公开(公告)号：US08075910B2

公开(公告)日：2011-12-13

申请号：US11040953

申请日：2005-01-21

Applicant: Jack H. Schramm ,  James W. McGrath, Jr.

Inventor： Jack H. Schramm ,  James W. McGrath, Jr.

IPC: A61K47/00 ,  A61K9/48 ,  A61K9/20

CPC classification number: A23D9/007 ,  A23D7/005 ,  A23L33/11 ,  A23L33/115 ,  A23L33/12 ,  A23L33/15 ,  A23V2002/00 ,  A61K9/02 ,  A61K9/4858 ,  A23V2250/7058 ,  A23V2250/706 ,  A23V2250/1868 ,  A23V2250/7052 ,  A23V2250/187

Abstract: The present invention provides oral dosage compositions, and methods of making thereof, which contain an edible oil, preferably containing an omega-3 fatty acid, and admixed therein one or more water soluble vitamins and/or minerals, for example vitamins B6, B9, and/or B12. The present invention also provides a method of making the composition comprising mixing the edible oil and one or more water-soluble vitamins and/or minerals to form a suspension or emulsion of the water-soluble vitamins and/or minerals in the edible oil. The mixture can be inserted into capsules, gelcaps, or caplets for oral consumption. An additional aspect of the invention is that the edible oil can coat particles of the water-soluble vitamins and/or minerals, which may preferably provide the vitamins and/or minerals improved absorption in the body due to increased resistance to degradation in the acidic environment of the stomach.

Abstract translation: 本发明提供口服剂量组合物及其制备方法，其含有食用油，优选含有ω-3脂肪酸，并在其中混合一种或多种水溶性维生素和/或矿物质，例如维生素B6，B9， 和/或B12。 本发明还提供了一种制备该组合物的方法，包括将食用油与一种或多种水溶性维生素和/或矿物质混合以形成食用油中的水溶性维生素和/或矿物质的悬浮液或乳液。 混合物可以插入胶囊，凝胶胶囊或小帽以口服消费。 本发明的另一方面是，食用油可以涂覆水溶性维生素和/或矿物质的颗粒，其可以优选地提供维生素和/或矿物质在体内由于在酸性环境中增加的降解抗性而改善的吸收 的胃。

公开(公告)号：US20080274175A1

公开(公告)日：2008-11-06

申请号：US11579527

申请日：2005-05-18

Applicant: Jack H. Schramm ,  James W. McGrath

Inventor： Jack H. Schramm ,  James W. McGrath

IPC: A61K9/48 ,  A61K31/20 ,  A61K31/59 ,  A61K31/355 ,  A61K31/714 ,  A61K31/44 ,  A61K31/4985 ,  A61P43/00

CPC classification number: A23D9/007 ,  A23D7/005 ,  A23L33/11 ,  A23L33/115 ,  A23L33/12 ,  A23L33/15 ,  A23V2002/00 ,  A61K9/02 ,  A61K9/4858 ,  A23V2250/7058 ,  A23V2250/706 ,  A23V2250/1868 ,  A23V2250/7052 ,  A23V2250/187

Abstract: The invention provides compositions for an administration to a mammal orally or in a suppository that include one or more edible oils (preferably including one or more omega-3 fatty acids), one or more plant stanols, phytosterols, or esters thereof, and admixed in the one or more edible oils one or more water-soluble vitamins and/or minerals, for example, vitamins B6, B9 and/or B12. The invention also provides a method of making the compositions comprising mixing the foregoing components to form a suspension or emulsion of the vitamins and/or minerals in the edible oils. The mixture can be inserted into hollow soft or hard capsules, gelcaps or caplets. The edible oils can coat particles of the water-soluble vitamins and/or minerals, which may provide them with an improved absorption in the body due to an increased resistance to degradation in the acidic environment of the stomach.

Abstract translation: 本发明提供了口服或栓剂给予哺乳动物的组合物，其包括一种或多种食用油（优选包括一种或多种ω-3脂肪酸），一种或多种植物甾烷醇，植物甾醇或其酯，并混合在 一种或多种食用油一种或多种水溶性维生素和/或矿物质，例如维生素B6，B9和/或B12。 本发明还提供一种制备组合物的方法，包括混合前述组分以形成食用油中的维生素和/或矿物质的悬浮液或乳液。 混合物可以插入中空的软或硬胶囊，胶囊或胶囊。 食用油可以涂覆水溶性维生素和/或矿物质的颗粒，这可能由于在胃的酸性环境中的降解性的增加而使其在体内具有改善的吸收。

公开(公告)号：US08524269B2

公开(公告)日：2013-09-03

申请号：US13290504

申请日：2011-11-07

Applicant: Jack H. Schramm ,  James W. McGrath, Jr.

Inventor： Jack H. Schramm ,  James W. McGrath, Jr.

IPC: A61K47/00 ,  A61K9/48 ,  A61K9/20

CPC classification number: A23D9/007 ,  A23D7/005 ,  A23L33/11 ,  A23L33/115 ,  A23L33/12 ,  A23L33/15 ,  A23V2002/00 ,  A61K9/02 ,  A61K9/4858 ,  A23V2250/7058 ,  A23V2250/706 ,  A23V2250/1868 ,  A23V2250/7052 ,  A23V2250/187

Abstract: The present invention provides oral dosage compositions, and methods of making thereof, which contain an edible oil, preferably containing an omega-3 fatty acid, and admixed therein one or more water soluble vitamins and/or minerals, for example vitamins B6, B9, and/or B12. The present invention also provides a method of making the composition comprising mixing the edible oil and one or more water-soluble vitamins and/or minerals to form a suspension or emulsion of the water-soluble vitamins and/or minerals in the edible oil. The mixture can be inserted into capsules, gelcaps, or caplets for oral consumption. An additional aspect of the invention is that the edible oil can coat particles of the water-soluble vitamins and/or minerals, which may preferably provide the vitamins and/or minerals improved absorption in the body due to increased resistance to degradation in the acidic environment of the stomach.

Abstract translation: 本发明提供口服剂量组合物及其制备方法，其含有食用油，优选含有ω-3脂肪酸，并在其中混合一种或多种水溶性维生素和/或矿物质，例如维生素B6，B9， 和/或B12。 本发明还提供了一种制备该组合物的方法，包括将食用油与一种或多种水溶性维生素和/或矿物质混合以形成食用油中的水溶性维生素和/或矿物质的悬浮液或乳液。 混合物可以插入胶囊，凝胶胶囊或小帽以口服消费。 本发明的另一方面是，食用油可以涂覆水溶性维生素和/或矿物质的颗粒，其可以优选地提供维生素和/或矿物质在体内由于在酸性环境中增加的降解抗性而改善的吸收 的胃。

公开(公告)号：US20120052128A1

公开(公告)日：2012-03-01

申请号：US13290504

申请日：2011-11-07

Applicant: Jack H. Schramm ,  James W. McGrath, JR.

Inventor： Jack H. Schramm ,  James W. McGrath, JR.

IPC: A61K31/202 ,  A23L1/304 ,  A61K31/675 ,  A61P9/00 ,  A61K31/714 ,  A61K9/14 ,  A61P7/00 ,  A23L1/302 ,  A61K31/525

CPC classification number: A23D9/007 ,  A23D7/005 ,  A23L33/11 ,  A23L33/115 ,  A23L33/12 ,  A23L33/15 ,  A23V2002/00 ,  A61K9/02 ,  A61K9/4858 ,  A23V2250/7058 ,  A23V2250/706 ,  A23V2250/1868 ,  A23V2250/7052 ,  A23V2250/187

Abstract: The present invention provides oral dosage compositions, and methods of making thereof, which contain an edible oil, preferably containing an omega-3 fatty acid, and admixed therein one or more water soluble vitamins and/or minerals, for example vitamins B6, B9, and/or B12. The present invention also provides a method of making the composition comprising mixing the edible oil and one or more water-soluble vitamins and/or minerals to form a suspension or emulsion of the water-soluble vitamins and/or minerals in the edible oil. The mixture can be inserted into capsules, gelcaps, or caplets for oral consumption. An additional aspect of the invention is that the edible oil can coat particles of the water-soluble vitamins and/or minerals, which may preferably provide the vitamins and/or minerals improved absorption in the body due to increased resistance to degradation in the acidic environment of the stomach.

Abstract translation: 本发明提供口服剂量组合物及其制备方法，其含有食用油，优选含有ω-3脂肪酸，并在其中混合一种或多种水溶性维生素和/或矿物质，例如维生素B6，B9， 和/或B12。 本发明还提供了一种制备该组合物的方法，包括将食用油与一种或多种水溶性维生素和/或矿物质混合以形成食用油中的水溶性维生素和/或矿物质的悬浮液或乳液。 混合物可以插入胶囊，凝胶胶囊或小帽以口服消费。 本发明的另一方面是，食用油可以涂覆水溶性维生素和/或矿物质的颗粒，其可以优选地提供维生素和/或矿物质在体内由于在酸性环境中增加的降解抗性而改善的吸收 的胃。

公开(公告)号：US06576253B2

公开(公告)日：2003-06-10

申请号：US10078814

申请日：2002-02-19

Applicant: Paul B. Manning ,  Jack H. Schramm ,  James W. McGrath, Jr.

Inventor： Paul B. Manning ,  Jack H. Schramm ,  James W. McGrath, Jr.

IPC: A61K4700

CPC classification number: A23G3/368 ,  A23L33/40 ,  A23V2002/00 ,  A23V2250/702 ,  A23V2250/704 ,  A23V2250/708 ,  A23V2250/71 ,  A23V2250/712 ,  A23V2250/156 ,  A23V2250/1868 ,  A23V2250/54252 ,  A23V2250/70 ,  A23V2250/64 ,  A23V2250/5114 ,  A23V2250/194

Abstract: The present invention provides food bars for consumption by pregnant women, lactating women or women of childbearing potential that are attempting to become pregnant containing one or more vitamins and/or minerals, DHA, one or more DHA taste-masking agents and, optionally, one or more anti-constipation and regularity-maintaining agents, methods for preparing these food bars, and methods for supplementing the dietary requirements of pregnant women, lactating women or women of childbearing potential that are attempting to become pregnant. The food bars of the invention generally comprise one or more vitamins and minerals recommended for consumption by pregnant women, lactating women or women of childbearing potential that are attempting to become pregnant in an amount that is effective for enhancing the nutrition of pregnant women, lactating women or women of childbearing potential that are attempting to become pregnant, and that is not harmful to developing fetuses or breast-feeding babies, including calcium in an amount above 1,000 mg, DHA in an amount that is effective for providing, or increasing the supply of, DHA to a developing fetus or baby through a placenta or breast milk, one or more DHA taste-masking agents in an amount that is effective for masking the taste of DHA, and that is not harmful to developing fetuses or breast-feeding babies and, optionally, one or more anti-constipation and regularity-maintaining agents in an amount that is effective for reducing or eliminating constipation, and that is not harmful to developing fetuses or breast-feeding babies, from about 0 to about 99 weight percent of carbohydrates, from about 0 to about 80 weight percent of proteins, and from about 0 to about 60 weight percent of fats.

公开(公告)号：US08173160B2

公开(公告)日：2012-05-08

申请号：US11579527

申请日：2005-05-18

Applicant: Jack H. Schramm ,  James W. McGrath, Jr.

Inventor： Jack H. Schramm ,  James W. McGrath, Jr.

IPC: A61K9/48 ,  A61K31/20 ,  A61K31/59 ,  A61K31/355 ,  A61K31/714 ,  A61K31/44 ,  A61K31/4985 ,  A61P43/00

CPC classification number: A23D9/007 ,  A23D7/005 ,  A23L33/11 ,  A23L33/115 ,  A23L33/12 ,  A23L33/15 ,  A23V2002/00 ,  A61K9/02 ,  A61K9/4858 ,  A23V2250/7058 ,  A23V2250/706 ,  A23V2250/1868 ,  A23V2250/7052 ,  A23V2250/187

Abstract: The invention provides compositions for an administration to a mammal orally or in a suppository that include one or more edible oils (preferably including one or more omega-3 fatty acids), one or more plant stanols, phytosterols, or esters thereof, and admixed in the one or more edible oils one or more water-soluble vitamins and/or minerals, for example, vitamins B6, B9 and/or B12. The invention also provides a method of making the compositions comprising mixing the foregoing components to form a suspension or emulsion of the vitamins and/or minerals in the edible oils. The mixture can be inserted into hollow soft or hard capsules, gelcaps or caplets. The edible oils can coat particles of the water-soluble vitamins and/or minerals, which may provide them with an improved absorption in the body due to an increased resistance to degradation in the acidic environment of the stomach.

Abstract translation: 本发明提供了口服或栓剂给予哺乳动物的组合物，其包括一种或多种食用油（优选包括一种或多种ω-3脂肪酸），一种或多种植物甾烷醇，植物甾醇或其酯，并混合在 一种或多种食用油一种或多种水溶性维生素和/或矿物质，例如维生素B6，B9和/或B12。 本发明还提供一种制备组合物的方法，包括混合前述组分以形成食用油中的维生素和/或矿物质的悬浮液或乳液。 混合物可以插入中空的软或硬胶囊，胶囊或胶囊。 食用油可以涂覆水溶性维生素和/或矿物质的颗粒，这可能由于在胃的酸性环境中的降解性的增加而使其在体内具有改善的吸收。

公开(公告)号：US06569445B2

公开(公告)日：2003-05-27

申请号：US09730194

申请日：2000-12-05

Applicant: Paul B. Manning ,  Jack H. Schramm ,  James W. McGrath, Jr.

Inventor： Paul B. Manning ,  Jack H. Schramm ,  James W. McGrath, Jr.

IPC: A61K4700

CPC classification number: A23G3/368 ,  A23L33/40 ,  A23V2002/00 ,  A23V2250/702 ,  A23V2250/704 ,  A23V2250/708 ,  A23V2250/71 ,  A23V2250/712 ,  A23V2250/156 ,  A23V2250/1868 ,  A23V2250/54252 ,  A23V2250/70 ,  A23V2250/64 ,  A23V2250/5114 ,  A23V2250/194

Abstract: The present invention provides food bars for consumption by pregnant women, lactating women or women of childbearing potential that are attempting to become pregnant containing one or more vitamins and/or minerals, and one or more anti-constipation and regularity-maintaining agents, methods for preparing these food bars, and methods for supplementing the dietary requirements of pregnant women, lactating women or women of childbearing potential that are attempting to become pregnant. The food bars of the invention generally comprise one or more vitamins and minerals recommended for consumption by pregnant women, lactating women or women of childbearing potential that are attempting to become pregnant in an amount that is effective for enhancing the nutrition of pregnant women, lactating women or women of childbearing potential that are attempting to become pregnant, and that is not harmful to developing fetuses or breast-feeding babies, one or more anti-constipation and regularity-maintaining agents in an amount that is effective for reducing or eliminating constipation, and that is not harmful to developing fetuses or breast-feeding babies, from about 0 to about 99 weight percent of carbohydrates, from about 0 to about 80 weight percent of proteins, and from about 0 to about 60 weight percent of fats.

Abstract translation: 本发明提供了孕妇，哺乳期妇女或试图怀孕含有一种或多种维生素和/或矿物质的怀孕潜力妇女和一种或多种抗便秘和规律性维持剂的食物棒，用于 准备这些食物棒，以及补充孕妇，哺乳期妇女或试图怀孕的生育潜力的妇女的饮食要求的方法。 本发明的食物棒通常包含一种或多种建议用于怀孕妇女，哺乳期妇女或试图怀孕的育龄妇女消费的维生素和矿物质，其量有助于增加孕妇的营养，哺乳期妇女 或试图怀孕的生育潜力的妇女，对发育中的胎儿或哺乳婴儿，一种或多种有效减少或消除便秘的抗便秘和规律性维持剂无害，并且 对发育中的胎儿或母乳喂养婴儿无害，约0至约99重量％的碳水化合物，约0至约80重量％的蛋白质和约0至约60重量％的脂肪。