System for treating unwanted tissue using heat and heat activated drugs

    公开(公告)号:US10980737B1

    公开(公告)日:2021-04-20

    申请号:US15452712

    申请日:2017-03-07

    Abstract: The invention can selectively heat a diseased area in the lung while minimizing heating to the healthy area and surrounding tissue. This is done by exposing the lung to an electromagnetic field causing dielectric or eddy current heating. The invention is particularly useful for treating emphysema as the diseased areas have reduced blood flow. The diseased area will heat up rapidly while the healthy tissue will be cooled by the blood flow. This is particularly effective for treating emphysema because of the low mass of the lungs and the high blood flow. To avoid heating of surrounding organs the direction of the electromagnetic energy is switched in a way it always passes through lungs but only intermittently passes through adjacent organs. If heat activated drugs are present in the lungs, they are selectively released in the heated tissue.

    Apparatus and method for forming self-retaining sutures
    4.
    发明授权
    Apparatus and method for forming self-retaining sutures 有权
    用于形成自固定缝线的装置和方法

    公开(公告)号:US08615856B1

    公开(公告)日:2013-12-31

    申请号:US12363582

    申请日:2009-01-30

    Applicant: Daniel Gelbart

    Inventor: Daniel Gelbart

    Abstract: An apparatus and method for forming retainers on a continuous strand such as, for example, of suture material and a suture produced by the same. The apparatus may include a retainer forming member configured to rotate about a first axis. The retainer forming member may include a cutter, the cutting edge of which may directed substantially inward toward, or outward away from, the first axis to define a retainer forming zone when the retainer forming member rotates about the first axis. The apparatus may further include a support member arranged adjacent to the retainer forming member and configured to receive and support the continuous strand in the retainer forming zone. When the retainer forming member rotates about the first axis, the passing strand may be intermittently or continuously cut by the cutting edge of the cutter.

    Abstract translation: 一种用于在连续股线上形成保持器的装置和方法,例如缝合材料和由其制成的缝合线。 该装置可以包括构造成围绕第一轴线旋转的保持器形成构件。 保持器形成构件可以包括切割器,其切割边缘可以朝着第一轴线或向外远离第一轴线指向,以在保持器形成构件围绕第一轴线旋转时限定保持器成形区域。 该装置还可以包括邻近保持器形成构件设置并构造成在保持器成形区域中接收和支撑连续线材的支撑构件。 当保持器形成构件围绕第一轴线旋转时,通过的线可以由切割器的切割边缘间歇地或连续地切割。

    Mixing syringe
    5.
    发明申请
    Mixing syringe 有权
    混合注射器

    公开(公告)号:US20130226148A1

    公开(公告)日:2013-08-29

    申请号:US13385627

    申请日:2012-02-28

    Abstract: A movable mixing disc is inserted into a regular syringe. The mixing disc has a small hole covered by a fine screen, allowing only saline solution to get behind the disc. When the plunger of the syringe is pressed, the saline solution emerges from the mixing disc hole as a high velocity jet, stirring up the settled particles. As the ejection continues, the mixing disc is pushed forward by the plunger in order to eliminate any unused volume.

    Abstract translation: 将可动混合盘插入常规注射器中。 混合盘具有被细筛网覆盖的小孔,只允许盐水溶液到达盘后。 当注射器的柱塞被按压时,盐溶液作为高速喷射从混合盘孔中排出,搅拌沉降的颗粒。 当喷射继续时,混合盘被柱塞向前推动,以消除任何未使用的体积。

    X-Ray radiation reduction system
    7.
    发明申请
    X-Ray radiation reduction system 审中-公开
    X射线辐射降低系统

    公开(公告)号:US20120215095A1

    公开(公告)日:2012-08-23

    申请号:US13385402

    申请日:2012-02-21

    Abstract: By exposing the ROI at full exposure and full frame rate while exposing the area outside the ROI with low exposure and up to full frame rate an overall reduction in X-Ray radiation is achieved. The resultant image has slightly lower resolution outside the ROI but better resolution (as compared to standard fluoroscopy practices) in the ROI because of reduced scattering. Different exposures are supplied to different parts of the image by using a fast shutter in conjunction with the exposure control.

    Abstract translation: 通过在全曝光和全帧速率下曝光ROI,同时以低曝光和高达全帧速率曝光ROI外部的区域,实现了X射线辐射的全面减少。 所得到的图像在ROI之外具有略低的分辨率,但是由于散射减少,ROI中的分辨率(与标准荧光透视实践相比)更好。 通过使用快门与曝光控制相结合,将不同的曝光提供给图像的不同部分。

    System for reduction of exposure to X-ray radiation
    8.
    发明授权
    System for reduction of exposure to X-ray radiation 有权
    用于减少暴露于X射线辐射的系统

    公开(公告)号:US07983391B2

    公开(公告)日:2011-07-19

    申请号:US12386895

    申请日:2009-04-27

    Abstract: To reduce X-ray exposure, an area of interest is selected in the image. The image of the selected area is updated frequently, comparable to rate of updates used today for the whole image. The rest of the image is updated at a significantly lower rate. Since the area of interest normally is a small part of the overall area, the total exposure is reduced significantly. A movable X-ray shield placed near the X-ray source blocks the radiation from areas outside the area of interest. The shield automatically retracts when the complete image is updated. The area of interest can be selected by the user or automatically selected based on activity in the image.

    Abstract translation: 为了减少X射线曝光,图像中选择感兴趣区域。 所选区域的图像经常更新,与整个图像当前使用的更新速率相当。 图像的其余部分以显着较低的速率更新。 由于感兴趣的区域通常是整个区域的一小部分,因此总体暴露量显着降低。 放置在X射线源附近的可移动的X射线屏蔽物阻挡来自感兴趣区域外的区域的辐射。 完整的图像更新后,屏幕会自动缩回。 感兴趣区域可以由用户选择或根据图像中的活动自动选择。

    AUTOMATIC ATHERECTOMY SYSTEM
    9.
    发明申请
    AUTOMATIC ATHERECTOMY SYSTEM 有权
    自动化系统

    公开(公告)号:US20110125172A1

    公开(公告)日:2011-05-26

    申请号:US12950871

    申请日:2010-11-19

    Abstract: An automatic atherectomy system uses a rotary burr at the tip of a catheter as a sensing device, in order to measure both electrical conductivity and permittivity of surrounding tissue at multiple frequencies. From these parameters it is determined which tissue lies in different directions around the tip. A servo system steers the catheter tip in the direction of the tissue to be removed. In non-atherectomy applications the rotary burr can be replaced with any desired tool and the system can be used to automatically steer the catheter to the desired position. The steering may be done hydraulically, by pressurizing miniature bellows located near the catheter tip.

    Abstract translation: 自动斑块切除术系统使用导管末端的旋转毛刺作为感测装置,以便测量多个频率的周围组织的电导率和介电常数。 根据这些参数,确定哪个组织位于尖端周围的不同方向。 伺服系统沿着要移除的组织的方向引导导管尖端。 在非粥样斑块切除术应用中,旋转毛刺可以用任何所需的工具代替,并且该系统可用于将导管自动转向所需位置。 通过对位于导管末端附近的微型波纹管进行加压,可以液压地进行转向。

    MEDICAL DEVICE, KIT AND METHOD FOR CONSTRICTING TISSUE OR A BODILY ORIFICE, FOR EXAMPLE, A MITRAL VALVE
    10.
    发明申请
    MEDICAL DEVICE, KIT AND METHOD FOR CONSTRICTING TISSUE OR A BODILY ORIFICE, FOR EXAMPLE, A MITRAL VALVE 审中-公开
    用于约束组织或身体组织的医疗装置,工具包和方法,例如,麻药阀

    公开(公告)号:US20110082538A1

    公开(公告)日:2011-04-07

    申请号:US12894912

    申请日:2010-09-30

    Abstract: A device, kit and method may include or employ an implantable device (e.g., annuloplasty implant) and a tool operable to implant such. The implantable device is positionable in a cavity of a bodily organ (e.g., a heart) and operable to constrict a bodily orifice (e.g., a mitral valve). The tissue anchors may be guided into precise position by an intravascularly or percutaneously deployed anchor guide frame of the tool and embedded in an annulus of the orifice. Constriction of the orifice may be accomplished via a variety of structures, for example by cinching a flexible cable or via a anchored annuloplasty ring, the cable or ring attached to the tissue anchors. The annuloplasty ring may be delivered in an unanchored, generally elongated configuration, and implanted in an anchored generally arch, arcuate or annular configuration. Such may approximate the septal and lateral (clinically referred to as anterior and posterior) annulus of the mitral valve, to move the posterior leaflet anteriorly and the anterior leaflet posteriorly, thereby improving leaflet coaptation to eliminate mitral regurgitation.

    Abstract translation: 装置,套件和方法可以包括或采用可植入装置(例如,瓣膜成形植入物)和可操作以植入其的工具。 可植入装置可定位在身体器官(例如,心脏)的空腔中并且可操作以收缩身体孔口(例如二尖瓣)。 组织锚固件可以通过工具的血管内或经皮部署的锚定引导框架被引导到精确位置,并且嵌入孔的环形空间中。 孔的收缩可以通过各种结构来实现,例如通过将柔性电缆束紧或经由锚定的瓣膜成形术环,连接到组织锚的电缆或环来实现。 瓣环成形术环可以以非锚定的,大体上细长的构造递送,并且以锚定的大致拱形,弓形或环形构型植入。 这可能近似于二尖瓣的间隔和外侧(临床称为前后)环,以向后移动后叶和前叶,从而改善小叶接合以消除二尖瓣反流。

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