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公开(公告)号：US20110052626A1
公开(公告)日：2011-03-03
申请号：US12808971
申请日：2008-12-03
Applicant: Stéphane Bertagnoli , Béatrice Pignolet , Jacqueline Gelfi , Christelle Camus-Bouclainville
Inventor： Stéphane Bertagnoli , Béatrice Pignolet , Jacqueline Gelfi , Christelle Camus-Bouclainville
IPC: A61K39/275 , C12N7/01 , C07H21/04 , C12N15/63 , A61P31/20
CPC classification number: C07K16/081 , A61K2039/5254 , A61K2039/5256 , C07K14/005 , C07K2319/00 , C07K2319/40 , C07K2319/60 , C12N7/00 , C12N15/86 , C12N2710/24022 , C12N2710/24043 , C12N2710/24062
Abstract: The invention relates to modified leporipoxyinises expressing a chimeric envelope protein resulting from the fusion of an envelope protein of mature intracellular virions or of an envelope protein of enveloped extracellular virions, with an exogenous protein. These modified leporipoxviruses can be used in particular for obtaining vaccines.
Abstract translation: 本发明涉及由成熟细胞内病毒粒子的包膜蛋白或包膜的细胞外病毒颗粒的包膜蛋白与外源蛋白质融合而产生的表达嵌合包膜蛋白的修饰的脱氧核糖核酸酶。 这些改良的leporipoxvirus可特别用于获得疫苗。
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公开(公告)号：US08613915B2
公开(公告)日：2013-12-24
申请号：US13377386
申请日：2010-06-11
Applicant: Stéphane Bertagnoli , Magalie Gretillat , Jacqueline Gelfi , Christelle Camus-Bouclainville
Inventor： Stéphane Bertagnoli , Magalie Gretillat , Jacqueline Gelfi , Christelle Camus-Bouclainville
CPC classification number: A61K35/761 , C12N2710/24032
Abstract: The invention relates to the use of an attenuated vaccinal strain of Myxoma virus, in particular the SG33 strain, as an oncolytic agent.
Abstract translation: 本发明涉及使用减毒疫苗菌株的粘液瘤病毒，特别是SG33菌株作为溶瘤剂。
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公开(公告)号：US20120141427A1
公开(公告)日：2012-06-07
申请号：US13377386
申请日：2010-06-11
Applicant: Stéphane Bertagnoli , Magalie Gretillat , Jacqueline Gelfi , Christelle Camus-Bouclainville
Inventor： Stéphane Bertagnoli , Magalie Gretillat , Jacqueline Gelfi , Christelle Camus-Bouclainville
CPC classification number: A61K35/761 , C12N2710/24032
Abstract: The invention relates to the use of an attenuated vaccinal strain of Myxoma virus, in particular the SG33 strain, as an oncolytic agent.
Abstract translation: 本发明涉及使用减毒疫苗菌株的粘液瘤病毒，特别是SG33菌株作为溶瘤剂。
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