公开(公告)号：US20190080052A1

公开(公告)日：2019-03-14

申请号：US16051444

申请日：2018-07-31

Applicant: Gregory Edward Lewis ,  Charles Geiger

Inventor： Gregory Edward Lewis ,  Charles Geiger

IPC: G06F19/26 ,  G01J3/46 ,  G06F19/24 ,  G06T7/00 ,  G06T7/90 ,  G06T11/00

Abstract: A perpetual bioinformatics and virtual colorimeter expert system platform is disclosed to remotely measure dermal and epidermal properties with precision and to enhance decision-making. Some embodiments of the system provide for virtual tristimulus colorimetry, wherein a capture device captures one or more dermal images of one or more skin area of a user. A color grid includes one or more permutations of a plurality of recorded predetermined colors. A scale of the color grid is recorded as being printed or projected at a predetermined size. Application of the virtual tristimulus colorimeter to one of the images is performed. As a result of this application the image is calibrated according to the virtual tristimulus colorimeter. In some embodiments the capture device may include a smartphone camera, interactive with the virtual tristimulus colorimeter smartphone application.

公开(公告)号：US08923475B2

公开(公告)日：2014-12-30

申请号：US13363307

申请日：2012-01-31

Applicant: Marcus Gutfleisch ,  Thomas Tücking ,  Douglas Howard ,  Edward Lewis Calderon

Inventor： Marcus Gutfleisch ,  Thomas Tücking ,  Douglas Howard ,  Edward Lewis Calderon

IPC: G01N23/04 ,  A61B6/03 ,  A61B6/00

CPC classification number: G01N23/046 ,  A61B6/032 ,  A61B6/4085 ,  A61B6/4476 ,  A61B6/54 ,  G01N2223/306 ,  G01N2223/3303 ,  G01N2223/419

Abstract: A system for motion control of a cone-beam tomography recording device includes a drive system configured to position a paired radiation source and radiation detector relative to an object. The system further includes a controller configured to: initiate a trigger plan operable as a function of a constant frequency control signal, activate the paired radiation source and radiation detector in accordance with the trigger plan, drive, in response to the trigger plan, the first drive system to a steady operating state derived as a function of the constant frequency, capture a plurality of broadcast radiation signals representative of a plurality of two dimensional images of the object such that the two dimensional images are defined equidistant positions defined by the trigger plan and as a function of the constant frequency signal, and generate a three dimensional representation of the object based on the plurality of two dimensional images.

Abstract translation: 锥束断层摄影记录装置的运动控制系统包括配置成相对于物体定位成对的辐射源和辐射检测器的驱动系统。 该系统还包括控制器，该控制器被配置为：启动可作为恒定频率控制信号的函数操作的触发计划，根据触发计划，根据触发计划激活成对的辐射源和辐射检测器，第一 驱动系统作为恒定频率的函数导出的稳定操作状态，捕获表示对象的多个二维图像的多个广播辐射信号，使得二维图像被定义为由触发计划定义的等距位置，以及 作为恒定频率信号的函数，并且基于多个二维图像生成对象的三维表示。

公开(公告)号：US20090130019A1

公开(公告)日：2009-05-21

申请号：US11986423

申请日：2007-11-21

Applicant: Edward Lewis Tobinick

Inventor： Edward Lewis Tobinick

IPC: A61K51/00 ,  A61P43/00

CPC classification number: A61K51/1051 ,  A61K51/1018 ,  A61K51/1021

Abstract: This application concerns novel methods which enable or improve the ability of molecules, particularly large molecules, to cross the blood-brain barrier, the blood-eye barrier, and/or the blood-nerve barrier and therefore be of improved diagnostic and/or therapeutic use in humans and other mammals. These methods involve perispinal administration of imaging agents without direct intrathecal injection. Perispinal administration is defined as administration of the molecule into the anatomic area within 10 cm of the spine. Perispinal administration results in absorption of the imaging agent into the vertebral venous system. The vertebral venous system is capable of transporting molecules into the brain, the eye, the retina, the auditory apparatus, the cranial nerves, the head, the spine, the spinal cord, the vertebral bodies, the dorsal root ganglia, and the nerve roots via retrograde venous flow, thereby bypassing the blood-brain barrier and similar barriers and delivering the molecules to the brain, the eye, the retina, the auditory apparatus, the cranial nerves, the head, the spine (including the vertebral bodies), the spinal cord, the dorsal root ganglia, or the nerve roots. This method may be utilized for a wide variety of diagnostic agents, including, but not limited to biologics, monoclonal antibodies, fusion proteins, monoclonal antibody fragments, antibodies to tumor antigens, hormones, cytokines, anti-cytokines, interleukins, anti-interleukins, interferons, colony-stimulating factors, cancer chemotherapeutic agents, growth factors, anti-virals and antibiotics, including those which are radiolabeled, iodinated, or otherwise altered to facilitate diagnostic imaging. Included in these novel methods are perispinal delivery of amyloid imaging agents, and other ligands radiolabeled with [11C] or [18F] to faciliate PET imaging of the brain.

公开(公告)号：US07526544B2

公开(公告)日：2009-04-28

申请号：US10116951

申请日：2002-04-05

Applicant: Edward Lewis Hauck ,  Noel Simen Otterness

Inventor： Edward Lewis Hauck ,  Noel Simen Otterness

IPC: G06F15/173

CPC classification number: G06F11/2097 ,  G06F11/2071 ,  G06F11/2089 ,  H04L29/06 ,  H04L67/1002 ,  H04L2029/06054

Abstract: A message tracker having a transfer monitor, a set of registers, and at least one arithmetic unit increases performance and reliability when transmitting or receiving messages within a computer system. A set of message parameters such as a current address, a remaining length, and a communicated length are stored within the set of registers. The transfer monitor observes data transfers on a multi-tenant bus in order to detect data transfers related to the message and provide an update signal. The message parameters within the registers are updated in response to the update signal. The process of detecting and updating is repeated until the entire message is transferred, and the message tracker then informs a control processor or process that communication of the message has occurred. To facilitate message coalescing, several message trackers may share a message queue that is configured to store message parameters corresponding to completed messages.

Abstract translation: 具有传送监视器，一组寄存器和至少一个算术单元的消息跟踪器在计算机系统内发送或接收消息时增加了性能和可靠性。 一组消息参数（如当前地址，剩余长度和通信长度）存储在寄存器组内。 传输监视器观察多租户总线上的数据传输，以便检测与消息相关的数据传输并提供更新信号。 响应于更新信号更新寄存器内的消息参数。 重复检测和更新的过程，直到整个消息被传送，并且消息跟踪器然后通知控制处理器或处理已经发生消息的通信。 为了便于消息合并，几个消息跟踪器可以共享被配置为存储对应于已完成消息的消息参数的消息队列。

公开(公告)号：US07242742B2

公开(公告)日：2007-07-10

申请号：US11187128

申请日：2005-07-21

Applicant: Edward Lewis Calderon ,  Francisco M. Hernandez-Guerra ,  Ali Bani-Hashemi ,  Farhad A. Ghelmansarai

Inventor： Edward Lewis Calderon ,  Francisco M. Hernandez-Guerra ,  Ali Bani-Hashemi ,  Farhad A. Ghelmansarai

IPC: A61N5/10 ,  A61B5/05

CPC classification number: A61N5/1049 ,  A61N2005/1054 ,  G21K5/04 ,  H05G2/00

Abstract: Some embodiments include a particle source, an RF power source, an accelerator waveguide, and an imaging device. The particle source is to generate a first injector current and a second injector current, the first injector current being less than the second injector current. The RF power source is to generate first RF power at a first pulse rate and second RF power at a second pulse rate, the first pulse rate being greater than the second pulse rate. The accelerator waveguide is to accelerate a first electron beam based on the first injector current and the first RF power and to accelerate a second electron beam based on the second injector current and the second RF power, and the imaging device is to acquire an image based on the first electron beam. The second electron beam may be used to deliver treatment radiation to a patient.

公开(公告)号：US06874420B2

公开(公告)日：2005-04-05

申请号：US10626915

申请日：2003-07-25

Applicant: Clarence A. Lewis, Jr. ,  Richard Dale Lewis ,  James Edward Lewis

Inventor： Clarence A. Lewis, Jr. ,  Richard Dale Lewis ,  James Edward Lewis

IPC: B41F33/00 ,  B41F1/54

CPC classification number: B41F33/0081 ,  B41P2233/52 ,  Y10S101/46

Abstract: A system, method, and process that determine and automatically correct registration errors between printed objects and mechanically produced objects using advanced image processing techniques is disclosed. Means are also presented for maintaining all registered functions to within very close tolerances during normal running, with other means for rapidly obtaining initial registration with substantial savings in material waste. The disclosed system and method/process are compatible with the printing and converting industry in which rolls of material are processed by printing a number of colors that require close registration especially in pictorial representation. These roll-fed printing machines are quite versatile and in addition to the printing of any number of colors on both front and back can perform any number of additional operations on the printed web at the same time. Some of these additional operations can be the punching of line holes, scoring, perforation and die cutting all of which impart a specific shape mechanically on the printed web. All of these functions must be initially registered to each other and maintained within close tolerances during normal running conditions. The presently disclosed registration system permits these initial registration procedures to be performed with high accuracy, speed, and across a wide variety of web materials and colors. The system generally applies to any web material (5701) on which register marks (5702) are applied, wherein images of the web are obtained (5703) and image processed (5704) under optional control of an operator interface display (5705), resulting in web press motor control (5706) to affect improved print registration on the web material (5701).

Abstract translation: 公开了一种使用先进的图像处理技术来确定和自动校正印刷对象与机械制作对象之间的注册错误的系统，方法和过程。 还提供了在正常运行期间将所有注册功能保持在非常接近的公差内的手段，其他手段用于快速获得初始注册，同时大量节省材料浪费。 所公开的系统和方法/过程与印刷和转换行业兼容，其中通过打印需要紧密注册的多种颜色，特别是在图形表示中来处理材料卷。 这些卷筒印刷机是非常通用的，除了在前面和后面打印任何数量的颜色，可以同时在印刷的卷筒纸上执行任何数量的附加操作。 这些附加操作中的一些可以是冲孔线孔，打孔，穿孔和模切，所有这些都将机械地赋予印刷网上的特定形状。 所有这些功能必须首先相互注册，并在正常运行条件下保持在公差范围内。 目前公开的注册系统允许这些初始注册过程以高精度，高速度和跨越多种网络材料和颜色来执行。 该系统通常适用于在其上应用了注册标记（5702）的任何网络材料（5701），其中在操作员界面显示（5705）的可选控制下获得网络的图像（5703）和图像处理（5704），从而得到 在网印机电机控制（5706）中，影响网页材料上改进的打印注册（5701）。

公开(公告)号：US6052435A

公开(公告)日：2000-04-18

申请号：US7441

申请日：1998-01-15

Applicant: Francisco M. Hernandez-Guerra ,  Edward Lewis Calderon ,  Simon John Forknall ,  David L. Pond

Inventor： Francisco M. Hernandez-Guerra ,  Edward Lewis Calderon ,  Simon John Forknall ,  David L. Pond

IPC: A61N5/10 ,  G21F5/04

CPC classification number: A61N5/1042

Abstract: A system and method for radiation therapy delivery. Prior to the delivery of the actual treatment, a run up is executed in order to stabilize the RF system. The run up is accomplished by initiating the triggers with the injector and RF pulses out of phase so that the electrons, for example, in the accelerating waveguide do not get accelerated even though the RF system is being pulsed. The RF warm up period during which the injector and RF pulses are out of phase, ends at RAD ON (Radiation On) with the injector pulse being phase-shifted to coincide in time with the RF pulse thereby resulting in the production of electron beam pulses. Following the application of this run up period, precise and rapid disabling and enabling of the treatment beam between IMRT fields can be accomplished. The electron injection is phase-shifted in and out without affecting either the injector or the RF pulse amplitudes, thereby allowing transitions between a stable RAD ON beam and no beam between one pulse and the next.

Abstract translation: 放射治疗递送的系统和方法。 在实际处理之前，为了稳定射频系统，执行一个运行。 通过启动具有喷射器和RF脉冲异相的触发来实现运行，使得例如在加速波导中的电子即使RF系统被脉冲也不会加速。 注射器和RF脉冲异相的RF预热期间以RAD ON（辐射开）结束，喷射器脉冲被相移以在时间上与RF脉冲一致，从而产生电子束脉冲 。 随着这个运行时间的应用，可以实现IMRT领域之间的治疗束的精确和快速的禁用和使能。 电子注入是相互移入和移出的，而不影响注射器或RF脉冲幅度，从而允许稳定的RAD ON波束与一个脉冲与下一个脉冲之间的波束之间的转换。

公开(公告)号：US2336487A

公开(公告)日：1943-12-14

申请号：US42728042

申请日：1942-01-19

Applicant: EDWARD LEWIS ,  MICHELBRINK HENRY A

Inventor： EDWARD LEWIS ,  MICHELBRINK HENRY A

IPC: E21C25/62

CPC classification number: E21C25/62

公开(公告)号：US1408367A

公开(公告)日：1922-02-28

申请号：US46949121

申请日：1921-05-14

Applicant: EDWARD LEWIS GEORGE

Inventor： EDWARD LEWIS GEORGE

IPC: B65D6/08

CPC classification number: B65D9/36

公开(公告)号：US1047437A

公开(公告)日：1912-12-17

申请号：US1911632431

申请日：1911-06-10

Applicant: OGDEN JOHN EDWARD LEWIS

Inventor： OGDEN JOHN EDWARD LEWIS

CPC classification number: F16T1/14 ,  B67D7/38 ,  Y10T137/3024 ,  Y10T137/3059 ,  Y10T137/3105 ,  Y10T137/7303