-
1.发明授权Organoselenium compounds with pro-oxidant activity and pharmaceutical use thereof 失效具有促氧化活性的有机硒化合物及其药物用途
公开(公告)号：US6057310A
公开(公告)日：2000-05-02
申请号：US120436
申请日：1998-07-22
申请人： Jinzhu Xu , Georges Appere , Jean Chaudiere , Jean-Claude Yadan
发明人： Jinzhu Xu , Georges Appere , Jean Chaudiere , Jean-Claude Yadan
IPC分类号： C07D293/10 , C07D293/12 , C07J51/00 , A61K31/41 , C07D421/12
CPC分类号： C07D293/12 , C07D293/10 , C07J51/00
摘要： Compounds represented by the following formula I: ##STR1## in which: R.sup.1 to R.sup.5 can have various meanings of which alkyl, substituted or non-substituted aryl, and m is equal to 0 or 1, X is selected from (CR.sup.6 R.sup.7).sub.n in which n=0 or 1, and CO are disclosed. These compounds are useful as anti-tumor drugs, especially with pro-oxidizing activity.
摘要翻译： 由下式I表示的化合物：其中：R 1至R 5可以具有其中烷基，取代或未取代的芳基，m等于0或1的各种含义，X选自（CR 6 R 7）n，其中n = 0或1，并公开CO。 这些化合物可用作抗肿瘤药物，特别是具有促氧化活性。
-
2.发明授权Use of novel organoselenium compounds as pro-oxidizing agents their methods of preparation and pharmaceutical compositions and application thereof 失效使用新型有机硒化合物作为前体氧化剂，其制备方法和药物组合物及其应用
公开(公告)号：US6001825A
公开(公告)日：1999-12-14
申请号：US771442
申请日：1996-12-20
申请人： Jinzhu Xu , Georges Appere , Jean Chaudiere , Jean-Claude Yadan
发明人： Jinzhu Xu , Georges Appere , Jean Chaudiere , Jean-Claude Yadan
IPC分类号： C07D293/10 , C07D293/12 , C07J51/00 , A61K33/04
CPC分类号： C07D293/12 , C07D293/10 , C07J51/00
摘要： Compounds represented by the following formula I: ##STR1## in which: R.sup.1 to R.sup.5 can have various meanings of which alkyl, substituted or non-substituted aryl, and m is equal to 0 or 1, X is selected from (CR.sup.6 R.sup.7).sub.n in which n=0 or 1, and CO are disclosed. These compounds are useful as anti-tumor drugs, especially with pro-oxidizing activity.
摘要翻译： 由下式I表示的化合物：其中：R 1至R 5可以具有其中烷基，取代或未取代的芳基，m等于0或1的各种含义，X选自（CR 6 R 7）n，其中n = 0或1，并公开CO。 这些化合物可用作抗肿瘤药物，特别是具有促氧化活性。
-
3.发明授权Use of novel organoselenium compounds as pro-oxidizing agents, their methods of preparation and pharmaceutical compositions and application thereof 失效使用新型有机硒化合物作为前体氧化剂，其制备方法和药物组合物及其应用
公开(公告)号：US6130212A
公开(公告)日：2000-10-10
申请号：US329755
申请日：1999-06-10
申请人： Jinzhu Xu , Georges Appere , Jean Chaudiere , Jean-Claude Yadan
发明人： Jinzhu Xu , Georges Appere , Jean Chaudiere , Jean-Claude Yadan
IPC分类号： A61K33/04 , C07D293/10 , C07D293/12 , C07J51/00 , A61K31/58 , A61K31/395 , A61K31/41
CPC分类号： C07D293/12 , C07D293/10 , C07J51/00
摘要： Compounds represented by the following formula I: ##STR1## in which: R.sup.1 to R.sup.5 can have various meanings of which alkyl, substituted or non-substituted aryl, and m is equal to 0 or 1, X is selected from (CR.sup.6 R.sup.7).sub.n in which n=0 or 1, and CO are disclosed. These compounds are useful as anti-tumor drugs, especially with pro-oxidizing activity.
摘要翻译： 由下式I表示的化合物：其中：R 1至R 5可以具有其中烷基，取代或未取代的芳基，m等于0或1的各种含义，X选自（CR 6 R 7）n，其中n = 0或1，并公开CO。 这些化合物可用作抗肿瘤药物，特别是具有促氧化活性。
-
公开(公告)号：US06407083B1
公开(公告)日：2002-06-18
申请号：US09648784
申请日：2000-08-28
申请人： Jinzhu Xu , Georges Appere , Jean Chaudiere , Jean-Claude Yadan
发明人： Jinzhu Xu , Georges Appere , Jean Chaudiere , Jean-Claude Yadan
IPC分类号： C07D29312
CPC分类号： C07D293/12 , C07D293/10 , C07J51/00
摘要： Compounds represented by the following formula I: in which: R1 to R5 can have various meanings of which alkyl, substituted or non-substituted aryl, and m is equal to 0 or 1, X is selected from (CR6R7)n in which n=0 or 1, and CO are disclosed. These compounds are useful as anti-tumor drugs, especially with pro-oxidizing activity.
摘要翻译： 由下式I表示的化合物：其中：R 1至R 5可以具有其中烷基，取代或未取代的芳基，m等于0或1的各种含义，X选自（CR 6 R 7）n，其中n = 0或1，并公开CO。 这些化合物可用作抗肿瘤药物，特别是具有促氧化活性。
-
-
-
搜索结果
4 条记录 (耗时 0.009 秒)
