ENGINEERED VACCINIA VIRUS
    1.
    发明申请

    公开(公告)号:US20220257756A1

    公开(公告)日:2022-08-18

    申请号:US17626288

    申请日:2020-07-13

    发明人: Ming YUAN

    摘要: An engineered vaccinia virus, a pharmaceutical composition containing the same, and methods for use in treating a subject in need using the same are provided. The engineered vaccinia virus includes a mutated viral sequence and a heterologous sequence. The mutated viral sequence is used for selective replication in tumor cells and/or activation of immune cells. The heterologous sequence encodes an immune co-stimulatory pathway activating molecule, immunomodulator gene, a truncated viral envelope gene, and/or a tumor suppressor. The heterologous sequence is stably incorporated into the genome of the engineered vaccinia virus. The pharmaceutical composition includes an effective amount of the engineered vaccinia virus and a pharmaceutical acceptable vehicle. The methods for use in treating the subject in need include administering the engineered vaccinia virus to the subject.

    CONNECTOR HAVING IMPROVED INSULATIVE HOUSING
    2.
    发明申请
    CONNECTOR HAVING IMPROVED INSULATIVE HOUSING 有权
    具有改进绝缘外壳的连接器

    公开(公告)号:US20120009811A1

    公开(公告)日:2012-01-12

    申请号:US13088431

    申请日:2011-04-18

    IPC分类号: H01R13/648 H01R13/62

    CPC分类号: H01R13/6581 H01R13/5045

    摘要: A connector (100) includes an insulative housing (1), a set of contacts (3) attached to the insulative housing, and a metal shell shielding the insulative housing. The insulative housing has a base portion (11) and a tongue potion (12) extending forwardly from the base portion. The base portion has a pair of first bumps (1124) protruding therefrom and located at two sides thereof, and a second bumps (1125) protruding therefrom and located between the first bumps. The metal shell has a pair of first notches (44) locating at two sides thereof and locking with the first bumps, and a second notch (45) located between the first notches and locking with the second bumps.

    摘要翻译: 连接器(100)包括绝缘壳体(1),附接到绝缘壳体的一组触头(3)和屏蔽绝缘壳体的金属壳体。 绝缘壳体具有从基部向前延伸的基部(11)和舌部(12)。 基部具有从其两侧突出的一对第一凸起(1124)和从其突出并位于第一凸块之间的第二凸块(1125)。 金属外壳具有位于其两侧并与第一凸起锁定的一对第一凹口(44)和位于第一凹口之间并与第二凸块锁定的第二凹口(45)。

    OVERHEAD SHOWER WITH LCD
    3.
    发明申请
    OVERHEAD SHOWER WITH LCD 审中-公开
    带LCD的超大淋浴

    公开(公告)号:US20110210188A1

    公开(公告)日:2011-09-01

    申请号:US13127563

    申请日:2009-11-27

    申请人: Hua Yao Xianguo Zou

    发明人: Hua Yao Xianguo Zou

    IPC分类号: B67D7/08

    摘要: An overhead shower with LCD, has a water outlet device connected with the main body of the shower. A hydroelectric device and a thermistance are disposed in the main body. A display module connected with one side of the main body has a circuit board and an LCD screen which are electrically connected with the hydroelectric device and the thermistance. When water flows into the main body, the hydroelectric device supplies power for display module, and the thermistance transmits the temperature information to the display module, so that the temperature is shown on the LCD screen. Therefore the outflow temperature is shown on the LCD screen so that the user can clearly read the outflow temperature of the shower.

    摘要翻译: 带有液晶显示器的顶置式淋浴器,具有与淋浴器主体连接的出水装置。 水力发电装置和热电偶设置在主体中。 与主体一侧连接的显示模块具有与水力发电装置电连接的电路基板和液晶显示屏。 当水流入主体时,水力发电装置供给显示模块的电力,并且电阻将温度信息传送到显示模块,使得温度显示在LCD屏幕上。 因此,液晶显示屏上显示流出温度,使用户可以清楚地读取淋浴液的流出温度。

    SHOWER FIXING SEAT WITH LCD
    4.
    发明申请
    SHOWER FIXING SEAT WITH LCD 失效
    淋浴固定座椅带LCD

    公开(公告)号:US20110209782A1

    公开(公告)日:2011-09-01

    申请号:US13127064

    申请日:2009-11-27

    申请人: Hua Yao

    发明人: Hua Yao

    IPC分类号: F16K37/00

    摘要: Shower fixing seat with LCD has a fixing seat fixed on the front end of its main body. The rear end of the main body is a water inlet connected with a water supply pipe. The lower end of the main body is a water outlet connected with the flexible pipe of the shower head. A hydroelectric device and a thermistance are disposed in the main body. A display module connected with one side of the main body has a circuit board and an LCD screen which are electrically connected to the hydroelectric device and the thermistance. When water flows into the main body, the hydroelectric device supplies power for the display module, and the thermistance transmits the temperature information to the display module so that the temperature is shown on the LCD screen. The shower fixing seat shows the shower outflow temperature.

    摘要翻译: 具有LCD的淋浴固定座具有固定在其主体前端的固定座。 主体的后端是与供水管连接的进水口。 主体的下端是与淋浴喷头的柔性管连接的出水口。 水力发电装置和热电偶设置在主体中。 与本体的一侧连接的显示模块具有电连接到水力发电装置和电阻的电路板和LCD屏。 当水流入主体时,水力发电装置为显示模块供电,并且电阻将温度信息传送到显示模块,使温度显示在LCD屏幕上。 淋浴固定座显示淋浴液流出温度。

    Power socket with anti-mismating means
    5.
    发明授权
    Power socket with anti-mismating means 有权
    电源插座采用防错误方式

    公开(公告)号:US07927108B2

    公开(公告)日:2011-04-19

    申请号:US12606205

    申请日:2009-10-27

    IPC分类号: H01R12/20

    摘要: A power socket (100) includes an insulative housing (1), a first contact (21) and a plurality of second contacts (22) attached to the insulative housing (1) and means (185); the insulative housing (1) defines an annular first groove (16) and a first cylinder (18) disposed within the first groove (16); the first groove (16) defines a first inner surface (161) and a first outer surface (162); the first cylinder (18) defines a first passageway (181) extending through a center portion thereof along the front to back direction; the first contact (21) has a first contact portion (211) extending into the first passageway (181); each second contact (22) has a second contact portion (221) extending into the first groove (16); the means (185) extending into the first groove (16) for preventing a familiar round power plug from being inserted into the first groove (16).

    摘要翻译: 电源插座(100)包括绝缘壳体(1),第一触点(21)和附接到绝缘壳体(1)的多个第二触点(22)和装置(185); 所述绝缘壳体(1)限定环形第一槽(16)和设置在所述第一槽(16)内的第一缸体(18)。 第一凹槽(16)限定第一内表面(161)和第一外表面(162); 第一气缸(18)限定沿其前后方向延伸穿过其中心部分的第一通道(181) 第一接触件(21)具有延伸到第一通道(181)中的第一接触部分(211)。 每个第二触点(22)具有延伸到第一凹槽(16)中的第二接触部分(221); 所述装置(185)延伸到所述第一凹槽(16)中,用于防止熟悉的圆形电源插头插入到所述第一凹槽(16)中。

    Stacked electronical connector
    6.
    发明授权
    Stacked electronical connector 失效
    堆叠电子连接器

    公开(公告)号:US07841894B2

    公开(公告)日:2010-11-30

    申请号:US12387081

    申请日:2009-04-28

    IPC分类号: H01R13/60

    CPC分类号: H01R27/02 H01R12/712

    摘要: A stacked electrical connector (1) includes an insulative housing (2) and a number of contacts (3) retained in the insulative housing (2). The insulative housing (2) includes a first housing (21) and a second housing (22) arranged in an up-to-down direction. The first housing (21) defining a number of inserting ports (213) recessed from a front end thereof. The second housing (22) defines a receiving space (224) to receive a standard USB 2.0 B type plug. The contacts (3) include a number of first contacts (31) retained in the first housing (21) and a number of second contacts (32) retained in the second housing (22). Each first contact (31) has a first contact portion (311) extending into the inserting port (213). Each second contact (32) has a second contact portion (321) and a second soldering portion (324) being arranged in a row in a level direction.

    摘要翻译: 堆叠的电连接器(1)包括绝缘壳体(2)和保持在绝缘壳体(2)中的多个触点(3)。 绝缘壳体(2)包括沿上下方向布置的第一壳体(21)和第二壳体(22)。 第一壳体(21)限定从其前端凹入的多个插入口(213)。 第二壳体(22)限定接收标准USB 2.0 B型插头的接收空间(224)。 触点(3)包括保持在第一壳体(21)中的多个第一触头(31)和保持在第二壳体(22)中的多个第二触头(32)。 每个第一触点(31)具有延伸到插入口(213)中的第一接触部分(311)。 每个第二触点(32)具有沿着水平方向排成一行的第二接触部分(321)和第二焊接部分(324)。

    Stacked electrical connector with improved shell for EMI protection
    7.
    发明授权
    Stacked electrical connector with improved shell for EMI protection 失效
    堆叠电连接器,具有改进的外壳,用于EMI保护

    公开(公告)号:US07758380B2

    公开(公告)日:2010-07-20

    申请号:US12466356

    申请日:2009-05-14

    IPC分类号: H01R13/648

    摘要: A stacked electrical connector includes an upper mating port, a lower mating port, an insulative separate portion separating the upper and the lower mating ports, and an additional metal shell covering the separate portion. The upper and lower mating ports include first and second metal shells, respectively. The additional metal shell includes a main body shielding a front surface of the separate portion and a pair of side walls extending backwardly from the main body to abut against the opposite walls. At least one side wall includes a lower bending portion attached to the second metal shell in order to form a much larger grounding area for Electromagnetic Interference (EMI) protection.

    摘要翻译: 堆叠的电连接器包括上配合端口,下配合端口,分离上配合端口和下配合端口的绝缘分离部分,以及覆盖分离部分的附加金属外壳。 上下配合端口分别包括第一和第二金属壳。 附加的金属壳包括屏蔽分离部分的前表面的主体和从主体向后延伸以抵靠相对的壁的一对侧壁。 至少一个侧壁包括附接到第二金属壳的下弯曲部分,以便形成用于电磁干扰(EMI)保护的更大的接地面积。

    Stacked electrical connector with improved contacts arrangement
    8.
    发明授权
    Stacked electrical connector with improved contacts arrangement 失效
    具有改进触点布置的堆叠电连接器

    公开(公告)号:US07753724B2

    公开(公告)日:2010-07-13

    申请号:US12387281

    申请日:2009-04-30

    IPC分类号: H01R13/66

    摘要: A stacked electrical connector includes a front mating face, an insulative housing comprising and a plurality of contacts. The insulative housing has a first housing and a second housing arranged in an up-to-down direction. The first housing defines a plurality of inserting ports. The second housing defines a receiving space. The contacts include a plurality of first contacts and second contacts. The first contacts each has a first contact portion extending into the inserting port and a first soldering tail extending out of the insulative housing downwardly. The second contacts each has a second contact portion extending into the receiving space and a second soldering tail extending out of the insulative housing downwardly. All the first soldering tails are arranged closer to the mating face than the second soldering tails.

    摘要翻译: 堆叠的电连接器包括前配合面,绝缘壳体和多个触点。 绝缘壳体具有沿上下方向布置的第一壳体和第二壳体。 第一壳体限定多个插入口。 第二壳体限定接收空间。 触点包括多个第一触点和第二触点。 第一触头各自具有延伸到插入口中的第一接触部分和从绝缘壳体向下延伸出的第一焊接尾部。 第二触头各自具有延伸到接收空间中的第二接触部分和从绝缘壳体向下延伸出的第二焊接尾部。 所有的第一个焊接尾部布置成比第二个焊接尾部更靠近配合面。

    POWER SOCKET WITH ANTI-MISMATING MEANS
    9.
    发明申请
    POWER SOCKET WITH ANTI-MISMATING MEANS 有权
    电源插座具有防误报

    公开(公告)号:US20100105226A1

    公开(公告)日:2010-04-29

    申请号:US12606205

    申请日:2009-10-27

    IPC分类号: H01R13/44

    摘要: A power socket (100) includes an insulative housing (1), a first contact (21) and a plurality of second contacts (22) attached to the insulative housing (1) and means (185); the insulative housing (1) defines an annular first groove (16) and a first cylinder (18) disposed within the first groove (16); the first groove (16) defines a first inner surface (161) and a first outer surface (162); the first cylinder (18) defines a first passageway (181) extending through a centre portion thereof along the front to back direction; the first contact (21) has a first contact portion (211) extending into the first passageway (181); each second contact (22) has a second contact portion (221) extending into the first groove (16); the means (185) extending into the first groove (16) for preventing a familiar round power plug from being inserted into the first groove (16).

    摘要翻译: 电源插座(100)包括绝缘壳体(1),第一触点(21)和附接到绝缘壳体(1)的多个第二触点(22)和装置(185); 所述绝缘壳体(1)限定环形第一槽(16)和设置在所述第一槽(16)内的第一缸体(18)。 第一凹槽(16)限定第一内表面(161)和第一外表面(162); 第一气缸(18)限定沿其前后方向延伸穿过其中心部分的第一通道(181) 第一接触件(21)具有延伸到第一通道(181)中的第一接触部分(211)。 每个第二触点(22)具有延伸到第一凹槽(16)中的第二接触部分(221); 所述装置(185)延伸到所述第一凹槽(16)中,用于防止熟悉的圆形电源插头插入到所述第一凹槽(16)中。

    Voltage regulator for semiconductor memory
    10.
    发明授权
    Voltage regulator for semiconductor memory 有权
    用于半导体存储器的稳压器

    公开(公告)号:US07577043B2

    公开(公告)日:2009-08-18

    申请号:US11953077

    申请日:2007-12-10

    IPC分类号: G11C16/04

    CPC分类号: G11C5/147

    摘要: A voltage regulator in a semiconductor memory has: a comparing unit including first and second bias current sources, for comparing an output voltage with first and second reference voltages under control of a first signal, the second bias current source being ON under control of a second signal; and a driver active element, coupled to the comparing unit, for outputting the output voltage. Before sensing operations, the output voltage is reset to the second reference voltage. During the sensing operations, the output voltage is maintained at the first reference voltage and the second signal is asserted for turning ON the second bias current source for raising speed of the comparing unit. After the sensing operations, the output voltage is reset to the second reference voltage.

    摘要翻译: 半导体存储器中的稳压器具有:包括第一和第二偏置电流源的比较单元,用于在第一信号的控制下将输出电压与第一和第二参考电压进行比较,第二偏置电流源在第二 信号; 以及耦合到比较单元的用于输出输出电压的驱动器有源元件。 在感测操作之前,输出电压被复位到第二个参考电压。 在感测操作期间,输出电压保持在第一参考电压,并且第二信号被断言以接通第二偏置电流源以提高比较单元的速度。 在感测操作之后,输出电压被复位到第二参考电压。