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公开(公告)号：US08221315B2
公开(公告)日：2012-07-17
申请号：US11115064
申请日：2005-04-26
摘要： The present invention discloses devices and methods for performing intravascular procedures with out cardiac bypass. The devices include various embodiments of temporary filter devices, temporary valves, and prosthetic valves.The temporary filter devices have one or more cannulae which provide access for surgical tools for effecting repair of the cardiac valves. A cannula may have filters of various configurations encircling the distal region of the cannula, which prevent embolitic material from entering the coronary arteries and aorta.The temporary valve devices may also have one or more cannulae which guide the insertion of the valve into the aorta. The valve devices expand in the aorta to occupy the entire flow path of the vessel. In one embodiment, the temporary valve is a disc of flexible, porous, material that acts to filter blood passing therethrough. A set of valve leaflets extend peripherally from the disc. These leaflets can alternately collapse to prevent blood flow through the valve and extend to permit flow.The prosthetic valves include valve fixation devices which secure the prosthetic valve to the wall of the vessel. In one embodiment, the prosthetic valves have at least one substantially rigid strut, at least two expandable fixation rings located about the circumference of the base of the apex of the valve, and one or more commissures and leaflets. The prosthetic valves are introduced into the vascular system a compressed state, advanced to the site of implantation, expanded and secured to the vessel wall.
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公开(公告)号：US20060253129A1
公开(公告)日：2006-11-09
申请号：US11400714
申请日：2006-04-07
申请人： John Liddicoat , William Cohn
发明人： John Liddicoat , William Cohn
IPC分类号： A61B17/10
CPC分类号： A61B17/12013 , A61B17/00234 , A61B2017/00243
摘要： A novel catheter-based system that ligates the left atrial appendage (LAA) on the outside of the heart, preferably using a combination of catheters and/or instruments, e.g., a guide catheter inserted into the interior of the left atrial appendage that may assist in locating the left atrial appendage and/or assist in the optimal placement of a ligature or constricting element on the outside of the appendage, and a ligating catheter and/or instrument outside the heart in the pericardial space to set the ligature or constricting element at the neck of the left atrial appendage.
摘要翻译： 一种新颖的基于导管的系统，其将心脏外侧的左心耳（LAA）结合，优选地使用导管和/或器械的组合，例如插入左心耳内部的引导导管，其可以协助 在确定左心耳和/或协助在附件外侧的结扎或收缩元件的最佳放置以及在心包空间内的心脏外的结扎导管和/或器械以将结扎或收缩元件设置在 左心耳的颈部。
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3.发明申请Tissue annuloplasty band and apparatus and method for fashioning, sizing and implanting the same 有权组织瓣环成形术带及其形状，尺寸和植入方法公开(公告)号：US20060074486A1
公开(公告)日：2006-04-06
申请号：US11221393
申请日：2005-09-07
申请人： John Liddicoat , Brian Coppom , Richard Streeter
发明人： John Liddicoat , Brian Coppom , Richard Streeter
IPC分类号： A61F2/24 , A61B17/3205
CPC分类号： A61F2/2448 , A61F2/2445 , A61F2/2466 , A61F2/2496 , A61F2250/001
摘要： This invention relates to a system used to fashion, size, and implant a tissue annuloplasty band. This system comprises (1) a device to cut tissue; (2) a device to fashion (i.e., roll, fold, bunch, etc.) the tissue into a band (i.e., the tissue annuloplasty band); and (3) a sizer that comprises an mounting ring which allows for determining and maintaining the proper size and shape of the tissue annuloplasty band while it is attached to the annulus of a heart valve. These components can be used alone, together as a system, or in any combination to fashion, size, and/or implant the tissue annuloplasty band.
摘要翻译： 本发明涉及一种用于对组织瓣环成形术带进行时间，尺寸和植入的系统。 该系统包括（1）切割组织的装置; （2）将组织（即，组织瓣环成形术带）方向（即，卷起，折叠，束等）的装置; 以及（3）包括安装环的定径机，所述安装环允许当其连接到心脏瓣膜的环形空间时，确定和维持组织瓣环成形术带的适当尺寸和形状。 这些组分可以单独使用，一起用作系统，或以任何组合方式使用，尺寸和/或植入组织瓣环成形术带。
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公开(公告)号：US09101470B2
公开(公告)日：2015-08-11
申请号：US11115064
申请日：2005-04-26
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/0016 , A61F2250/0059
摘要： The present invention discloses devices and methods for performing intravascular procedures without cardiac bypass. The devices include various embodiments of temporary filter devices, temporary valves, and prosthetic valves.The temporary filter devices have one or more cannulae which provide access for surgical tools for effecting repair of the cardiac valves. A cannula may have filters of various configurations encircling the distal region of the cannula, which prevent embolitic material from entering the coronary arteries and aorta.The temporary valve devices may also have one or more cannulae which guide the insertion of the valve into the aorta. The valve devices expand in the aorta to occupy the entire flow path of the vessel. In one embodiment, the temporary valve is a disc of flexible, porous, material that acts to filter blood passing therethrough. A set of valve leaflets extend peripherally from the disc. These leaflets can alternately collapse to prevent blood flow through the valve and extend to permit flow.The prosthetic valves include valve fixation devices which secure the prosthetic valve to the wall of the vessel. In one embodiment, the prosthetic valves have at least one substantially rigid strut, at least two expandable fixation rings located about the circumference of the base of the apex of the valve, and one or more commissures and leaflets. The prosthetic valves are introduced into the vascular system a compressed state, advanced to the site of implantation, expanded and secured to the vessel wall.
摘要翻译： 本发明公开了一种在没有心脏旁路的情况下执行血管内手术的装置和方法。 这些装置包括临时过滤装置，临时阀和假肢阀的各种实施例。 临时过滤器装置具有一个或多个套管，其提供用于外科手术工具的进入以实现心脏瓣膜的修复。 套管可以具有围绕套管的远侧区域的各种构造的过滤器，其防止栓塞材料进入冠状动脉和主动脉。 临时阀装置还可以具有一个或多个引导阀插入主动脉的套管。 瓣膜装置在主动脉中扩张以占据血管的整个流动路径。 在一个实施例中，临时阀是柔性多孔材料的盘，其用于过滤血液中的血液。 一组瓣叶从圆盘外围延伸。 这些传单可以交替塌缩，以防止血液流过阀门并延伸以允许流动。 假体瓣膜包括固定假体瓣膜至血管壁的瓣膜固定装置。 在一个实施例中，人造瓣膜具有至少一个基本上刚性的支柱，围绕阀的顶点的基部的圆周定位的至少两个可扩张的固定环，以及一个或多个连合和传单。 人造瓣膜被引入血管系统中的压缩状态，前进到植入部位，扩张并固定到血管壁。
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公开(公告)号：US20060271175A1
公开(公告)日：2006-11-30
申请号：US11479357
申请日：2006-06-29
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/24 , A61F2/2403 , A61F2/2427 , A61F2/848 , A61F2220/0016 , A61F2230/0013
摘要： A fixation band for affixing a prosthetic heart valve to tissue having proximal and distal annular portions positionable relative to one another, the proximal and distal annular portions each having a proximal and distal sides, the proximal side of the distal annular portion and the distal side of the proximal annular portion being oriented toward one another, and a prosthetic heart valve being attachable to one of the distal side of the distal annular portion and the proximal side of the proximal annular portion; staples configured between the distal side of the proximal annular portion and the proximal side of the distal annular portion; and a compression device operative between the proximal and distal annular portions for selectively positioning the proximal and distal annular members toward one another for compressing the staples therebetween and deploying the staples into tissue so as to affix the prosthetic heart valve to tissue.
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公开(公告)号：US20050049679A1
公开(公告)日：2005-03-03
申请号：US10641975
申请日：2003-08-15
申请人： Daniel Taylor , John Liddicoat , Richard Streeter , Steven Woolfson , William Cohn , Todd Davenport , Thomas Kordis
发明人： Daniel Taylor , John Liddicoat , Richard Streeter , Steven Woolfson , William Cohn , Todd Davenport , Thomas Kordis
CPC分类号： A61F2/2451
摘要： A method and apparatus for reducing mitral regurgitation. The apparatus is inserted into the coronary sinus of a patient in the vicinity of the posterior leaflet of the mitral valve, the apparatus being adapted to straighten the natural curvature of at least a portion of the coronary sinus in the vicinity of the posterior leaflet of the mitral valve, whereby to move the posterior annulus anteriorly and thereby improve leaflet coaptation and reduce mitral regurgitation.
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公开(公告)号：US20050015112A1
公开(公告)日：2005-01-20
申请号：US10713386
申请日：2003-11-13
申请人： William Cohn , Gregory Lambrecht , John Liddicoat , Robert Moore , Richard Streeter , Todd Davenport
发明人： William Cohn , Gregory Lambrecht , John Liddicoat , Robert Moore , Richard Streeter , Todd Davenport
CPC分类号： A61F2/2412 , A61F2/2427 , A61F2220/0016 , A61F2250/0059
摘要： Devices and methods for performing intravascular procedures without cardiac bypass include embodiments of temporary filter devices, temporary valves, and prosthetic valves. The temporary filter devices have a cannula which provides access for surgical tools for effecting repair of cardiac valves. The cannula may have filters which prevent embolitic material from entering the coronary arteries and aorta. The valve devices may also have a cannula for insertion of the valve into the aorta. The valve devices expand in the aorta to occupy the entire flow path of the vessel and operate to prevent blood flow and to permit flow through the valve. The prosthetic valves include valve fixation devices which secure the prosthetic valve to the wall of the vessel. The prosthetic valves are introduced into the vascular system in a compressed state, advanced to the site of implantation, and expanded and secured to the vessel wall.
摘要翻译： 不用心脏旁路进行血管内手术的装置和方法包括临时过滤装置，临时阀和人工瓣膜的实施例。 临时过滤装置具有套管，该套管为进行心脏瓣膜修复的外科手术工具提供通路。 套管可以具有防止栓塞材料进入冠状动脉和主动脉的过滤器。 瓣膜装置还可以具有用于将瓣膜插入主动脉的插管。 瓣膜装置在主动脉中膨胀以占据血管的整个流动路径，并且操作以防止血液流动并允许流过瓣膜。 假体瓣膜包括固定假体瓣膜至血管壁的瓣膜固定装置。 假体瓣膜以压缩状态引入血管系统中，前进到植入部位，并且扩张并固定到血管壁。
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公开(公告)号：US20050010285A1
公开(公告)日：2005-01-13
申请号：US10787057
申请日：2004-02-25
申请人： Gregory Lambrecht , John Liddicoat , Robert Moore
发明人： Gregory Lambrecht , John Liddicoat , Robert Moore
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/0016 , A61F2250/0059
摘要： The present invention discloses devices and methods for performing intravascular procedures with out: cardiac bypass. The devices include various embodiments of temporary filter devices, temporary valves, and prosthetic valves. The temporary filter devices have one or more cannulae which provide access for surgical tools for effecting repair of the cardiac valves. A cannula may have filters of various configurations encircling the distal region of the cannula, which prevent embolitic material from entering the coronary arteries and aorta. The temporary valve devices may also have one or more cannulae which guide the insertion of the valve into the aorta. The valve devices expand in the aorta to occupy the entire flow path of the vessel. In one embodiment, the temporary valve is a disc of flexible, porous, material that acts to filter blood passing therethrough. A set of valve leaflets extend peripherally from the disc. These leaflets can alternately collapse to prevent blood flow through the valve and extend to permit flow. The prosthetic valves include valve fixation devices which secure the prosthetic valve to the wall of the vessel. In one embodiment, the prosthetic valves have at least one substantially rigid strut, at least two expandable fixation rings located about the circumference of the base of the apex of the valve, and one or more commissures and leaflets. The prosthetic valves are introduced into the vascular system a compressed state, advanced to the site of implantation, expanded and secured to the vessel wall.
摘要翻译： 本发明公开了用于进行血管内手术的装置和方法：心脏旁路。 这些装置包括临时过滤装置，临时阀和假肢阀的各种实施例。 临时过滤器装置具有一个或多个套管，其提供用于外科手术工具的进入以实现心脏瓣膜的修复。 套管可以具有围绕套管的远侧区域的各种构造的过滤器，其防止栓塞材料进入冠状动脉和主动脉。 临时阀装置还可以具有一个或多个引导阀插入主动脉的套管。 瓣膜装置在主动脉中扩张以占据血管的整个流动路径。 在一个实施例中，临时阀是柔性多孔材料的盘，其用于过滤血液中的血液。 一组瓣叶从圆盘外围延伸。
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公开(公告)号：US20050010246A1
公开(公告)日：2005-01-13
申请号：US10772782
申请日：2004-02-05
CPC分类号： A61F2/013 , A61F2/01 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/008
摘要： Apparatus for filtering and entrapping debris in the vascular system of a patient, the apparatus including a filter to allow blood to flow therethrough and to restrict passage of debris, wherein the filter captures debris carried in a first direction of blood flow. The apparatus further includes an entrapment mechanism which allows passage of debris and blood therethrough, in the first direction of blood flow and prevents debris passage in a second direction. The entrapment mechanism and filter allow blood and debris therethrough in the first direction of blood flow. The entrapment mechanism prevents debris flow in the second direction of blood flow. A method for filtering and entrapping debris in the vascular system includes inserting the apparatus into the vascular system, allowing blood and debris carried therein to flow through the entrapment mechanism, and removing the apparatus and accumulated debris from the vascular system.
摘要翻译： 用于过滤和捕获患者血管系统中的碎屑的装置，所述装置包括允许血液流过其中并且限制碎屑通过的过滤器，其中所述过滤器捕获沿第一血流方向携带的碎屑。 该装置还包括捕获机构，其允许碎屑和血液沿第一血流方向通过，并且防止碎片在第二方向上通过。 捕获机构和过滤器允许在第一血流方向上的血液和碎屑通过其中。 捕获机制防止泥石流在第二个血流方向。 用于过滤和捕获血管系统中的碎屑的方法包括将装置插入血管系统中，允许其中携带的血液和碎屑流过夹带机构，以及从血管系统移除装置并累积碎屑。
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公开(公告)号：US08591574B2
公开(公告)日：2013-11-26
申请号：US13220179
申请日：2011-08-29
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/0016 , A61F2250/0059
摘要： A method of performing an endovascular procedure within a patient can include inserting a filter into the patient's vascular system to restrict the passage of emboli through the filter while allowing blood to flow through the filter. The method can also include inserting a prosthetic valve into the patient's vascular system in a compressed state, and advancing the prosthetic valve to a site of implantation upstream of the filter. Additionally, the method includes implanting the prosthetic valve at the site of implantation by expanding at least a portion of the prosthetic value, and removing the filter from the patient's vascular system.
摘要翻译： 在患者体内执行血管内手术的方法可以包括将过滤器插入患者的血管系统中以限制栓塞通过过滤器，同时允许血液流过过滤器。 该方法还可以包括将假体瓣膜以压缩状态插入患者的血管系统中，并将人工瓣膜推进到过滤器上游的植入部位。 另外，该方法包括通过扩展假体值的至少一部分并从患者的血管系统移除过滤器来将植入瓣膜植入植入位置。
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