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公开(公告)号:US20140255518A1
公开(公告)日:2014-09-11
申请号:US14114727
申请日:2012-04-27
申请人: Peng Li , Scott A. Waldman , Evan Wuthrick
发明人: Peng Li , Scott A. Waldman , Evan Wuthrick
IPC分类号: C07K14/58 , C07K14/575 , A61K45/06 , A61K38/22
CPC分类号: C07K14/58 , A61K38/10 , A61K38/16 , A61K38/22 , A61K38/2242 , A61K45/06 , C07K14/575
摘要: Compositions comprising a guanylyl cyclase C agonist in an amount effective to protect intestinal tissue against radiation or chemotherapy and methods of using such compositions to prevent GI syndrome in cancer patient undergoing radiation or chemotherapy and in individuals exposed to or susceptible to exposure to radiation are disclosed.
摘要翻译: 公开了包含有效保护肠组织免受辐射或化学疗法的量的鸟苷酸环化酶C激动剂的组合物和使用这些组合物来预防接受放射或化疗的癌症患者中的GI综合征以及暴露于或易于暴露于辐射的个体中的GI综合征的方法。