-
1.发明申请公开(公告)号：US20130071428A1
公开(公告)日：2013-03-21
申请号：US13635384
申请日：2011-03-15
CPC classification number: C07K17/02 , A61K39/00 , A61K39/385 , A61K39/40 , A61K2039/6037 , A61K2039/627 , C07K7/08 , C07K14/33 , C07K16/1282 , A61K2300/00
Abstract: The present invention relates to conjugates comprising a peptide of at least 10 amino acid residues comprising the amino acid sequence GITELKKL for induction of potent humoral and cellular immune responses when administered to subjects having antibodies against tetanus toxoid. In one embodiment the invention relates to a prophylactic and therapeutic vaccine and in a further embodiment the invention relates to the treatment or prevention of cancer or an infectious disease.
Abstract translation: 本发明涉及包含至少10个氨基酸残基的肽的缀合物，其包含氨基酸序列GITELKKL，用于在施用于具有抗破伤风类毒素抗体的受试者时诱导有效的体液和细胞免疫应答。 在一个实施方案中，本发明涉及预防和治疗性疫苗，并且在进一步的实施方案中，本发明涉及癌症或感染性疾病的治疗或预防。
-
2.发明授权公开(公告)号：US09522962B2
公开(公告)日：2016-12-20
申请号：US13635384
申请日：2011-03-15
CPC classification number: C07K17/02 , A61K39/00 , A61K39/385 , A61K39/40 , A61K2039/6037 , A61K2039/627 , C07K7/08 , C07K14/33 , C07K16/1282 , A61K2300/00
Abstract: The present invention relates to conjugates comprising a peptide of at least 10 amino acid residues comprising the amino acid sequence GITELKKL (residues 383-390 of SEQ ID NO: 3) for induction of potent humoral and cellular immune responses when administered to subjects having antibodies against tetanus toxoid. In one embodiment the invention relates to a prophylactic and therapeutic vaccine and in a further embodiment the invention relates to the treatment or prevention of cancer or an infectious disease.
Abstract translation: 本发明涉及包含至少10个氨基酸残基的肽的缀合物，其包含氨基酸序列GITELKKL（SEQ ID NO：3的残基383-390），用于在施用于具有抗体的抗体的受试者时诱导有效的体液和细胞免疫应答 破伤风类毒素。 在一个实施方案中，本发明涉及预防和治疗性疫苗，并且在进一步的实施方案中，本发明涉及癌症或感染性疾病的治疗或预防。
-
Search Results
2
records
(took 0.01 seconds)
