公开(公告)号：US20100189856A1

公开(公告)日：2010-07-29

申请号：US12648139

申请日：2009-12-28

申请人： Elizabeth Tranquil (Tikhomirova) ,  Zosya Albertovna Kanarskaya ,  Dennis Tranquil (Dmitry Tikhomirov) ,  Albert Vladimirovich Kanarsky

发明人： Elizabeth Tranquil (Tikhomirova) ,  Zosya Albertovna Kanarskaya ,  Dennis Tranquil (Dmitry Tikhomirov) ,  Albert Vladimirovich Kanarsky

IPC分类号： A23K1/00 ,  B01J20/22

CPC分类号： B01J20/24 ,  A23K10/14 ,  A23K10/18 ,  A23K10/37 ,  A23K10/38 ,  A23K20/10 ,  A23K20/163 ,  B01J20/22 ,  B01J2220/44 ,  B01J2220/4825 ,  B01J2220/4831 ,  B01J2220/4868 ,  Y02P60/873 ,  Y02P60/877

摘要： Mycotoxins prevailing in Northern climates have been until now proven difficult to deactivate in animal feed by binding, in contrast to mycotoxins prevailing in the Southern climates. Meanwhile, both types of toxins present a considerable risk factor for agricultural animal health and performance. A method of adsorbing and rendering harmless for animals an expanded range of both Northern and Southern mycotoxins found in contaminated feed is proposed. According to the invention, a combination of modified plant ligno-polysaccharide material and traditional mycotoxin binding components is added to the feed of agricultural and companion animals in an amount sufficient to abate the negative effects of both types of mycotoxins present.

摘要翻译： 现在在北方气候中存在的真菌毒素直到现在证明在动物饲料中通过结合难以失活，与南方气候中盛行的真菌毒素相反。 同时，两种类型的毒素对于农业动物健康和表现都具有相当大的危险因素。 提出了一种吸附和使动物无害化的方法，在污染饲料中发现的北部和南部霉菌毒素的扩大范围。 根据本发明，将修饰植物木素多糖材料和传统霉菌毒素结合成分的组合以足以减轻存在的两种类型霉菌毒素的负面影响的量加入农业和伴侣动物的饲料中。

公开(公告)号：US20120070516A1

公开(公告)日：2012-03-22

申请号：US13233021

申请日：2011-09-15

申请人： Dennis Tranquil ,  Albert Vladimirovich Kanarsky ,  Elizabeth Tranquil ,  Zosya Albertovna Kanarskaya ,  Arthur Tigranovich Kopylov

发明人： Dennis Tranquil ,  Albert Vladimirovich Kanarsky ,  Elizabeth Tranquil ,  Zosya Albertovna Kanarskaya ,  Arthur Tigranovich Kopylov

IPC分类号： A01N65/34 ,  A01N65/44 ,  A01P1/00 ,  A01N65/06 ,  A01N65/00 ,  A01N65/12 ,  A01N65/08

CPC分类号： A23K10/14 ,  A23K10/32 ,  A23K10/37 ,  A23K10/38 ,  A23K20/10 ,  A23K20/163 ,  Y02P60/873 ,  Y02P60/877

摘要： Method is proposed useful to render harmless mycotoxins that contaminate food, animal feed and assist infection of plant hosts by microbial parasites, comprising binding mycotoxins by a novel adsorbent, consisting partially or in full of plant lignocellulosic biomass or isolated biomass components, e.g., acid hydrolysis lignin, enzymatic hydrolysis lignin, coniferous and deciduous wood, bark and needle particles, rice hulls, used coffee grounds, apricot stone shells, almond, walnut, sunflower hulls, cocoa and peanut shells. The materials may be further improved through genetic modification of plants and physicochemical treatment of lignocellulosic biomass, such as micronization. The resulting adsorbent can bind wide range of mycotoxins, including, mycotoxins difficult to bind (Ochratoxin, T-2, Deoxynivalenol, Nivalenol). Ability of porous materials containing lignin to thermally collapse at melting can be used to irreversibly entrap mycotoxins by adsorbing them in a wet system and then closing lignin pore structure under high-temperature treatment, such as drying.

摘要翻译： 提出了一种方法，用于使无害的真菌毒素污染食物，动物饲料和辅助微生物寄生虫感染植物宿主，其包括通过部分或全部植物木质纤维素生物质或分离的生物量组分（例如酸水解）的新型吸附剂结合真菌毒素 木质素，酶水解木质素，针叶和落叶木，树皮和针状颗粒，稻壳，二手咖啡渣，杏仁石，杏仁，核桃，向日葵壳，可可和花生壳。 可以通过植物的遗传修饰和木质纤维素生物质的物理化学处理如微粉化来进一步改善材料。 所得到的吸附剂可以结合多种真菌毒素，包括难以结合的真菌毒素（赭曲霉毒素，T-2，脱氧雪腐镰刀菌烯醇，新戊烯醇）。 含有木质素的多孔材料在熔融时热崩解的能力可用于不可逆地将霉菌毒素吸附在湿体系中，然后在高温处理如干燥时封闭木质素孔结构。

公开(公告)号：US20120027747A1

公开(公告)日：2012-02-02

申请号：US12899464

申请日：2010-10-06

申请人： Dennis Tranquil ,  Albert Vladimirovich Kanarsky ,  Elizabeth Tranquil ,  Zosya Albertovna Kanarskaya ,  Oleg Nickolaevich Okunev

发明人： Dennis Tranquil ,  Albert Vladimirovich Kanarsky ,  Elizabeth Tranquil ,  Zosya Albertovna Kanarskaya ,  Oleg Nickolaevich Okunev

IPC分类号： A61K36/06

CPC分类号： A61K36/06

摘要： A method of rendering harmless mycotoxins contaminating food, animal feed and assisting infection of plant hosts by microbial parasites is proposed. The method comprises binding mycotoxins by a novel adsorbent, consisting partially or in full of the biomass of filamentous fungi or isolated fungal biomass components, such as chitin, chitozan and hyrdophobins, or fungal biomass enriched in its capacity to bind said mycotoxins using fungal species and strain selection, genetic engineering of fungi, modification of fungal fermentation conditions and downstream physical and chemical treatment of fungal biomass, such as milling or micronization in a dry state. The resulting adsorbent can bind a wide range of mycotoxins, including the ones difficult to bind (Ochratoxin, T-2, DON, NIV) using a current generation of mycotoxin adsorbents based on clay, resins, yeast and bacterial biomass. The adsorbent can be used as an animal feed additive, functional food additive and agricultural fungistatic/fungicide.

摘要翻译： 提出了一种通过微生物寄生虫使无害的霉菌毒素污染食物，动物饲料和辅助植物宿主感染的方法。 该方法包括通过新颖的吸附剂结合真菌毒素，部分或完全由丝状真菌或分离的真菌生物量组分的生物质组成，例如几丁质，辣椒碱和海藻多糖，或富含其使用真菌物质结合所述真菌毒素的能力的真菌生物质， 菌株选择，真菌的基因工程，真菌发酵条件的修饰和真菌生物质的下游物理和化学处理，例如在干燥状态下的研磨或微粉化。 所得到的吸附剂可以使用当前一代基于粘土，树脂，酵母和细菌生物质的真菌毒素吸附剂，结合各种真菌毒素，包括难以结合的霉菌毒素（赭曲霉毒素，T-2，DON，NIV）。 吸附剂可用作动物饲料添加剂，功能性食品添加剂和农业抑菌/杀真菌剂。