公开(公告)号：US20100258496A1

公开(公告)日：2010-10-14

申请号：US12746075

申请日：2008-12-04

申请人： Hidetoshi Hidaka ,  Takahiro Ichi

发明人： Hidetoshi Hidaka ,  Takahiro Ichi

IPC分类号： B01D63/00 ,  B01D61/24

CPC分类号： B01D71/68 ,  B01D69/02 ,  B01D69/087 ,  B01D2325/02 ,  B01D2325/04

摘要： It is intended to provide a porous hollow fiber membrane for treating blood which suffers from little mechanical damage in the course of production, transfer or handling and shows excellent fractionation properties though it is a thinned polysulfone-based hollow fiber membrane. A porous hollow fiber membrane for treating blood which comprises a polysulfone-based polymer and polyvinylpyrrolidone and has a gradient porous structure with an increase in pore size from the inside to the outside along the membrane thickness direction, characterized in that the porous structure has a membrane thickness of 25 μm or more but less than 40 μm, and fibrils having an average diameter of from 100 to 200 μm are provided in such a manner that the ratio (To/Ti) of the average outside diameter (To) along the membrane thickness direction to the average inside diameter (Ti) is adjusted to not more than 2.

摘要翻译： 旨在提供一种用于处理血液的多孔中空纤维膜，其在生产，转移或处理过程中几乎没有机械损伤，并且通过薄的聚砜基中空纤维膜表现出优异的分级性能。 一种用于处理血液的多孔中空纤维膜，其包含聚砜类聚合物和聚乙烯吡咯烷酮，并且具有沿着膜厚度方向从内向外扩大孔径的梯度多孔结构，其特征在于，所述多孔结构具有膜 厚度为25μm以上且小于40μm的平均直径为100〜200μm的原纤维，使得沿着膜厚度的平均外径（To）的比（To / Ti） 方向平均内径（Ti）调整为不大于2。

公开(公告)号：US20070007193A1

公开(公告)日：2007-01-11

申请号：US10553950

申请日：2004-04-23

申请人： Yukihiko Uchi ,  Makoto Fukuda ,  Satoshi Uezumi ,  Hidetoshi Hidaka ,  Takayasu Fujimura

发明人： Yukihiko Uchi ,  Makoto Fukuda ,  Satoshi Uezumi ,  Hidetoshi Hidaka ,  Takayasu Fujimura

IPC分类号： B01D63/02

CPC分类号： B01D63/02 ,  A61M1/16 ,  A61M2202/0498 ,  A61M2205/15 ,  B01D63/021 ,  B01D2313/14 ,  B01D2313/20

摘要： An object of the present invention is to provide a hollow fiber membrane type body fluid treatment device having very high substance removal performance which was not sufficiently achieved in a prior art and allowing the effective prevention of damage to hollow fiber membrane end portion due to impact by falling or impact by water flow. The hollow fiber membrane type body fluid treatment device comprising a hollow fiber membrane type body fluid treatment module comprising at least a tubular housing charged with a hollow fiber membrane bundle having resin layer fixed the bundle with a resin composition at both ends thereof and connection ports for a treatment liquid inlet and outlet formed in the outer peripheral surface of the tubular housing near both ends thereof and header caps provide with connection ports for a treatment target liquid fitted to both ends of the tubular housing. The hollow fiber membrane type fluid treatment device is characterized in that the device has a diameter-expanding portion allowing hollow fiber membranes to be placed so that distances between the hollow fiber membranes can be gradually increased toward the end face of the treatment liquid inlet on the inner surface of the tubular housing at the inlet side of the treatment liquid.

摘要翻译： 本发明的目的是提供一种中空纤维膜型体液处理装置，其具有非常高的物质去除性能，其在现有技术中不能充分实现，并且能够有效地防止由于冲击而导致的中空纤维膜端部的损伤 坠落或水流冲击。 中空纤维膜型体液处理装置，其具有中空纤维膜型体液处理模块，所述中空纤维膜型体液处理模块至少包括带有中空纤维膜束的管状壳体，所述中空纤维膜束的树脂层在两端固定有树脂组合物， 靠近其两端形成在管状壳体的外周表面中的处理液入口和出口以及集管盖为装配在管状壳体两端的处理目标液体提供连接口。 中空纤维膜型流体处理装置的特征在于，该装置具有直径扩大部分，其允许放置中空纤维膜，使得中空纤维膜之间的距离可以逐渐增加到处理液入口的端面上 在处理液体的入口侧的管状壳体的内表面。

公开(公告)号：US09616393B2

公开(公告)日：2017-04-11

申请号：US12746075

申请日：2008-12-04

申请人： Hidetoshi Hidaka ,  Takahiro Ichi

发明人： Hidetoshi Hidaka ,  Takahiro Ichi

IPC分类号： B01D69/08 ,  B01D71/68 ,  B01D69/02

CPC分类号： B01D71/68 ,  B01D69/02 ,  B01D69/087 ,  B01D2325/02 ,  B01D2325/04

摘要： It is intended to provide a porous hollow fiber membrane for treating blood which suffers from little mechanical damage in the course of production, transfer or handling and shows excellent fractionation properties though it is a thinned polysulfone-based hollow fiber membrane. A porous hollow fiber membrane for treating blood which comprises a polysulfone-based polymer and polyvinylpyrrolidone and has a gradient porous structure with an increase in pore size from the inside to the outside along the membrane thickness direction, characterized in that the porous structure has a membrane thickness of 25 μm or more but less than 40 μm, and fibrils having an average diameter of from 100 to 200 μm are provided in such a manner that the ratio (To/Ti) of the average outside diameter (To) along the membrane thickness direction to the average inside diameter (Ti) is adjusted to not more than 2.

公开(公告)号：US08496826B2

公开(公告)日：2013-07-30

申请号：US10553950

申请日：2004-04-23

申请人： Yukihiko Uchi ,  Makoto Fukuda ,  Satoshi Uezumi ,  Hidetoshi Hidaka ,  Takayasu Fujimura

发明人： Yukihiko Uchi ,  Makoto Fukuda ,  Satoshi Uezumi ,  Hidetoshi Hidaka ,  Takayasu Fujimura

IPC分类号： B01D63/02 ,  B01D61/24

CPC分类号： B01D63/02 ,  A61M1/16 ,  A61M2202/0498 ,  A61M2205/15 ,  B01D63/021 ,  B01D2313/14 ,  B01D2313/20

摘要： A hollow fiber membrane type fluid treatment device having at least a body portion of tubular housing containing a hollow fiber membrane bundle. In the hollow fiber membrane type fluid treatment device, an inner surface of a body portion of the tubular housing at a side of a treatment liquid inlet has a body straight portion and an end tapered portion which increases in diameter toward an end face of the housing body portion, the hollow fiber membrane is arranged so that a distance between the hollow fiber membranes is gradually increased toward the end face on the treatment liquid inlet side along a taper of a tapered portion of the inner surface of the housing body portion, and a liquid to be treated flows within the hollow fiber membranes and a treatment liquid flows outside of the hollow fiber membranes.

摘要翻译： 一种中空纤维膜型流体处理装置，其至少具有包含中空纤维膜束的管状壳体的主体部分。 在中空纤维膜型流体处理装置中，管状壳体在处理液入口侧的主体部分的内表面具有主体直线部分和朝向壳体的端面直径增大的端部锥形部分 中空纤维膜被布置成使得中空纤维膜之间的距离沿着壳体主体部分的内表面的锥形部分的锥度朝着处理液入口侧的端面逐渐增大，并且 待处理的液体在中空纤维膜内流动，处理液体流过中空纤维膜外。