公开(公告)号：US09522006B2

公开(公告)日：2016-12-20

申请号：US13033532

申请日：2011-02-23

申请人： John R. Liddicoat ,  William E. Cohn

发明人： John R. Liddicoat ,  William E. Cohn

IPC分类号： A61B17/12 ,  A61B17/00

CPC分类号： A61B17/12013 ,  A61B17/00234 ,  A61B2017/00243

摘要： A novel catheter-based system that ligates the left atrial appendage (LAA) on the outside of the heart, preferably using a combination of catheters and/or instruments, e.g., a guide catheter inserted into the interior of the left atrial appendage that may assist in locating the left atrial appendage and/or assist in the optimal placement of a ligature or constricting element on the outside of the appendage, and a ligating catheter and/or instrument outside the heart in the pericardial space to set the ligature or constricting element at the neck of the left atrial appendage.

公开(公告)号：US08702703B2

公开(公告)日：2014-04-22

申请号：US12769345

申请日：2010-04-28

申请人： Mark T. Stewart ,  Tom P. Daigle ,  David E. Francischelli ,  John R. Liddicoat ,  Paul T. Rothstein ,  Steven F. Bolling

发明人： Mark T. Stewart ,  Tom P. Daigle ,  David E. Francischelli ,  John R. Liddicoat ,  Paul T. Rothstein ,  Steven F. Bolling

IPC分类号： A61B18/18

CPC分类号： A61B18/1445 ,  A61B1/00087 ,  A61B1/05 ,  A61B1/06 ,  A61B34/20 ,  A61B2017/00057 ,  A61B2017/2945 ,  A61B2018/00107 ,  A61B2018/00142 ,  A61B2018/0022 ,  A61B2018/00375 ,  A61B2018/00982 ,  A61B2018/1432 ,  A61N1/362

摘要： Device and method for sub-xiphoid ablation of patient tissue. A sub-xiphoid access clamp has a handle, an elongate neck coupled to the handle and first and second opposing jaws. The first and second opposing jaws have first and second opposing relief segments being generally co-planar and concave with respect to one another to form a void therebetween, and first and second opposing elongate ablation elements positioned along the first and second opposing jaws and distal of the first and second opposing relief segments relative to the handle. The first and second opposing jaws are articulate between a closed position and an open position to admit, at least in part, a second portion of tissue of the patient within the void created by the first and second opposing relief segments while the first portion of tissue is positioned between the first and second ablation elements in the closed position.

摘要翻译： 患者组织亚硬膜切除术的装置及方法。 副剑杆通道夹具具有手柄，连接到手柄的细长颈部以及第一和第二相对的夹爪。 第一和第二相对的钳口具有第一和第二相对的浮雕段，它们大致共面并相对于彼此凹入以在它们之间形成空隙，并且第一和第二相对的细长消融元件沿着第一和第二相对的夹爪定位， 第一和第二相对的释放段相对于把手。 第一和第二相对的夹爪在关闭位置和打开位置之间铰接，以至少部分地允许患者在由第一和第二相对的浮雕段产生的空隙内的组织的第二部分，同时组织的第一部分 位于第一和第二消融元件之间处于关闭位置。

公开(公告)号：US20120010639A1

公开(公告)日：2012-01-12

申请号：US12932218

申请日：2011-02-18

申请人： John R. Liddicoat ,  William E. Cohn

发明人： John R. Liddicoat ,  William E. Cohn

IPC分类号： A61B17/08

CPC分类号： A61B17/072 ,  A61B17/00234 ,  A61B17/0218 ,  A61B17/07292 ,  A61B2017/00349 ,  A61B2017/00818 ,  A61B2017/00827 ,  A61B2017/00876 ,  A61B2017/07214 ,  A61B2017/2905 ,  A61B2017/306

摘要： Apparatus for reconfiguring tissue, the apparatus comprising a shaft having a distal end and a proximal end; at least one effector mechanism movably mounted to the distal end of the shaft, each effector mechanism comprising at least one gripping element for gripping tissue to that effector mechanism, the at least one effector mechanism being configured to capture the gripped tissue against said shaft, at least one actuating mechanism mounted to the proximal end of the shaft, and at least one connection mechanism connecting the at least one actuating mechanism to the at least one effector mechanism, whereby a user may utilize the at least one actuating mechanism to actuate the at least one effector mechanism so as to reconfigure tissue.

摘要翻译： 用于重构组织的装置，该装置包括具有远端和近端的轴; 至少一个效应器机构，其可移动地安装到所述轴的远端，每个效应器机构包括用于将组织夹持到所述效应器机构的至少一个夹持元件，所述至少一个效应器机构构造成将所述夹持的组织捕获在所述轴上， 安装到所述轴的近端的至少一个致动机构以及将所述至少一个致动机构连接到所述至少一个效应器机构的至少一个连接机构，由此使用者可以利用所述至少一个致动机构致动所述至少一个 一个效应器机制，以重新配置组织。

公开(公告)号：US20100249921A1

公开(公告)日：2010-09-30

申请号：US12797283

申请日：2010-06-09

申请人： William E. Cohn ,  Gregory H. Lambrecht ,  John R. Liddicoat ,  Robert Kevin Moore ,  Richard B. Streeter ,  Todd F. Davenport

发明人： William E. Cohn ,  Gregory H. Lambrecht ,  John R. Liddicoat ,  Robert Kevin Moore ,  Richard B. Streeter ,  Todd F. Davenport

IPC分类号： A61B17/22 ,  A61F2/24

CPC分类号： A61F2/2412 ,  A61F2/2427 ,  A61F2220/0016 ,  A61F2250/0059

摘要： Devices and methods for performing intravascular procedures without cardiac bypass include embodiments of temporary filter devices, temporary valves, and prosthetic valves. The temporary filter devices have a cannula which provides access for surgical tools for effecting repair of cardiac valves. The cannula may have filters which prevent embolitic material from entering the coronary arteries and aorta. The valve devices may also have a cannula for insertion of the valve into the aorta. The valve devices expand in the aorta to occupy the entire flow path of the vessel and operate to prevent blood flow and to permit flow through the valve. The prosthetic valves include valve fixation devices which secure the prosthetic valve to the wall of the vessel. The prosthetic valves are introduced into the vascular system in a compressed state, advanced to the site of implantation, and expanded and secured to the vessel wall.

摘要翻译： 不用心脏旁路进行血管内手术的装置和方法包括临时过滤装置，临时阀和人工瓣膜的实施例。 临时过滤装置具有套管，该套管为进行心脏瓣膜修复的外科手术工具提供通路。 套管可以具有防止栓塞材料进入冠状动脉和主动脉的过滤器。 瓣膜装置还可以具有用于将瓣膜插入主动脉的插管。 瓣膜装置在主动脉中膨胀以占据血管的整个流动路径，并且操作以防止血液流动并允许流过瓣膜。 假体瓣膜包括固定假体瓣膜至血管壁的瓣膜固定装置。 假体瓣膜以压缩状态引入血管系统中，前进到植入部位，并且扩张并固定到血管壁。

公开(公告)号：US07427291B2

公开(公告)日：2008-09-23

申请号：US11221393

申请日：2005-09-07

申请人： John R. Liddicoat ,  Brian Colyer Coppom ,  Richard B. Streeter

发明人： John R. Liddicoat ,  Brian Colyer Coppom ,  Richard B. Streeter

IPC分类号： A61F2/16

CPC分类号： A61F2/2448 ,  A61F2/2445 ,  A61F2/2466 ,  A61F2/2496 ,  A61F2250/001

摘要： This invention relates to a system used to fashion, size, and implant a tissue annuloplasty band. This system comprises (1) a device to cut tissue; (2) a device to fashion (i.e., roll, fold, bunch, etc.) the tissue into a band (i.e., the tissue annuloplasty band); and (3) a sizer that comprises an mounting ring which allows for determining and maintaining the proper size and shape of the tissue annuloplasty band while it is attached to the annulus of a heart valve. These components can be used alone, together as a system, or in any combination to fashion, size, and/or implant the tissue annuloplasty band.

摘要翻译： 本发明涉及一种用于对组织瓣环成形术带进行时间，尺寸和植入的系统。 该系统包括（1）切割组织的装置; （2）将组织（即，组织瓣环成形术带）方向（即，卷起，折叠，束等）的装置; 以及（3）包括安装环的定径机，所述安装环允许当其连接到心脏瓣膜的环形空间时，确定和保持组织瓣环成形术带的适当尺寸和形状。 这些组分可以单独使用，一起用作系统，或以任何组合方式使用，尺寸和/或植入组织瓣环成形术带。

公开(公告)号：US20080221593A1

公开(公告)日：2008-09-11

申请号：US12124023

申请日：2008-05-20

申请人： John R. Liddicoat ,  William E. Cohn ,  Roger Laham

发明人： John R. Liddicoat ,  William E. Cohn ,  Roger Laham

IPC分类号： A61B17/12 ,  A61B17/04

CPC分类号： A61B17/12013 ,  A61B17/00234 ,  A61B17/0467 ,  A61B17/12009 ,  A61B17/30 ,  A61B2017/00243 ,  A61B2017/00867 ,  A61B2017/00876 ,  A61B2017/12018 ,  A61B2017/308 ,  A61B2090/0811 ,  A61B2090/3966 ,  A61B2576/023 ,  A61F2/013 ,  A61F2230/0006 ,  A61F2230/005 ,  A61M25/0108 ,  A61M25/0127 ,  A61M25/10 ,  A61M29/02

摘要： A novel catheter-based system which ligates the left atrial appendage (LAA) on the outside of the heart, preferably using a combination of catheters and/or instruments, e.g., a guide catheter positioned inside the left atrial appendage which may assist in locating the left atrial appendage and/or assist in the optimal placement of a ligature on the outside of the appendage, and a ligating catheter and/or instrument outside the heart in the pericardial space to set a ligating element at the neck of the left atrial appendage.

摘要翻译： 一种新颖的基于导管的系统，其将心脏外侧的左心耳（LAA）结合，优选地使用导管和/或器械的组合，例如位于左心耳内的引导导管，其可以协助定位 左心耳和/或辅助将附件最佳放置在附肢的外侧，以及在心包空间内的心脏外的结扎导管和/或器械，以将结扎元件设置在左心耳的颈部。

公开(公告)号：US07097659B2

公开(公告)日：2006-08-29

申请号：US10414766

申请日：2003-04-16

申请人： Steven B. Woolfson ,  Richard B. Streeter ,  Daniel C. Taylor ,  John R. Liddicoat

发明人： Steven B. Woolfson ,  Richard B. Streeter ,  Daniel C. Taylor ,  John R. Liddicoat

IPC分类号： A61F2/24

CPC分类号： A61F2/2409 ,  A61F2/24 ,  A61F2/2403 ,  A61F2/2427 ,  A61F2/848 ,  A61F2220/0016 ,  A61F2230/0013

摘要： A fixation band for affixing a prosthetic heart valve to tissue, the fixation band comprising: a structure having a proximal end and a distal end in opposition to one another, and a lateral region between the proximal end and the distal end, wherein the prosthetic heart valve is attached to one of the proximal end and the distal end of the structure; a plurality of barbs selectively configurable between a first position and a second position, the barbs being contained within a peripheral boundary of the lateral region of the structure in the first position, and the barbs being extended from the peripheral boundary of the lateral region of the structure in the second position; and an actuator for selectively moving the plurality of barbs between the first position and the second position. A fixation band for affixing a prosthetic heart valve to tissue, the fixation band comprising: a proximal annular portion and a distal annular portion selectively positioned relatively to one another, the proximal annular portion and the distal annular portion each having a proximal side and a distal side, the proximal side of the distal annular portion and the distal side of the proximal annular portion being oriented toward one another, and the prosthetic heart valve being attached to one of the distal side of the distal annular portion and the proximal side of the proximal annular portion; a plurality of staples configured between the distal side of the proximal annular portion and the proximal side of the distal annular portion; and a compression device in attachment to the proximal annular portion and the distal annular portion, the compression device being configured to selectively position the proximal annular member and the distal annular member toward one another so as to compress the plurality of staples therebetween and deploy the plurality of staples into tissue so as to affix the prosthetic heart valve to the tissue.

公开(公告)号：US06890330B2

公开(公告)日：2005-05-10

申请号：US10014699

申请日：2001-10-26

申请人： Richard B. Streeter ,  John R. Liddicoat ,  Todd F. Davenport

发明人： Richard B. Streeter ,  John R. Liddicoat ,  Todd F. Davenport

IPC分类号： A61B17/00 ,  A61B17/02 ,  A61B17/34

CPC分类号： A61B17/3421 ,  A61B17/3498 ,  A61B2017/00243 ,  A61B2017/003 ,  A61B2017/0243 ,  A61B2017/3445 ,  A61B2017/3449 ,  A61B2017/3466 ,  A61B2017/3488

摘要： Apparatus is disclosed for providing access to a functioning vascular system of a patient, the apparatus comprising: a main body having sidewalls defining an interior region and an exterior region, a bottom end and a top end; a base being formed at the bottom end of the main body, securing means being configured on the base so as to allow attachment and formation of a seal between the base and the functioning vascular system of the patient, and the base being configurable to provide a passageway from the interior region of the main body to the functioning vascular system of the patient; and a cover being formed at the top end of the main body, wherein the cover provides a barrier between the interior region and the exterior region at the top end of the main body.

摘要翻译： 公开了用于提供对患者的功能性血管系统的访问的装置，该装置包括：主体，其具有限定内部区域和外部区域，底部端部和顶端的侧壁; 基部形成在主体的底端，固定装置构造在基部上，以便允许在基部和患者的功能性血管系统之间的密封的附接和形成，并且基座可配置成提供 从主体的内部区域到患者的功能性血管系统的通道; 以及盖，其形成在所述主体的顶端，其中所述盖在所述主体的顶端处在所述内部区域与所述外部区域之间提供阻挡层。

公开(公告)号：US06769434B2

公开(公告)日：2004-08-03

申请号：US09896259

申请日：2001-06-29

申请人： John R. Liddicoat ,  Gregory H. Lambrecht ,  Todd F. Davenport ,  William E. Cohn ,  Steven B. Woolfson ,  Daniel C. Taylor

发明人： John R. Liddicoat ,  Gregory H. Lambrecht ,  Todd F. Davenport ,  William E. Cohn ,  Steven B. Woolfson ,  Daniel C. Taylor

IPC分类号： A61B1900

CPC分类号： A61F2/2427 ,  Y10S623/902

摘要： A method for deploying an aortic valve prosthesis includes the steps of: making a first opening leading to the left atrium; passing the valve prosthesis through the opening and into a cardiac chamber of the left side of the heart using a first manipulation instrument; making a second opening in the arterial system and advancing one end of a second manipulation instrument through the arterial opening and into the cardiac chamber; securing the second manipulation instrument to the valve prosthesis; and using the second manipulation instrument to retract at least a portion of the valve prosthesis out of the cardiac chamber.

摘要翻译： 用于部署主动脉瓣假体的方法包括以下步骤：制造通向左心房的第一开口; 使用第一操纵器具将阀门假体穿过开口并进入心脏左侧的心室; 在动脉系统中形成第二个开口，并使第二个操纵器械的一端通过动脉开口进入心室; 将第二操纵仪器固定到瓣膜假体上; 以及使用所述第二操纵器械使所述瓣膜假体的至少一部分从所述心室收回。

公开(公告)号：US06702826B2

公开(公告)日：2004-03-09

申请号：US09888282

申请日：2001-06-22

申请人： John R. Liddicoat ,  Gregory H. Lambrecht ,  Richard B. Streeter ,  Steven B. Woolfson

发明人： John R. Liddicoat ,  Gregory H. Lambrecht ,  Richard B. Streeter ,  Steven B. Woolfson

IPC分类号： A61B17064

CPC分类号： A61B17/0684 ,  A61B17/00234 ,  A61B17/0466 ,  A61B17/064 ,  A61B17/0644 ,  A61B2017/00004 ,  A61B2017/00783 ,  A61B2017/0414 ,  A61B2017/0496 ,  A61B2017/0641 ,  A61F2/2445 ,  A61F2/2466

摘要： A novel system for performing a heart valve annuloplasty. The system involves the use of a plication band. In one embodiment, the annulus of the valve is reduced by constriction of the plication band itself. More particularly, each plication band enters the tissue at two or more points which are spaced from one other by a distance which is dictated by the geometry of the plication band. Subsequent constriction of the plication band causes these points to move toward each other, thereby constricting the tissue trapped between these points and thus reducing the overall circumference of the valve annulus. In a second embodiment, the annulus of the valve is reduced by linking multiple plication bands to one other, using a linkage construct, and then using a shortening of the length of the linkage construct between each plication band so as to gather the tissue between each plication band, whereby to reduce the overall circumference of the valve annulus.