公开(公告)号：US5795611A

公开(公告)日：1998-08-18

申请号：US453779

申请日：1989-12-20

申请人： Charles W. Slattery

发明人： Charles W. Slattery

IPC分类号： A23C11/06 ,  A23L1/29 ,  A23L1/305 ,  C07K14/47 ,  C07K14/76 ,  A23C9/00

CPC分类号： A23C11/065 ,  A23L33/19 ,  A23L33/40 ,  C07K14/4732 ,  C07K14/76 ,  Y10S426/801

摘要： A human infant formula sufficient to meet the nutritional requirements of a human infant, containing proteins having substantially the same amino acid sequence and biological properties as human alpha-lactalbumin and human beta-casein. The proteins may be produced from microorganisms, particularly E. coli. A recombinant DNA segment containing a human milk protein encoding gene; a promoter sequence directing the transcription of the gene, where the promoter sequence is different from the promoter sequence for the gene in the human organism; and a terminator site for the human milk protein encoding gene. A microorganism containing a recombinant DNA segment containing a human milk protein encoding gene; a promoter sequence directing the transcription of the gene; and a terminator site for the gene.

摘要翻译： 足以满足人类婴儿的营养需求的人类婴儿配方食品，其含有与人α-乳白蛋白和人β-酪蛋白基本上相同的氨基酸序列和生物学性质的蛋白质。 蛋白质可以由微生物，特别是大肠杆菌产生。 含有人乳蛋白编码基因的重组DNA片段; 引导基因转录的启动子序列，其中启动子序列不同于人类生物体中基因的启动子序列; 和用于人乳蛋白编码基因的终止位点。 含有含有人乳蛋白编码基因的重组DNA片段的微生物; 指导基因转录的启动子序列; 和该基因的终止位点。

公开(公告)号：US5942274A

公开(公告)日：1999-08-24

申请号：US100377

申请日：1998-06-19

申请人： Charles W. Slattery

发明人： Charles W. Slattery

IPC分类号： A23C11/06 ,  A23L1/29 ,  A23L1/305 ,  C07K14/47 ,  C07K14/76 ,  A23C9/00

CPC分类号： A23C11/065 ,  A23L33/19 ,  A23L33/40 ,  C07K14/4732 ,  C07K14/76 ,  Y10S426/801

摘要： A human infant formula sufficient to meet the nutritional requirements of a human infant, comprising proteins having substantially the same amino acid sequence and biological properties as human alpha-lactalbumin and human beta-casein. The proteins may be produced from microorganisms, particularly E. coli. A recombinant DNA segment comprising a human milk protein encoding gene; a promoter sequence directing the transcription of the gene, where the promoter sequence is different from the promoter sequence for the gene in the human organism; and a terminator site for the human milk protein encoding gene. A microorganism containing a recombinant DNA segment comprising a human milk protein encoding gene; a promoter sequence directing the transcription of the gene; and a terminator site for the gene.

摘要翻译： 一种足以满足人类婴儿的营养需求的人类婴儿配方食品，其包含具有与人α-乳白蛋白和人β-酪蛋白基本上相同的氨基酸序列和生物学特性的蛋白质。 蛋白质可以由微生物，特别是大肠杆菌产生。 包含人乳蛋白编码基因的重组DNA片段; 引导基因转录的启动子序列，其中启动子序列不同于人类生物体中基因的启动子序列; 和用于人乳蛋白编码基因的终止位点。 含有包含人乳蛋白编码基因的重组DNA片段的微生物; 指导基因转录的启动子序列; 和该基因的终止位点。