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公开(公告)号:US09671602B2
公开(公告)日:2017-06-06
申请号:US14239105
申请日:2012-08-09
申请人: Christine Schmidt , Bernd Srocka , Ralf Langhans
发明人: Christine Schmidt , Bernd Srocka , Ralf Langhans
CPC分类号: G02B21/14 , G01B9/04 , G01B11/0608
摘要: A method for optically measuring height profiles of surfaces, in which an image of the height profile is recorded using an optical recording system, is characterized in that the image is a differential interference contrast image and height gradients within the height profile are represented by intensity gradients, which are quantitatively or qualitatively evaluatable. The surfaces can have structures having a defined profile, in which intensity gradients in the differential interference contrast image, which assume, within a specified tolerance and within a specified range, a value which deviates from a predetermined value or assume a selected value from within a specified tolerance and within a specified range, indicate a defect.
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公开(公告)号:US20150174935A1
公开(公告)日:2015-06-25
申请号:US14139896
申请日:2013-12-24
申请人: Christine Schmidt
发明人: Christine Schmidt
摘要: A rubber ink stamping block for relief printing comprising a rigid central block having a first flat surface on a first side of said block and at least one rubber block secured thereto and preferably recessed from the outside edges thereof. The rubber block preferably comprises at least two opposing flat and parallel sides and is secured on a first flat side of the central block by adhesive or other fastening means. The rubber block is adapted to be carved on the exposed flat side by a carving tool in a conventional linoleum cut manner, creating depressions and land areas; the land areas between the depressions retaining ink and transferring the same when pressed onto a surface, like paper. Preferably, a second rubber block is provided also secured to the rigid block on the opposite side thereof from the first rubber block.
摘要翻译: 一种用于凸版印刷的橡胶油墨冲压块,包括刚性中心块,该刚性中心块在所述块的第一侧上具有第一平坦表面,并且至少一个橡胶块固定到其上,优选地从其外边缘凹入。 橡胶块优选地包括至少两个相对的平坦且平行的侧面,并且通过粘合剂或其它紧固装置固定在中心块的第一平坦侧上。 该橡胶块适用于通过雕刻工具以常规的亚麻油地切割方式在暴露的平坦侧上雕刻,形成凹陷和陆地区域; 凹陷之间的区域保持墨水并且当压在表面上时像纸一样将其转印。 优选地,也提供第二橡胶块,其与第一橡胶块的相对侧固定到刚性块。
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公开(公告)号:US20140242126A1
公开(公告)日:2014-08-28
申请号:US14277170
申请日:2014-05-14
申请人: Scott Zawko , Christine Schmidt
发明人: Scott Zawko , Christine Schmidt
IPC分类号: A61L26/00
CPC分类号: C08J9/26 , A61L26/0023 , A61L26/0095 , A61L27/52 , B01J13/0065 , C08B37/0015 , C08B37/003 , C08B37/0045 , C08B37/0072 , C08B37/0075 , C08B37/0084 , C08H1/06 , C08J3/075 , C08J3/24 , C08J3/242 , C08J3/26 , C08J3/28 , C08J5/10 , C08J5/18 , C08J2201/0424 , C08J2205/022 , C08J2205/04 , C08J2207/10 , C08J2305/00 , C08J2305/04 , C08J2305/08 , C08K5/0025 , C08K5/0083 , C08K5/21 , C08L5/00 , C08L5/04 , C08L5/10 , C08L5/16 , C08L89/06 , C08L5/06 , C08L5/08
摘要: The present invention includes a hydrogel and a method of making a porous hydrogel by preparing an aqueous mixture of an uncrosslinked polymer and a crystallizable molecule; casting the mixture into a vessel; allowing the cast mixture to dry to form an amorphous hydrogel film; seeding the cast mixture with a seed crystal of the crystallizable molecule; growing the crystallizable molecule into a crystal structure within the uncrosslinked polymer; crosslinking the polymer around the crystal structure under conditions in which the crystal structure within the crosslinked polymer is maintained; and dissolving the crystals within the crosslinked polymer to form the porous hydrogel.
摘要翻译: 本发明包括水凝胶和通过制备未交联聚合物和可结晶分子的水性混合物制备多孔水凝胶的方法; 将混合物浇铸成容器; 使铸造混合物干燥以形成无定形水凝胶膜; 用可结晶分子的晶种接种铸造混合物; 将可结晶分子生长成未交联的聚合物内的晶体结构; 在保持交联聚合物内的晶体结构的条件下使聚合物在晶体结构周围交联; 并将晶体溶解在交联聚合物中以形成多孔水凝胶。
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公开(公告)号:US08758794B2
公开(公告)日:2014-06-24
申请号:US12135772
申请日:2008-06-09
申请人: Christine Schmidt , Terry Hudson
发明人: Christine Schmidt , Terry Hudson
CPC分类号: A61L27/3633 , A61L27/3604 , A61L27/3675 , A61L27/3687 , A61L27/383 , A61L27/3878 , A61L2430/40
摘要: The present invention is a natural, cell-free tissue replacement that does not require difficult or extensive preparation made by washing tissue replacement in a solution including one or more sulfobetaines and an anionic surface-active detergent and washing the tissue replacement in serial solutions of the buffered salt to remove excess detergent. The natural, cell-free tissue replacement may be a nerve graft that supports axonal regeneration, guides the axons toward the distal nerve end and/or is immunologically tolerated. Other forms of the invention are a composition and kit prepared by the method of making a native, cell-free tissue replacement. The present invention may be modified for use in diagnostic, therapeutic, and prophylactic applications.
摘要翻译: 本发明是一种天然的无细胞组织替代物,其不需要通过在包括一种或多种磺基甜菜碱和阴离子表面活性洗涤剂的溶液中洗涤组织置换而制备的困难或广泛的制备,并且洗涤组织替换物 缓冲盐以除去多余的洗涤剂。 天然的无细胞组织置换可以是支持轴突再生的神经移植物,将轴突引导到远端神经末端和/或免疫耐受。 本发明的其它形式是通过制备天然的,无细胞的组织置换的方法制备的组合物和试剂盒。 本发明可以被修改用于诊断,治疗和预防应用。
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公开(公告)号:US08728499B2
公开(公告)日:2014-05-20
申请号:US13909707
申请日:2013-06-04
申请人: Scott Zawko , Christine Schmidt
发明人: Scott Zawko , Christine Schmidt
CPC分类号: C08J9/26 , A61L26/0023 , A61L26/0095 , A61L27/52 , B01J13/0065 , C08B37/0015 , C08B37/003 , C08B37/0045 , C08B37/0072 , C08B37/0075 , C08B37/0084 , C08H1/06 , C08J3/075 , C08J3/24 , C08J3/242 , C08J3/26 , C08J3/28 , C08J5/10 , C08J5/18 , C08J2201/0424 , C08J2205/022 , C08J2205/04 , C08J2207/10 , C08J2305/00 , C08J2305/04 , C08J2305/08 , C08K5/0025 , C08K5/0083 , C08K5/21 , C08L5/00 , C08L5/04 , C08L5/10 , C08L5/16 , C08L89/06 , C08L5/06 , C08L5/08
摘要: The present invention includes a hydrogel and a method of making a porous hydrogel by preparing an aqueous mixture of an uncrosslinked polymer and a crystallizable molecule; casting the mixture into a vessel; allowing the cast mixture to dry to form an amorphous hydrogel film; seeding the cast mixture with a seed crystal of the crystallizable molecule; growing the crystallizable molecule into a crystal structure within the uncrosslinked polymer; crosslinking the polymer around the crystal structure under conditions in which the crystal structure within the crosslinked polymer is maintained; and dissolving the crystals within the crosslinked polymer to form the porous hydrogel.
摘要翻译: 本发明包括水凝胶和通过制备未交联聚合物和可结晶分子的水性混合物制备多孔水凝胶的方法; 将混合物浇铸成容器; 使铸造混合物干燥以形成无定形水凝胶膜; 用可结晶分子的晶种接种铸造混合物; 将可结晶分子生长成未交联的聚合物内的晶体结构; 在保持交联聚合物内的晶体结构的条件下使聚合物在晶体结构周围交联; 并将晶体溶解在交联聚合物中以形成多孔水凝胶。
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公开(公告)号:US07402319B2
公开(公告)日:2008-07-22
申请号:US10672689
申请日:2003-09-26
申请人: Christine Schmidt , Terry Hudson
发明人: Christine Schmidt , Terry Hudson
IPC分类号: A61F2/02
CPC分类号: A61L27/3633 , A61L27/3604 , A61L27/3675 , A61L27/3687 , A61L27/383 , A61L27/3878 , A61L2430/40
摘要: The present invention is a natural, cell-free tissue replacement that does not require difficult or extensive preparation made by washing tissue replacement in a solution including one or more sulfobetaines and an anionic surface-active detergent and washing the tissue replacement in serial solutions of the buffered salt to remove excess detergent. The natural, cell-free tissue replacement may be a nerve graft that supports axonal regeneration, guides the axons toward the distal nerve end and/or is immunologically tolerated. Other forms of the invention are a composition and kit prepared by the method of making a native, cell-free tissue replacement. The present invention may be modified for use in diagnostic, therapeutic, and prophylactic applications.
摘要翻译: 本发明是一种天然的无细胞组织替代物,其不需要通过在包括一种或多种磺基甜菜碱和阴离子表面活性洗涤剂的溶液中洗涤组织置换而制备的困难或广泛的制备,并且洗涤组织替换物 缓冲盐以除去多余的洗涤剂。 天然的无细胞组织置换可以是支持轴突再生的神经移植物,将轴突引导到远端神经末端和/或免疫耐受。 本发明的其它形式是通过制备天然的,无细胞的组织置换的方法制备的组合物和试剂盒。 本发明可以被修改用于诊断,治疗和预防应用。
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公开(公告)号:US20150049348A1
公开(公告)日:2015-02-19
申请号:US14239105
申请日:2012-08-09
申请人: Christine Schmidt , Bernd Srocka , Ralf Langhans
发明人: Christine Schmidt , Bernd Srocka , Ralf Langhans
CPC分类号: G02B21/14 , G01B9/04 , G01B11/0608
摘要: A method for optically measuring height profiles of surfaces, in which an image of the height profile is recorded using an optical recording system, is characterized in that the image is a differential interference contrast image and height gradients within the height profile are represented by intensity gradients, which are quantitatively or qualitatively evaluatable. The surfaces can have structures having a defined profile, in which intensity gradients in the differential interference contrast image, which assume, within a specified tolerance and within a specified range, a value which deviates from a predetermined value or assume a selected value from within a specified tolerance and within a specified range, indicate a defect.
摘要翻译: 用于光学测量表面的高度分布的方法,其中使用光学记录系统记录高度分布的图像,其特征在于图像是差分干涉对比图像,并且高度分布内的高度梯度由强度梯度 ,其定量或定性可评估。 表面可以具有具有限定轮廓的结构,其中差分干涉对比图像中的强度梯度在指定的公差内和在指定范围内假设偏离预定值的值或者从 指定的公差并在指定的范围内,表示缺陷。
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公开(公告)号:US20050043819A1
公开(公告)日:2005-02-24
申请号:US10672689
申请日:2003-09-26
申请人: Christine Schmidt , Terry Hudson
发明人: Christine Schmidt , Terry Hudson
CPC分类号: A61L27/3633 , A61L27/3604 , A61L27/3675 , A61L27/3687 , A61L27/383 , A61L27/3878 , A61L2430/40
摘要: The present invention is a natural, cell-free tissue replacement that does not require difficult or extensive preparation made by washing tissue replacement in a solution including one or more sulfobetaines and an anionic surface-active detergent and washing the tissue replacement in serial solutions of the buffered salt to remove excess detergent. The natural, cell-free tissue replacement may be a nerve graft that supports axonal regeneration, guides the axons toward the distal nerve end and/or is immunologically tolerated. Other forms of the invention are a composition and kit prepared by the method of making a native, cell-free tissue replacement. The present invention may be modified for use in diagnostic, therapeutic, and prophylactic applications.
摘要翻译: 本发明是一种天然的无细胞组织替代物,其不需要通过在包括一种或多种磺基甜菜碱和阴离子表面活性洗涤剂的溶液中洗涤组织置换而制备的困难或广泛的制备,并且洗涤组织替换物 缓冲盐以除去多余的洗涤剂。 天然的无细胞组织置换可以是支持轴突再生的神经移植物,将轴突引导到远端神经末端和/或免疫耐受。 本发明的其它形式是通过制备天然的,无细胞的组织置换的方法制备的组合物和试剂盒。 本发明可以被修改用于诊断,治疗和预防应用。
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公开(公告)号:US20130266618A1
公开(公告)日:2013-10-10
申请号:US13909707
申请日:2013-06-04
申请人: Scott Zawko , Christine Schmidt
发明人: Scott Zawko , Christine Schmidt
CPC分类号: C08J9/26 , A61L26/0023 , A61L26/0095 , A61L27/52 , B01J13/0065 , C08B37/0015 , C08B37/003 , C08B37/0045 , C08B37/0072 , C08B37/0075 , C08B37/0084 , C08H1/06 , C08J3/075 , C08J3/24 , C08J3/242 , C08J3/26 , C08J3/28 , C08J5/10 , C08J5/18 , C08J2201/0424 , C08J2205/022 , C08J2205/04 , C08J2207/10 , C08J2305/00 , C08J2305/04 , C08J2305/08 , C08K5/0025 , C08K5/0083 , C08K5/21 , C08L5/00 , C08L5/04 , C08L5/10 , C08L5/16 , C08L89/06 , C08L5/06 , C08L5/08
摘要: The present invention includes a hydrogel and a method of making a porous hydrogel by preparing an aqueous mixture of an uncrosslinked polymer and a crystallizable molecule; casting the mixture into a vessel; allowing the cast mixture to dry to form an amorphous hydrogel film; seeding the cast mixture with a seed crystal of the crystallizable molecule; growing the crystallizable molecule into a crystal structure within the uncrosslinked polymer; crosslinking the polymer around the crystal structure under conditions in which the crystal structure within the crosslinked polymer is maintained; and dissolving the crystals within the crosslinked polymer to form the porous hydrogel.
摘要翻译: 本发明包括水凝胶和通过制备未交联聚合物和可结晶分子的水性混合物制备多孔水凝胶的方法; 将混合物浇铸成容器; 使铸造混合物干燥以形成无定形水凝胶膜; 用可结晶分子的晶种接种铸造混合物; 将可结晶分子生长成未交联的聚合物内的晶体结构; 在保持交联聚合物内的晶体结构的条件下使聚合物在晶体结构周围交联; 并将晶体溶解在交联聚合物中以形成多孔水凝胶。
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公开(公告)号:US20090030269A1
公开(公告)日:2009-01-29
申请号:US12135772
申请日:2008-06-09
申请人: Christine Schmidt , Terry Hudson
发明人: Christine Schmidt , Terry Hudson
CPC分类号: A61L27/3633 , A61L27/3604 , A61L27/3675 , A61L27/3687 , A61L27/383 , A61L27/3878 , A61L2430/40
摘要: The present invention is a natural, cell-free tissue replacement that does not require difficult or extensive preparation made by washing tissue replacement in a solution including one or more sulfobetaines and an anionic surface-active detergent and washing the tissue replacement in serial solutions of the buffered salt to remove excess detergent. The natural, cell-free tissue replacement may be a nerve graft that supports axonal regeneration, guides the axons toward the distal nerve end and/or is immunologically tolerated. Other forms of the invention are a composition and kit prepared by the method of making a native, cell-free tissue replacement. The present invention may be modified for use in diagnostic, therapeutic, and prophylactic applications.
摘要翻译: 本发明是一种天然的无细胞组织替代物,其不需要通过在包括一种或多种磺基甜菜碱和阴离子表面活性洗涤剂的溶液中洗涤组织置换而制备的困难或广泛的制备,并且洗涤组织替换物 缓冲盐以除去多余的洗涤剂。 天然的无细胞组织置换可以是支持轴突再生的神经移植物,将轴突引导到远端神经末端和/或免疫耐受。 本发明的其它形式是通过制备天然的,无细胞的组织替代物的方法制备的组合物和试剂盒。 本发明可以被修改用于诊断,治疗和预防应用。
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