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公开(公告)号：US20080151777A1
公开(公告)日：2008-06-26
申请号：US11613251
申请日：2006-12-20
申请人： John David Allen , Rina R. Schneur
发明人： John David Allen , Rina R. Schneur
IPC分类号： H04L12/28
CPC分类号： H04L41/12 , H04L41/145 , H04L45/124
摘要： Systems and methods for core network topology router placement planning are provided. The systems and methods may use existing network data to create a data set and use the data set to optimize a network for the placement of routers.
摘要翻译： 提供了核心网络拓扑路由器布局规划的系统和方法。 系统和方法可以使用现有的网络数据来创建数据集并使用数据集来优化用于路由器的放置的网络。
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2.发明授权公开(公告)号：US06404733B1
公开(公告)日：2002-06-11
申请号：US09148943
申请日：1998-09-08
IPC分类号： H04L100
CPC分类号： H04L1/24
摘要： In a telecommunications network provisioned with a distributed restoration scheme, to determine the reactions and responses of the network while the network is “live” or operational, an exercise information message is provided to the network for presenting a simulated failure or failures thereto. This exercise information message is broadcast to all of the nodes of the network so that every node is aware of the simulated failure scenario. Modified DRA messages that indicate that they are exercise only messages are used by the nodes for executing the exercise restoration process. Such exercise restoration process will proceed as if an actual failure has occurred with the notable exception that no actual cross-connections will be made. Certain functionalities are provisioned to the nodes to allow the exercise restoration process to be aborted if a real failure is detected or upon the expiration of a timer. The exercise restoration process can also be terminated by a command from the network management.
摘要翻译： 在提供分布式恢复方案的电信网络中，为了在网络“直播”或运行时确定网络的反应和响应，向网络提供锻炼信息消息以呈现模拟的故障或故障。 该运动信息消息被广播到网络的所有节点，使得每个节点都知道模拟的故障情形。 指示它们是仅锻炼消息的修改的DRA消息被节点用于执行锻炼恢复过程。 这样的运动恢复过程将继续进行，好像发生了实际的故障，唯一的例外是没有实际的交叉连接。 某些功能被提供给节点，以允许在检测到真实故障或定时器到期时中止锻炼恢复过程。 锻炼恢复过程也可以通过来自网络管理的命令终止。
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3.发明授权公开(公告)号：US06294991B1
公开(公告)日：2001-09-25
申请号：US09149177
申请日：1998-09-08
申请人： John David Allen , Lee Bengston , Jasvantrai Shah
发明人： John David Allen , Lee Bengston , Jasvantrai Shah
IPC分类号： G08B2900
CPC分类号： H04Q3/0079 , H04L41/0654 , H04L41/0681 , H04Q2213/13056 , H04Q2213/13107 , H04Q2213/13162 , H04Q2213/13166 , H04Q2213/13167 , H04Q2213/13213 , H04Q2213/13349
摘要： To ensure that the distributed restoration process of a DRA provisioned network proceeds only in response to true failures, the present invention DRA network provisions to each of the ports of the nodes a timer mechanism for ascertaining whether an alarm is a genuine alarm. This is done by presetting the timer with an expiration period so that an alarm is validated as a failure only upon the expiration of the timer. When validated, the value of a counter is incremented. The value of the counter is reflective of the sum of validated alarms, and is compared against a preset threshold value. And it is only when the value of the summed validated alarms exceeds the preset threshold value would the DRA process be initiated. When a validated alarm ceases, the reverse process takes place. That is, the ending of the alarm has to be validated by another timer, which could be the same timer as used for validating an alarm. The counter is decremented for each validated non-alarm, so that when the value of the defect counter falls below the threshold value, the DRA process is reset.
摘要翻译： 为了确保DRA提供的网络的分布式恢复过程仅仅是为了响应真实故障而进行，本发明DRA网络向节点的每个端口提供定时器机制，用于确定报警是否是真实的报警。 这是通过将定时器预设为有效期来完成的，以便只有在定时器到期时才将故障验证为故障。 验证时，计数器的值增加。 计数器的值反映有效报警的总和，并与预设的阈值进行比较。 只有当总和的有效警报的值超过预设阈值时才能启动DRA进程。 当有效警报停止时，会发生相反的过程。 也就是说，报警的结束必须由另一个定时器进行验证，该定时器可能与用于验证报警的定时器相同。 对于每个经过验证的非报警，计数器递减，因此当缺陷计数器的值低于阈值时，DRA处理被复位。
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公开(公告)号：US5933590A
公开(公告)日：1999-08-03
申请号：US634319
申请日：1996-04-18
申请人： John David Allen
发明人： John David Allen
摘要： A system and method for restoring communications in a network having multiple span failures. After a failure is detected, a sender node in each of the plurality of sender-chooser pairs sends a failed status message to the other nodes in the network. The failed status message identifies a restoration priority of the particular sender-chooser pair. Upon receipt, other nodes in the network suspend processing of lower priority restoration efforts and queue lower priority messages if they are preempted by higher priority messages. Lower priority restoration efforts resume upon receipt of a finished status message from the sender node of the higher priority sender-chooser pair.
摘要翻译： 一种用于在具有多个跨度故障的网络中恢复通信的系统和方法。 在检测到故障之后，多个发送者选择对中的每一个中的发送者节点向网络中的其他节点发送故障状态消息。 失败的状态消息标识特定发送者选择对的恢复优先级。 一旦收到，网络中的其他节点将暂停处理较低优先级的恢复工作，并且如果优先级较高的消息被抢占，则排队低优先级消息。 在从较高优先级的发送者选择器对的发送方节点接收到完成的状态消息后，较低优先级恢复工作恢复。
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5.发明授权Communications system and method providing optimal restoration of failed-paths 失效通信系统和方法提供故障路径的最佳恢复
公开(公告)号：US5768256A
公开(公告)日：1998-06-16
申请号：US580718
申请日：1995-12-29
申请人： John David Allen , Lee D. Bengston
发明人： John David Allen , Lee D. Bengston
CPC分类号： H04Q3/0079 , H04L45/28 , H04L45/32
摘要： A system and method for restoring communications between a pair of nodes, between which communications have been broken, in a network. The method comprises the steps of designating one of the nodes a SENDER node and the other a CHOOSER node, where the SENDER and CHOOSER nodes each have a working port connected to a link bearing the interrupted communications; creating a forward restoration signature having a unique priority; selectively transmitting the forward restoration signal from the SENDER node based on its priority; upon receipt of a forward restoration signature at a TANDEM node, modifying and selectively transmitting the forward restoration signature based on its priority; upon receipt of a forward restoration signature at a spare port on the CHOOSER node, choosing the restoration path indicated by the received forward restoration signature, connecting the working port to the spare port, and transmitting a reverse restoration signature having the same priority as the forward restoration signature; upon receipt of a reverse restoration signature at a TANDEM node, based on the priority of the reverse restoration signature, modifying and selectively transmitting the reverse restoration signature, and connecting the port on which the reverse restoration signal was received to the port on which the corresponding forward restoration signature was originally received; and on receipt of a reverse restoration signature at a spare port on the SENDER node, connecting the spare port to the working port, thereby restoring communications between the pair of nodes.
摘要翻译： 一种在网络中恢复通信已经被破坏的一对节点之间的通信的系统和方法。 该方法包括以下步骤：将SENDER节点和另一个节点中的一个节点指定为CHOOSER节点，其中SENDER和CHOOSER节点各自具有连接到承载中断的通信的链路的工作端口; 创建具有唯一优先级的前向恢复签名; 基于其优先级选择性地发送来自SENDER节点的前向恢复信号; 在TANDEM节点接收到转发恢复签名时，根据其优先级修改和选择性地发送前向恢复签名; 在CHOOSER节点上的备用端口接收到正向恢复签名时，选择接收到的正向恢复签名指示的恢复路径，将工作端口连接到备用端口，并发送与前向相同优先级的反向恢复签名 恢复签名; 在TANDEM节点接收到反向恢复签名时，基于反向恢复签名的优先级，修改并选择性地发送反向恢复签名，并将其上接收到反向恢复信号的端口连接到其上对应的端口 最初收到正向恢复签名; 并且在SENDER节点的备用端口上接收到反向恢复签名，将备用端口连接到工作端口，从而恢复该对节点之间的通信。
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6.发明授权公开(公告)号：US08761183B2
公开(公告)日：2014-06-24
申请号：US11613251
申请日：2006-12-20
申请人： John David Allen , Rina R. Schneur
发明人： John David Allen , Rina R. Schneur
CPC分类号： H04L41/12 , H04L41/145 , H04L45/124
摘要： Systems and methods for core network topology router placement planning are provided. The systems and methods may use existing network data to create a data set and use the data set to optimize a network for the placement of routers.
摘要翻译： 提供了核心网络拓扑路由器布局规划的系统和方法。 系统和方法可以使用现有的网络数据来创建数据集并使用数据集来优化用于路由器的放置的网络。
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7.发明授权
公开(公告)号：US5748611A
公开(公告)日：1998-05-05
申请号：US673219
申请日：1996-06-27
CPC分类号： H04Q3/0079 , H04L41/0654 , H04L41/0896 , H04L43/0811 , H04L45/00 , H04L45/20 , H04L45/26 , H04L45/28 , H04L69/40 , H04Q3/0062
摘要： A system and method for restoration of a disrupted telecommunications path between a source node and a destination node via at least one tandem node. The operation of the present invention proceeds in five phases: notification, broadcast, path trace-out, confirmation and cleanup. In the notification phase, the path's source and destination nodes are notified of the disruption. In the broadcast phase, the network is flooded with PACK messages to locate restoration paths; selective rebroadcasting of the PACK messages limits the volume of restoration message traffic. In the path trace-out phase, bandwidth is conservatively reserved along the restoration paths indicated by the PACK messages. In the confirmation phase, restoration paths are built up step-wise along the traced-out paths, thereby restoring the disrupted path between the source and destination nodes. In the clean-up phase, all of the network resources that were allocated to restoration of the disrupted path, and that are no longer needed, are released.
摘要翻译： 一种用于经由至少一个串联节点恢复源节点和目的地节点之间的电信路径中断的系统和方法。 本发明的操作分为五个阶段：通知，广播，路径追踪，确认和清理。 在通知阶段，路径的源节点和目标节点被通知中断。 在广播阶段，网络充斥着PACK消息来定位恢复路径; PACK消息的选择性转播限制了恢复消息业务量。 在路径追溯阶段，沿PACK消息指示的恢复路径保留带宽。 在确认阶段，沿追踪路径逐步建立恢复路径，从而恢复源节点与目的节点之间的中断路径。 在清理阶段，所有分配给恢复中断路径的网络资源都已经被释放了。
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公开(公告)号：US20110178409A1
公开(公告)日：2011-07-21
申请号：US10585565
申请日：2005-02-28
申请人： Martin Russell Harris , Gavan Edmund Rosman , Roderick William Charles Vance , John David Allen
发明人： Martin Russell Harris , Gavan Edmund Rosman , Roderick William Charles Vance , John David Allen
CPC分类号： A61B5/6852 , A61B5/0066 , A61B5/0068 , G02B21/0028 , G02B23/2423 , G02B23/26
摘要： A microscope, endoscope or optical coherence tomograph, comprising a light source, a flexible light transmitter (18) for receiving and transmitting light from the light source, an optical element (20) with a forward end (30) for receiving the light from the light transmitter (18) and a rear wall (26) having an internal surface for reflecting the light laterally, and an external sleeve (14) enclosing the optical element (20) and transparent to the light in at least a region of the sleeve where the light is directed by the internal surface (26). The internal surface (26) has an optical figure suitable for focussing the light to an observational field (28) external to the sleeve (14). A confocal configuration may be used.
摘要翻译： 一种显微镜，内窥镜或光学相干断层摄影机，包括光源，用于从光源接收和透射光的柔性光发射器（18），具有用于接收来自所述光源的光的前端（30）的光学元件（20） 光发射器（18）和具有用于侧向反射光的内表面的后壁（26）和封装光学元件（20）的外部套筒（14），并且在至少一个套筒的区域中对光线透明 光被内表面（26）引导。 内表面（26）具有适于将光聚焦到套筒（14）外部的观察场（28）的光学图形。 可以使用共焦配置。
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9.发明授权
公开(公告)号：US5835482A
公开(公告)日：1998-11-10
申请号：US715323
申请日：1996-09-18
申请人： John David Allen
发明人： John David Allen
CPC分类号： H04L45/00 , H04L45/28 , H04Q3/0079
摘要： To restore partial outages within a communication network having numerous switching nodes and links interconnecting the nodes, a three-stage distributed restoration protocol is activated to use spare links to bypass failed links and restore normal network connectivity. The three-stage protocol detects and resolves contention for spare resources among separate restoration processes and is therefore particularly advantageous in the event of multiple simultaneous network failures. A conservative flooding approach is used during the first forward signalling stage. Data elements added to the forward signals convey the likelihood that the path will be needed for restoration. The second reverse signalling stage uses reverse signals with attached contention data to detect contention among separate processes for spare resources and to alert the respective processes. The final path implementation stage involves reviewing the reverse signals and using the attached contention data to make informed choices of restoration paths that result in the highest degree of overall network restoration. The present invention, including node logic and specific signal structures and multiple-pass signalling, allows for shared awareness among diverse restoration processes so that they may work collectively to best utilize available spare resources.
摘要翻译： 为了恢复具有多个交换节点和互连节点的链路的通信网络中的部分中断，三级分布式恢复协议被激活以使用备用链路绕过故障链路并恢复正常的网络连接。 三级协议检测并解决了在单独的恢复过程中的备用资源的争用，因此在多个同时的网络故障的情况下特别有利。 在第一个前向信令阶段使用了保守的泛洪方法。 添加到正向信号中的数据元素传达了恢复路径需要的可能性。 第二反向信令阶段使用具有附加争用数据的反向信号来检测用于备用资源的不同进程之间的争用并警告相应的进程。 最终的路径实现阶段涉及检查反向信号并使用附加的争用数据来做出导致最高程度的整体网络恢复的恢复路径的通知选择。 包括节点逻辑和特定信号结构以及多遍信令的本发明允许各种恢复过程之间的共享意识，使得它们可以共同工作以最佳地利用可用的备用资源。
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公开(公告)号：US20080227096A1
公开(公告)日：2008-09-18
申请号：US12000091
申请日：2007-12-07
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/106 , C12Q2600/158 , G01N33/57426 , G01N2800/52
摘要： The invention relates to a method for predicting a response to a proteasome inhibitor in the prophylaxis or treatment of a cancer in an individual. The method comprises providing a sample of cancer cells of the cancer from the individual, and evaluating the level of at least one molecule in the cancer cells associated with the unfolded protein response of the cancer cells, to provide test data indicative of the level of activity of the unfolded protein response. The test data is used to predict the response of the cancer cells to the proteasome inhibitor. The evaluation of the level of the molecule can be utilized for determination of treatment for the cancer.
摘要翻译： 本发明涉及预测个体中癌症预防或治疗中对蛋白酶体抑制剂的应答的方法。 该方法包括从个体提供癌症癌细胞的样品，并评估与癌细胞的未折叠蛋白反应相关的癌细胞中的至少一个分子的水平，以提供指示活性水平的测试数据 的展开蛋白质反应。 测试数据用于预测癌细胞对蛋白酶体抑制剂的反应。 分析水平的评估可用于确定癌症的治疗。
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