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公开(公告)号：US07728097B2
公开(公告)日：2010-06-01
申请号：US11476513
申请日：2006-06-28
CPC分类号： C08G18/4252 , C08G18/771 , C08G2230/00
摘要： A novel macromer or mixture thereof is described herein, comprising benzoyl isocyanate terminal moieties and at least two residues of a water-soluble polymer having a molecular weight ranging from 80 to 10,000 adjacent to the carbonyl group of the benzoyl isocyanate moieties, thereby forming at least two ester linkages in the macromer or mixture thereof. A method for making a diisocyanate macromer is also described herein.
摘要翻译： 本文描述了一种新的大分子单体或其混合物，其包含苯甲酰异氰酸酯末端部分和与苯甲酰基异氰酸酯部分的羰基相邻的分子量范围为80至10,000的水溶性聚合物的至少两个残基，从而至少形成 大分子单体或其混合物中的两个酯键。 本文还描述了制备二异氰酸酯大分子单体的方法。
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2.发明申请MEDICALLY ACCEPTABLE FORMULATION OF A DIISOCYANATE TERMINATED MACROMER FOR USE AS AN INTERNAL ADHESIVE OR SEALANT 有权用作内部胶粘剂或密封剂的二异氰酸酯终止的MACROMER的医学上可接受的配方公开(公告)号：US20090222038A1
公开(公告)日：2009-09-03
申请号：US12415155
申请日：2009-03-31
CPC分类号： A61L24/0042 , A61L24/043 , A61L31/041 , A61L31/148 , C08G18/10 , C08G18/42 , C08L75/04
摘要： The present invention is directed to a medically acceptable formulation comprising a diisocyanate terminated macromer or mixture thereof, and bio-absorbable desiccant comprising a hygroscopic and/or hydrophilic or combination thereof. The present invention is also directed to methods of use for such formulations for medical procedures.
摘要翻译： 本发明涉及包含二异氰酸酯封端的大分子单体或其混合物的医学上可接受的制剂，以及包含吸湿性和/或亲水性或其组合的生物可吸收干燥剂。 本发明还涉及用于这种制剂用于医疗过程的方法。
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3.发明授权Medically acceptable formulation of a diisocyanate terminated macromer for use as an internal adhesive or sealant 有权用作内部粘合剂或密封剂的二异氰酸酯封端的大分子单体的医学上可接受的制剂公开(公告)号：US08071663B2
公开(公告)日：2011-12-06
申请号：US12415155
申请日：2009-03-31
CPC分类号： A61L24/0042 , A61L24/043 , A61L31/041 , A61L31/148 , C08G18/10 , C08G18/42 , C08L75/04
摘要： The present invention is directed to a medically acceptable formulation comprising a diisocyanate terminated macromer or mixture thereof, and bio-absorbable desiccant comprising a hygroscopic and/or hydrophilic or combination thereof. The present invention is also directed to methods of use for such formulations for medical procedures.
摘要翻译： 本发明涉及包含二异氰酸酯封端的大分子单体或其混合物的医学上可接受的制剂，以及包含吸湿性和/或亲水性或其组合的生物可吸收干燥剂。 本发明还涉及用于这种制剂用于医疗过程的方法。
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4.发明授权Diisocyanate terminated macromer and formulation thereof for use as an internal adhesive or sealant 有权二异氰酸酯封端的大分子单体及其制剂用作内部粘合剂或密封剂公开(公告)号：US08470954B2
公开(公告)日：2013-06-25
申请号：US11772401
申请日：2007-07-02
IPC分类号： C08G18/10
CPC分类号： C08G18/771 , A61L24/046 , C08G18/10 , C08G18/4252 , C08L75/04 , C08G18/42
摘要： A novel macromer or mixture thereof is described herein, comprising benzoyl isocyanate terminal moieties and at least two residues of a water-soluble polymer having a molecular weight ranging from 80 to 10,000 adjacent to the carbonyl group of the benzoyl isocyanate moieties, thereby forming at least two ester linkages in the macromer or mixture thereof. A method for making a polyisocyanate macromer is also described herein.
摘要翻译： 本文描述了一种新的大分子单体或其混合物，其包含苯甲酰异氰酸酯末端部分和与苯甲酰基异氰酸酯部分的羰基相邻的分子量范围为80至10,000的水溶性聚合物的至少两个残基，从而至少形成 大分子单体或其混合物中的两个酯键。 本文还描述了制备多异氰酸酯大分子单体的方法。
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5.发明授权Diisocyanate terminated macromer and formulation thereof for use as an internal adhesive or sealant 有权二异氰酸酯封端的大分子单体及其制剂用作内部粘合剂或密封剂公开(公告)号：US07968668B2
公开(公告)日：2011-06-28
申请号：US11476512
申请日：2006-06-28
CPC分类号： C08G18/771 , A61L24/046 , C07C265/14 , C08G18/10 , C08G18/4236 , C08G18/4252 , C08G18/4833 , C08G18/4887 , C08G18/7657 , C08G2190/00 , C08G2220/00 , C08G2230/00 , C09J175/06 , C09J175/08 , C08L75/04 , C08G18/307
摘要： A novel macromer or mixture thereof is described herein, comprising benzoyl isocyanate terminal moieties and at least two residues of a water-soluble polymer having a molecular weight ranging from 80 to 10,000 adjacent to the carbonyl group of the benzoyl isocyanate moieties, thereby forming at least two ester linkages in the macromer or mixture thereof. A method for making a polyisocyanate macromer is also described herein.
摘要翻译： 本文描述了一种新的大分子单体或其混合物，其包含苯甲酰异氰酸酯末端部分和与苯甲酰基异氰酸酯部分的羰基相邻的分子量范围为80至10,000的水溶性聚合物的至少两个残基，从而至少形成 大分子单体或其混合物中的两个酯键。 本文还描述了制备多异氰酸酯大分子单体的方法。
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