公开(公告)号：US20250102786A1

公开(公告)日：2025-03-27

申请号：US18817025

申请日：2024-08-27

Applicant: POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION ,  THE ASAN FOUNDATION ,  FOUNDATION FOR INDUSTRY COOPERATION UNIVERSITY OF ULSAN

Inventor： Ki Hean KIM ,  Won Yeong PARK ,  Su Il JEON ,  Seung-Mo HONG ,  Jinho SHIN

IPC: G02B21/00 ,  G01N21/64 ,  G02B21/08

Abstract: Disclosed are an open-top two-photon light sheet microscope and an operating method thereof. The open-top two-photon light sheet microscope is capable of obtaining high-depth imaging, high-contrast resolution, and double contrast based on a Bessel beam, and enables rapid three-dimensional imaging by continuously capturing tissue on a per-plane basis without an optical clearing process or a sectioning process, and an operating method thereof.