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公开(公告)号:US6107087A
公开(公告)日:2000-08-22
申请号:US930589
申请日:1998-09-28
申请人: Gary P. O'Neill , Joseph A. Mancini
发明人: Gary P. O'Neill , Joseph A. Mancini
CPC分类号: C12N9/0083 , C12Q1/26 , C12Y114/99001 , C07K2319/00
摘要: The invention discloses a cDNA consisting of human cyclooxygenase-2 cDNA attached to 3'flanking sequence of human cyclooxygenase-1 methods for increasing the expression of human cyclooxygenase-2 in transformed cell and assays for preferentially and independently measuring cyclogense-2 in samples.
摘要翻译: PCT No.PCT / CA94 / 00501 Sec。 371日期:1998年9月28日 102(e)1998年9月28日PCT PCT 1994年9月13日PCT公布。 公开号WO95 / 09238 日期1995年4月6日本发明公开了一种由人环氧合酶-2 cDNA连接的cDNA,其与人环加氧酶-1的3'侧翼序列连接,用于增加人环氧合酶-2在转化细胞中的表达,并优选并独立测定环状加氧酶-2 2样品。
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公开(公告)号:US06689596B2
公开(公告)日:2004-02-10
申请号:US10027961
申请日:2001-10-25
申请人: Gary P. O'Neill , Joseph A. Mancini
发明人: Gary P. O'Neill , Joseph A. Mancini
IPC分类号: C12N902
CPC分类号: C12N9/0083 , C07K2319/00 , C12Q1/26 , C12Y114/99001 , G01N33/5005
摘要: The invention discloses a cDNA consisting of human cyclooxygenase-2 cDNA attached to 3′ flanking sequence of human cyclooxygenase-1 methods for increasing the expression of human cyclooxygenase-2 in transformed cells and assays for preferentially and independently measuring cyclogenase-2 in samples.
摘要翻译: 本发明公开了一种由人环加氧酶-2 cDNA连接的cDNA,该环加氧酶-2连接于人环氧合酶-1的3'侧翼序列,用于增加转化细胞中人环氧合酶-2的表达,并且用于优先和独立地测量样品中的环化酶-2的测定。
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公开(公告)号:US06362327B1
公开(公告)日:2002-03-26
申请号:US09599781
申请日:2000-06-21
申请人: Gary P. O'Neill , Joseph A. Mancini
发明人: Gary P. O'Neill , Joseph A. Mancini
IPC分类号: C07H2104
CPC分类号: C12N9/0083 , C07K2319/00 , C12Q1/26 , C12Y114/99001 , G01N33/5005
摘要: The invention discloses a cDNA consisting of human cyclooxygenase-2 cDNA attached to 3′ flanking sequence of human cyclooxygenase-1 methods for increasing the expression of human cyclooxygenase-2 in transformed cells and assays for preferentially and independently measuring cyclogenase-2 in samples.
摘要翻译: 本发明公开了一种由人环加氧酶-2 cDNA连接的cDNA,该环加氧酶-2连接于人环氧合酶-1的3'侧翼序列,用于增加转化细胞中人环氧合酶-2的表达,并且用于优先和独立地测量样品中的环化酶-2的测定。
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