铰链的支撑件上的端盖。 本发明还涉及一种用于混合和滴注两种反应性生物组分作为组织密封剂和/或止血剂的组合物，以及用于通过从上述装置滴注分泌生物组分以实现止血和/或组织密封剂的方法。

公开(公告)号：US20140074154A1

公开(公告)日：2014-03-13

申请号：US13611511

申请日：2012-09-12

申请人： John Goodman ,  Sonia Martins ,  Joseph B. Bilotta

发明人： John Goodman ,  Sonia Martins ,  Joseph B. Bilotta

IPC分类号： A61B17/00

CPC分类号： A61B17/00491 ,  A61B2017/00495 ,  B01F5/0683 ,  B01F5/069 ,  B01F13/0023 ,  B01F2215/0039 ,  B05B1/323 ,  B05B15/528

摘要： The invention described herein is a device for dripping a tissue sealant and/or adhesive that comprises a) first and second barrels or syringes that contain first and second biocomponents that are disposed between proximal and distal ends; b) a plunger in each barrel and c) a drip tip comprising i) a support having distal and proximal ends and at least two fluid passageways from the distal to the proximal end that are in fluid communication with one of the barrels of the dispensing device on the proximal end; and ii) an endcap that fits over the support having at least two flexible hinges. The present invention is also directed to an assembly for mixing and drip dispensing two reactive biologic components as tissue sealant and/or hemostatic agent and to methods for delivering biologic components to achieve hemostasis and/or tissue sealant by drip dispensing from the device described above.

摘要翻译： 本文描述的本发明是用于滴落组织密封剂和/或粘合剂的装置，其包括：a）第一和第二桶或注射器，其包含设置在近端和远端之间的第一和第二生物组分; b）每个筒体中的柱塞，c）滴头，其包括i）具有远端和近端的支撑件和从远端至近端的至少两个流体通道，其与分配装置的一个管道流体连通 在近端; 以及ii）装配在具有至少两个柔性铰链的支撑件上的端盖。 本发明还涉及一种用于混合和滴注两种反应性生物组分作为组织密封剂和/或止血剂的组合物，以及用于通过从上述装置滴注分泌生物组分以实现止血和/或组织密封剂的方法。