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公开(公告)号：US08183243B2
公开(公告)日：2012-05-22
申请号：US13158920
申请日：2011-06-13
Applicant: Koo Lee , Sang Dae Lee , Sang Pil Moon , In Ae Ahn , Sung Pil Choi , Hyun Ho Lee , Dong Sup Shim , Soo Yong Chung , Hyun Min Lee
Inventor： Koo Lee , Sang Dae Lee , Sang Pil Moon , In Ae Ahn , Sung Pil Choi , Hyun Ho Lee , Dong Sup Shim , Soo Yong Chung , Hyun Min Lee
IPC: C07D405/14
CPC classification number: C07D417/14 , A61K31/4025 , A61K31/496 , C07D207/16 , C07D401/14 , C07D403/06 , C07D405/14 , C07D409/14
Abstract: The present invention relates to a compound having a good agonistic activity to melanocortin receptor, or pharmaceutically acceptable salt or isomer thereof, and an agonistic composition for melanocortin receptor comprising the same as an active ingredient.
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公开(公告)号：US20110237795A1
公开(公告)日：2011-09-29
申请号：US13158734
申请日：2011-06-13
Applicant: Koo Lee , Sang Dae Lee , Sang Pil Moon , In Ae Ahn , Sung Pil Choi , Hyun Ho Lee , Dong Sup Shim , Soo Yong Chung , Hyun Min Lee
Inventor： Koo Lee , Sang Dae Lee , Sang Pil Moon , In Ae Ahn , Sung Pil Choi , Hyun Ho Lee , Dong Sup Shim , Soo Yong Chung , Hyun Min Lee
IPC: C07D403/14
CPC classification number: C07D417/14 , A61K31/4025 , A61K31/496 , C07D207/16 , C07D401/14 , C07D403/06 , C07D405/14 , C07D409/14
Abstract: The present invention relates to a compound having a good agonistic activity to melanocortin receptor, or pharmaceutically acceptable salt or isomer thereof, and an agonistic composition for melanocortin receptor comprising the same as an active ingredient.
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3.发明授权Imidazole derivatives having an inhibitory activity for farnesyl transferase and process for preparation thereof 失效具有法呢基转移酶抑制活性的咪唑衍生物及其制备方法公开(公告)号：US06268363B1
公开(公告)日：2001-07-31
申请号：US09554646
申请日：2000-05-17
Applicant: Hyun Il Lee , Jong Sung Koh , Jin Ho Lee , Won Hee Jung , You Seung Shin , Hyun Ho Chung , Jong Hyun Kim , Seong Gu Ro , Tae Saeng Choi , Shin Wu Jeong , Tae Hwan Kwak , In Ae Ahn , Hyun Sung Kim , Sun Hwa Lee , Kwi Hwa Kim , Jung Kwon Yoo
Inventor： Hyun Il Lee , Jong Sung Koh , Jin Ho Lee , Won Hee Jung , You Seung Shin , Hyun Ho Chung , Jong Hyun Kim , Seong Gu Ro , Tae Saeng Choi , Shin Wu Jeong , Tae Hwan Kwak , In Ae Ahn , Hyun Sung Kim , Sun Hwa Lee , Kwi Hwa Kim , Jung Kwon Yoo
IPC: A61K314178
CPC classification number: C07D401/14 , C07D403/06 , C07D405/14 , C07D413/06 , C07D417/06 , C07D417/14
Abstract: The present invention relates to a novel imidazole derivative represented by formula (1) which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts or isomers thereof, in which A, n1 and Y are defined in the specification; to a process for preparation of the compound of formula (1); to intermediates which are used in the preparation of the compound of formula (1); and to a pharmaceutical composition comprising the compound of formula (1) as an active ingredient.
Abstract translation: 本发明涉及式（1）所示的新型咪唑衍生物，其表现出对法呢基转移酶的抑制活性或其药学上可接受的盐或异构体，其中A，n1和Y在本说明书中定义; 涉及制备式（1）化合物的方法; 用于制备式（1）化合物的中间体; 以及包含式（1）化合物作为活性成分的药物组合物。
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公开(公告)号：US20090298829A1
公开(公告)日：2009-12-03
申请号：US12305935
申请日：2007-07-13
Applicant: Sung Pil Choi , In Ae Ahn , Sang Hyup Lee , Sang Dae Lee , Mi Sook Shin , Koo Lee , Deog Young Choi , Dong Sup Shim , Hyeon Joo Yim , Min Kyung Yoon , Soo Yong Chung , Jung Ae Lee , Yong Hwa Ha , Young Kwan Kim , Oeuk Park , Hyun Min Lee , Youn Hoa Kim
Inventor： Sung Pil Choi , In Ae Ahn , Sang Hyup Lee , Sang Dae Lee , Mi Sook Shin , Koo Lee , Deog Young Choi , Dong Sup Shim , Hyeon Joo Yim , Min Kyung Yoon , Soo Yong Chung , Jung Ae Lee , Yong Hwa Ha , Young Kwan Kim , Oeuk Park , Hyun Min Lee , Youn Hoa Kim
IPC: A61K31/4025 , C07D401/06 , C07D413/14 , A61K31/5377 , A61P3/04 , A61P3/10 , A61P29/00 , A61P15/00
CPC classification number: C07D207/16 , C07D207/48 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
Abstract: The present invention relates to a compound of the following formula 1, pharmaceutically acceptable salt and isomer thereof effective as agonist of melanocortin receptor, and an agonistic composition of melanocortin receptor comprising the same as active ingredient.
Abstract translation: 本发明涉及有效作为黑皮质素受体激动剂的下式1化合物，其药学上可接受的盐和异构体，以及包含与活性成分相同的黑皮质素受体激动剂组合物。
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公开(公告)号：US20110224219A1
公开(公告)日：2011-09-15
申请号：US13128725
申请日：2009-11-10
Applicant: Koo Lee , Sang Dae Lee , Sang Pil Moon , In Ae Ahn , Sung Pil Choi , Hyun Ho Lee , Dong Sup Shim , Soo Yong Chung , Hyun Min Lee
Inventor： Koo Lee , Sang Dae Lee , Sang Pil Moon , In Ae Ahn , Sung Pil Choi , Hyun Ho Lee , Dong Sup Shim , Soo Yong Chung , Hyun Min Lee
IPC: A61K31/501 , C07D403/14 , A61K31/497 , A61P15/10 , A61P3/04
CPC classification number: C07D417/14 , A61K31/4025 , A61K31/496 , C07D207/16 , C07D401/14 , C07D403/06 , C07D405/14 , C07D409/14
Abstract: The present invention relates to a compound having a good agonistic activity to melanocortin receptor, or pharmaceutically acceptable salt or isomer thereof, and an agonistic composition for melanocortin receptor comprising the same as an active ingredient.
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Patent Agency Ranking
公开(公告)号：US20070129346A1
公开(公告)日：2007-06-07
申请号：US10579042
申请日：2004-11-12
Applicant: Koo Lee , Heui-Sul Park , In-Ae Ahn , Hyun-Ju Yoo , Jong-Yup Kim , Deog-Young Choi , Hyeon-Joo Yim , Kyung-Ha Chung , Dong-Sup Shim , Sang-Kyun Lee , Yutaka Kondoh , Ryoji Hirabayashi , Shugo Honda , Hidetaka Kaku , Jun-ichi Shishikura , Hiroyuki Ito , Takeshi Kurama
Inventor： Koo Lee , Heui-Sul Park , In-Ae Ahn , Hyun-Ju Yoo , Jong-Yup Kim , Deog-Young Choi , Hyeon-Joo Yim , Kyung-Ha Chung , Dong-Sup Shim , Sang-Kyun Lee , Yutaka Kondoh , Ryoji Hirabayashi , Shugo Honda , Hidetaka Kaku , Jun-ichi Shishikura , Hiroyuki Ito , Takeshi Kurama
IPC: A61K31/397 , A61K31/401 , A61K31/445 , C07D211/06
CPC classification number: C04B35/632 , C07D205/04 , C07D207/14 , C07D211/58 , C07D401/12 , C07D403/12 , C07D405/12
Abstract: The present invention relates a compound of formula 1, and pharmaceutically acceptable salt, hydrate, solvate, or isomer thereof effective as agonist of melanocortin receptor, and an agonistic composition of melanocortin receptor comprising the same as active ingredient.
Abstract translation: 本发明涉及有效作为黑皮质素受体激动剂的式1化合物及其药学上可接受的盐，水合物，溶剂化物或异构体，以及包含与活性成分相同的黑皮质素受体激动剂组合物。
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公开(公告)号：US08288386B2
公开(公告)日：2012-10-16
申请号：US13128725
申请日：2009-11-10
Applicant: Koo Lee , Sang Dae Lee , Sang Pil Moon , In Ae Ahn , Sung Pil Choi , Hyun Ho Lee , Dong Sup Shim , Soo Yong Chung , Hyun Min Lee
Inventor： Koo Lee , Sang Dae Lee , Sang Pil Moon , In Ae Ahn , Sung Pil Choi , Hyun Ho Lee , Dong Sup Shim , Soo Yong Chung , Hyun Min Lee
IPC: A61K31/496 , A61K31/501 , A61K31/506 , C07D401/14 , C07D403/06 , C07D403/14 , C07D405/14 , C07D417/14
CPC classification number: C07D417/14 , A61K31/4025 , A61K31/496 , C07D207/16 , C07D401/14 , C07D403/06 , C07D405/14 , C07D409/14
Abstract: The present invention relates to a compound having a good agonistic activity to melanocortin receptor, or pharmaceutically acceptable salt or isomer thereof, and an agonistic composition for melanocortin receptor comprising the same as an active ingredient.
Abstract translation: 本发明涉及对黑皮质素受体或其药学上可接受的盐或异构体具有良好的激动作用的化合物和包含其作为活性成分的黑皮质素受体激动剂组合物。
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公开(公告)号：US08236955B2
公开(公告)日：2012-08-07
申请号：US13158734
申请日：2011-06-13
Applicant: Koo Lee , Sang Dae Lee , Sang Pil Moon , In Ae Ahn , Sung Pil Choi , Hyun Ho Lee , Dong Sup Shim , Soo Yong Chung , Hyun Min Lee
Inventor： Koo Lee , Sang Dae Lee , Sang Pil Moon , In Ae Ahn , Sung Pil Choi , Hyun Ho Lee , Dong Sup Shim , Soo Yong Chung , Hyun Min Lee
IPC: C07D403/06
CPC classification number: C07D417/14 , A61K31/4025 , A61K31/496 , C07D207/16 , C07D401/14 , C07D403/06 , C07D405/14 , C07D409/14
Abstract: The present invention relates to a compound having a good agonistic activity to melanocortin receptor, or pharmaceutically acceptable salt or isomer thereof, and an agonistic composition for melanocortin receptor comprising the same as an active ingredient.
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公开(公告)号：US20110245500A1
公开(公告)日：2011-10-06
申请号：US13158920
申请日：2011-06-13
Applicant: Koo Lee , Sang Dae Lee , Sang Pil Moon , In Ae Ahn , Sung Pil Choi , Hyun Ho Lee , Dong Sup Shim , Soo Yong Chung , Hyun Min Lee
Inventor： Koo Lee , Sang Dae Lee , Sang Pil Moon , In Ae Ahn , Sung Pil Choi , Hyun Ho Lee , Dong Sup Shim , Soo Yong Chung , Hyun Min Lee
IPC: C07D405/14
CPC classification number: C07D417/14 , A61K31/4025 , A61K31/496 , C07D207/16 , C07D401/14 , C07D403/06 , C07D405/14 , C07D409/14
Abstract: The present invention relates to a compound having a good agonistic activity to melanocortin receptor, or pharmaceutically acceptable salt or isomer thereof, and an agonistic composition for melanocortin receptor comprising the same as an active ingredient.
Abstract translation: 本发明涉及对黑皮质素受体或其药学上可接受的盐或异构体具有良好的激动作用的化合物和包含其作为活性成分的黑皮质素受体激动剂组合物。
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公开(公告)号：US07879852B2
公开(公告)日：2011-02-01
申请号：US12305935
申请日：2007-07-13
Applicant: Sung Pil Choi , In Ae Ahn , Sang Hyup Lee , Sang Dae Lee , Mi Sook Shin , Koo Lee , Deog Young Choi , Dong Sup Shim , Hyeon Joo Yim , Min Kyung Yoon , Soo Yong Chung , Jung Ae Lee , Yong Hwa Ha , Young Kwan Kim , Oeuk Park , Hyun Min Lee , Youn Hoa Kim
Inventor： Sung Pil Choi , In Ae Ahn , Sang Hyup Lee , Sang Dae Lee , Mi Sook Shin , Koo Lee , Deog Young Choi , Dong Sup Shim , Hyeon Joo Yim , Min Kyung Yoon , Soo Yong Chung , Jung Ae Lee , Yong Hwa Ha , Young Kwan Kim , Oeuk Park , Hyun Min Lee , Youn Hoa Kim
IPC: A61K31/401 , A61K31/4025 , A61K31/422 , A61K31/427 , A61K31/4439 , A61K31/5377 , C07D207/14 , C07D213/72 , C07D263/48 , C07D277/54 , C07D295/28
CPC classification number: C07D207/16 , C07D207/48 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
Abstract: The present invention relates to a compound of the following formula 1, pharmaceutically acceptable salt and isomer thereof effective as agonist of melanocortin receptor, and an agonistic composition of melanocortin receptor comprising the same as active ingredient.
Abstract translation: 本发明涉及有效作为黑皮质素受体激动剂的下式1化合物，其药学上可接受的盐和异构体，以及包含与活性成分相同的黑皮质素受体激动剂组合物。
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