公开(公告)号：US20120034250A1

公开(公告)日：2012-02-09

申请号：US13264008

申请日：2010-04-13

申请人： Shohei Shirakami ,  Yutaka Nakajima ,  Jun Maeda ,  Hiroaki Tominaga ,  Hiroaki Yamagishi ,  Takeshi Hondo ,  Masamichi Inami ,  Hiroki Morio ,  Takayuki Inoue ,  Tsuyoshi Mizutani ,  Hiroki Ishioka

发明人： Shohei Shirakami ,  Yutaka Nakajima ,  Jun Maeda ,  Hiroaki Tominaga ,  Hiroaki Yamagishi ,  Takeshi Hondo ,  Masamichi Inami ,  Hiroki Morio ,  Takayuki Inoue ,  Tsuyoshi Mizutani ,  Hiroki Ishioka

IPC分类号： A61K31/437 ,  A61K31/55 ,  A61P37/06 ,  A61K31/541 ,  A61K31/5377 ,  A61K31/496 ,  C07D471/14 ,  A61K31/497

CPC分类号： C07D471/14 ,  C07D519/00

摘要： [Problem]The present invention provides a condensed pyrrolopyridine derivative which is useful as an active ingredient for a pharmaceutical composition, in particular, a pharmaceutical composition for preventing or treating diseases caused by undesirable cytokine signal transduction or diseases caused by abnormal cytokine signal transduction.[Means for Solution]The present inventors have extensively studied a compound having a JAK inhibitory action, and as a result, they have found that a condensed pyrrolopyridine derivative which is the compound of the present invention has an excellent JAK inhibitory action, and is therefore useful as an agent for preventing or treating diseases caused by undesirable cytokine signal transduction or diseases caused by abnormal cytokine signal transduction, thereby completing the present invention.

摘要翻译： 本发明提供可用作药物组合物的活性成分的特别是用于预防或治疗由不良细胞因子信号转导引起的疾病或由异常细胞因子信号转导引起的疾病的药物组合物的缩合吡咯并吡啶衍生物。 [解决方案]本发明人广泛研究了具有JAK抑制作用的化合物，结果发现，作为本发明化合物的缩合吡咯并吡啶衍生物具有优异的JAK抑制作用，因此 可用作预防或治疗由不良细胞因子信号转导引起的疾病或由异常细胞因子信号转导引起的疾病的药剂，从而完成本发明。

公开(公告)号：US06813539B2

公开(公告)日：2004-11-02

申请号：US10438189

申请日：2003-05-15

申请人： Tatsuro Morimoto ,  Takashi Matsuura ,  Hiroki Morio ,  Tetsuya Nakamura

发明人： Tatsuro Morimoto ,  Takashi Matsuura ,  Hiroki Morio ,  Tetsuya Nakamura

IPC分类号： G06F700

CPC分类号： G05B19/41865 ,  B23P19/001 ,  B23P21/004 ,  G05B19/41805 ,  G05B2219/31036 ,  G05B2219/32082 ,  Y02P90/04 ,  Y02P90/18 ,  Y02P90/20

摘要： The invention makes it possible to efficiently and accurately supply parts to a work in an assembling production line structured as a mixed assembly line, and to improve a flexibility of changing the line. A parts supplying system of the assembling production line is provided with a working instruction server which takes in a production order information corresponding to an optional number of works, extracts the same type of works in a unit of a lot so as to sort in an order of a parts preparing work, and generates a working instruction information including a parts preparing work order, a number of the lots and an assembly parts information per the types, set containers which receive assembly parts sets to be assembled in one work, a parts setting area which has a working station provided with parts shelves for the assembly parts, and inputs the assembly parts set for the corresponding type of work to each of the set containers in the order of the parts preparing works by a unit of the same type lot, on the basis of the working instruction information, and a replacement buffer which returns each of the set containers from the parts setting area to an order of the type in accordance with the production order in the assembling production line so as to input to the assembling production line.

摘要翻译： 本发明使得可以有效地并且准确地将零件供应到以混合装配线构成的组装生产线中的工件，并且提高了改变生产线的灵活性。 组装生产线的零件供应系统设置有工作指令服务器，其接收与可选数量的作品相对应的生产订单信息，以大量的单位提取相同类型的作品，以便按顺序排序 的零件准备工作，并且生成包括准备工作单的零件，批次的数量和每种类型的装配零件信息的工作指令信息，设置容纳要组装在一个工件中的组装零件组的容器，零件设置 具有设置有用于组装部件的部件架的工作台的区域，并且按照相同类型的单元的单元按照准备工作的顺序将针对相应类型的工件设置的组件部件输入到每个组合容器， 基于工作指令信息，以及替换缓冲器，其将每个集合容器从零件设置区域返回到根据 组装生产线中的生产订单，以便输入到组装生产线。

公开(公告)号：US5699242A

公开(公告)日：1997-12-16

申请号：US413865

申请日：1995-03-29

申请人： Zenta Togawa ,  Hiroki Morio

发明人： Zenta Togawa ,  Hiroki Morio

IPC分类号： B23Q41/00 ,  B65G61/00 ,  G05B15/02 ,  G05B19/418 ,  G06Q50/00 ,  G06Q50/04 ,  G05B15/00

CPC分类号： G05B19/41865 ,  G05B2219/31019 ,  G05B2219/32046 ,  G05B2219/32059 ,  G05B2219/32062 ,  G05B2219/34069 ,  Y02P90/04 ,  Y02P90/10 ,  Y02P90/20

摘要： A control system for controlling a plurality of automatic working apparatuses for performing different types of specified operations, respectively, so as to produce different types of, but functionally the same, work units for different types of products has a first data memory, provided for each of the working apparatuses, which controls each working apparatus independently from the other so as to perform a specified operation and a second data memory sharing a common memory area of the first data memory which stores operation data indicating types of operations of the respective working apparatuses and governs the first data memories so as to transfer the operation data to the first data memories therefrom all at once, whereby causing the working apparatuses to perform the different types of specified operations so as to complete a work unit.

摘要翻译： 一种控制系统，用于分别控制用于执行不同类型的指定操作的多个自动工作装置，以便产生用于不同类型产品的不同类型但功能相同的工作单元具有为每个产品提供的第一数据存储器 对每个工作装置独立地进行控制以执行指定的操作的第一数据存储器的第二数据存储器和存储指示各个工作装置的操作类型的操作数据的第二数据存储器的第二数据存储器;以及 控制第一数据存储器，以一次将操作数据传送到第一数据存储器，从而使工作装置执行不同类型的指定操作，以便完成工作单元。