公开(公告)号：US09708243B2

公开(公告)日：2017-07-18

申请号：US14383182

申请日：2012-03-07

申请人： Chinmoy Nandi ,  Narendra Gangal ,  Pramod Purohit ,  Vinay Ketkar ,  Dilip Kashelikar

发明人： Chinmoy Nandi ,  Narendra Gangal ,  Pramod Purohit ,  Vinay Ketkar ,  Dilip Kashelikar

IPC分类号： C07C209/68 ,  C07C209/02 ,  C07C209/36

CPC分类号： C07C209/68 ,  C07C209/02 ,  C07C209/36 ,  C07C211/56 ,  C07C211/54

摘要： A process for preparing 4-aminodiphenylamine (4-ADPA) comprising steps of coupling of aniline with nitrobenzene in presence of a suitable base, e.g. tetramethylammonium hydroxide (TMAH), hydrogenation of the coupling mass, phase separation, hydrogenation of azobenzene in the separated organic mass and fractional distillation for 4-ADPA recovery. An improvement in 4-ADPA recovery and a lowering of tar formation are obtained due to azobenzene reduction prior to 4-ADPA isolation. Also a gain in volume productivity of 4-ADPA is obtained by suitably altering the batch cycle time of the coupling reaction.

公开(公告)号：US20150045584A1

公开(公告)日：2015-02-12

申请号：US14383182

申请日：2012-03-07

申请人： Chinmoy Nandi ,  Narendra Gangal ,  Pramod Purohit ,  Vinay Ketkar ,  Dilip Kashelikar

发明人： Chinmoy Nandi ,  Narendra Gangal ,  Pramod Purohit ,  Vinay Ketkar ,  Dilip Kashelikar

IPC分类号： C07C209/68

CPC分类号： C07C209/68 ,  C07C209/02 ,  C07C209/36 ,  C07C211/56 ,  C07C211/54

摘要： A process for preparing 4-aminodiphenylamine (4-ADPA) comprising steps of coupling of aniline with nitrobenzene in presence of a suitable base, e.g. tetramethylammonium hydroxide (TMAH), hydrogenation of the coupling mass, phase separation, hydrogenation of azobenzene in the separated organic mass and fractional distillation for 4-ADPA recovery. An improvement in 4-ADPA recovery and a lowering of tar formation are obtained due to azobenzene reduction prior to 4-ADPA isolation. Also a gain in volume productivity of 4-ADPA is obtained by suitably altering the batch cycle time of the coupling reaction.

摘要翻译： 一种制备4-氨基二苯胺（4-ADPA）的方法，包括以下步骤：在合适的碱存在下，将苯胺与硝基苯偶联。 四甲基氢氧化铵（TMAH），偶联剂的氢化，相分离，偶氮苯在分离的有机物中的氢化和4-ADPA回收的分馏。 由于在4-ADPA分离之前的偶氮苯还​​原，获得4-ADPA回收率的改善和焦油形成的降低。 通过适当地改变偶联反应的批次循环时间，也可以获得4-ADPA的体积生产率的增加。