公开(公告)号：US06953581B2

公开(公告)日：2005-10-11

申请号：US09784962

申请日：2001-02-16

Applicant: Gordon Moore Allan ,  Brian Martin Meehan ,  John Albert Ellis ,  George Steven Krakowka ,  Jean-ChrJistophe Francis Audonnet

Inventor： Gordon Moore Allan ,  Brian Martin Meehan ,  John Albert Ellis ,  George Steven Krakowka ,  Jean-ChrJistophe Francis Audonnet

IPC: A61K39/395 ,  A61K39/00 ,  A61K39/295 ,  A61P31/12 ,  A61P31/22 ,  A61P37/04 ,  A61P43/00 ,  C07K14/005 ,  C07K14/01 ,  C12N7/00 ,  H61K39/295 ,  H61K39/12

CPC classification number: C07K14/005 ,  A61K39/00 ,  A61K39/12 ,  A61K2039/5252 ,  A61K2039/552 ,  A61K2039/55566 ,  A61K2039/70 ,  C12N7/00 ,  C12N2750/10022 ,  C12N2750/10034 ,  C12N2750/14322 ,  C12N2750/14334 ,  Y10S424/815 ,  Y10S435/81

Abstract: The invention relates to antigenic preparations and vaccines directed against the porcine multisystemic wasting syndrome (PMWS), comprising at least one porcine circovirus antigen, preferably type II, and at least one porcine parvovirus antigen.

Abstract translation: 本发明涉及针对猪多系统消耗综合征（PMWS）的抗原制剂和疫苗，其包含至少一种猪圆环病毒抗原，优选II型和至少一种猪细小病毒抗原。

公开(公告)号：US06217883B1

公开(公告)日：2001-04-17

申请号：US09347594

申请日：1999-07-01

Applicant: Gordon Moore Allan ,  Brian Martin Meehan ,  John Albert Ellis ,  George Steven Krakowka ,  Jean-ChrJistophe Francis Audonnet

Inventor： Gordon Moore Allan ,  Brian Martin Meehan ,  John Albert Ellis ,  George Steven Krakowka ,  Jean-ChrJistophe Francis Audonnet

IPC: A61K39295

CPC classification number: C07K14/005 ,  A61K39/00 ,  A61K39/12 ,  A61K2039/5252 ,  A61K2039/552 ,  A61K2039/55566 ,  A61K2039/70 ,  C12N7/00 ,  C12N2750/10022 ,  C12N2750/10034 ,  C12N2750/14322 ,  C12N2750/14334 ,  Y10S424/815 ,  Y10S435/81

Abstract: The invention relates to antigenic preparations and vaccines directed against the porcine multisystemic wasting syndrome (PMWS), comprising at least one porcine circovirus antigen, preferably type II, and at least one porcine parvovirus antigen.

Abstract translation: 本发明涉及针对猪多系统消耗综合征（PMWS）的抗原制剂和疫苗，其包含至少一种猪圆环病毒抗原，优选II型和至少一种猪细小病毒抗原。

公开(公告)号：US20100092512A1

公开(公告)日：2010-04-15

申请号：US12311230

申请日：2007-09-25

Applicant: John A. Ellis ,  George Steven Krakowka

Inventor： John A. Ellis ,  George Steven Krakowka

IPC: A61K39/12 ,  C12Q1/70 ,  A61P31/14

CPC classification number: A61K39/12 ,  A61K39/00 ,  A61K2039/5252 ,  A61K2039/5254 ,  A61K2039/552 ,  C12N2750/00034 ,  C12N2750/10011

Abstract: Compositions and methods for preventing and ameliorating Porcine respiratory and reproductive syndrome virus (PRRSV)-associated diseases in pigs by immunizing against Torque teno virus (TTV) are disclosed. Also described are methods of identifying compounds for the treatment and prevention of PRRSV-associated diseases.

Abstract translation: 公开了通过免疫针对扭转腱病毒（TTV）预防和改善猪呼吸和生殖综合征病毒（PRRSV） - 猪相关疾病的组合物和方法。 还描述了鉴定用于治疗和预防PRRSV相关疾病的化合物的方法。

公开(公告)号：US20100074846A1

公开(公告)日：2010-03-25

申请号：US12225145

申请日：2007-03-02

Applicant: John A. Ellis ,  George Steven Krakowka ,  Kathleen Anne McIntosh

Inventor： John A. Ellis ,  George Steven Krakowka ,  Kathleen Anne McIntosh

IPC: A61K49/00 ,  A61K39/02 ,  A61P31/04

CPC classification number: A61K39/105 ,  A61K2039/54

Abstract: Porcine models for studying bacterial gastritis and gastric and duodenal ulcer disease caused by Campylobacter pathogens, such as C. coli are described, as well as methods of identifying vaccines and compounds for treating and/or preventing Campylobacter infection using the animal models. Also described are methods of preventing Campylobacter infection in swine, such as infection caused by C. coli, using immunogenic proteins and nucleic acids derived from Campylobacter pathogens, such as C. coli.

Abstract translation: 描述了用于研究由弯曲杆菌病原体引起的细菌性胃炎和胃十二指肠溃疡疾病的猪模型，例如大肠杆菌，以及使用动物模型鉴定用于治疗和/或预防弯曲杆菌感染的疫苗和化合物的方法。 还描述了使用免疫原性蛋白质和源自弯曲杆菌病原体的核酸如大肠杆菌来预防猪中弯曲杆菌感染的方法，例如由大肠杆菌引起的感染。