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公开(公告)号:US20240123017A1
公开(公告)日:2024-04-18
申请号:US18482014
申请日:2023-10-05
发明人: Tsong-Long Hwang , Yu-Chia Chang
IPC分类号: A61K36/898 , A61P17/02
CPC分类号: A61K36/898 , A61P17/02
摘要: A method for promoting chronic wound healing is provided, including administering an effective amount of Bletilla formosana (Hayata) Schltr. extract to a subject in need thereof, wherein the effective amount of Bletilla formosana (Hayata) Schltr. extract is 0.01 mg/kg-body weight to 100 mg/kg-body weight, and wherein the chronic wound including diabetic wound and Diabetic Foot Ulcer.
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公开(公告)号:US11839610B2
公开(公告)日:2023-12-12
申请号:US17806274
申请日:2022-06-10
发明人: Tsong-Long Hwang , Yu-Li Chen , Yu-Chia Chang
IPC分类号: A61K31/472 , A61P31/14 , C12N9/48 , A61K36/18
CPC分类号: A61K31/472 , A61K36/18 , A61P31/14 , C12N9/485 , C07K2319/30 , C12Y304/17023
摘要: A method for inhibiting infection of SARS-CoV-2 in a subject is provided, comprising administering an effective amount of plant extract, wherein the plant extract comprises an alcohol extract of the herbal of Menispermaceae, wherein the herbal of Menispermaceae is Stephania cepharantha or Stephania tetrandra.
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公开(公告)号:US20220163839A1
公开(公告)日:2022-05-26
申请号:US17132383
申请日:2020-12-23
发明人: Hsiu Min Tsai , Po Hsiang Huang
IPC分类号: G02F1/1335 , F21V8/00 , G02F1/13357
摘要: A robot using a liquid crystal display panel includes a mask, an LCD panel and a high-directional backlight module. The LCD is arranged close to the mask, and the backlight module is arranged on one side of the LCD panel and used to provide an extremely high directional backlight source to the liquid crystal display panel so that the image generated by the LCD panel can be projected onto the mask. By projecting images on the mask via the LCD panel, the disadvantage that the conventional projector needs to occupy a larger space is improved, and the design of the mask can be more flexible.
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公开(公告)号:US10654848B1
公开(公告)日:2020-05-19
申请号:US16185017
申请日:2018-11-09
IPC分类号: C07D407/02 , C07D471/04 , A61P11/00 , C07D498/04 , A61P17/06
摘要: Disclosed herein are compounds of formula (I), and pharmaceutical compositions comprising the same. The compounds of formula (I) are neutrophilic inflammation inhibitors, thus, they are useful for treatment and/or prophylaxis of inflammatory diseases and/or disorders associated with abnormal activation of neutrophils, such as ARDS, ALI, COPD, lung fibrosis, chronic bronchitis, pulmonary emphysema, α-1 anti-trypsin deficiency, cystic fibrosis, idiopathic pulmonary fibrosis, liver injury, steatohepatitis, liver fibrosis, damages caused by ischemia and reperfusion, myocardial infarction, shock, stroke, and organ transplantation, ulcerative cholitis, vasculitis, SLE, sepsis, SIRS, arthritis, psoriasis, atopic dermatitis, and inflammatory skin diseases.
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公开(公告)号:US20240282184A1
公开(公告)日:2024-08-22
申请号:US18442029
申请日:2024-02-14
发明人: I-Chen Yu , Yu-Ruei Chen
摘要: A nail clipper device including a lever, a lever cover, a main body, a first circuit board, a second circuit board, a connection assembly, and a nail cutter shell is provided. The lever cover is fitted over the lever, and the main body is connected to the lever, including a nail cutter. The first circuit board includes signal amplification circuit, alarm light module, and nail cutter electrode. The alarm light module is electrically connected to the signal amplification circuit, and the nail cutter electrode is electrically connected to the nail cutter. The second circuit board includes a finger electrode electrically connected to the signal amplification circuit. The connection assembly electrically connects the first and second circuit boards. The nail cutter shell features a finger reserved hole, positioned corresponding to the finger electrode. The nail clipper device is capable of preventing accidental injuries to the nail flesh during nail clipping.
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公开(公告)号:US20240269220A1
公开(公告)日:2024-08-15
申请号:US18566993
申请日:2022-03-24
发明人: Tsong-Long HWANG , Yu-Chia CHANG , Wu-Dai-Yu JIANG
IPC分类号: A61K36/898 , A61K31/05 , A61K31/085 , A61K31/09
CPC分类号: A61K36/898 , A61K31/05 , A61K31/085 , A61K31/09
摘要: Disclosed herein is a method of treating diseases and/or disorders associated with the dysregulated activation and recruitment of neutrophils. The method includes administering to a subject in need thereof an effective amount of an extract of Bletilla formosana. The Bletilla formosana extract includes, at least, compounds of 3,3′-dihydroxy-5-methoxybibenzyl (Batatacin III), 9,10-dihydro-1-[(4-hydroxyphenyl)methyl]-4-methoxy-2,7-phenanthrenediol (Orchidble), 3′,5-dimethoxy-3-hydroxybibenzyl (BF8-4-2), 3,5-dimethoxy-3′-hydroxybibenzyl (BF8-4-3) and 3-hydroxy-5-methoxybibenzyl (BF8-4-4).
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公开(公告)号:US20230390351A1
公开(公告)日:2023-12-07
申请号:US18154879
申请日:2023-01-16
IPC分类号: A61K36/29 , A61K31/4741 , A61P31/14
CPC分类号: A61K36/29 , A61K31/4741 , A61P31/14
摘要: A method for inhibiting infection of SARS-CoV-2 in a subject is provided, including administering to the subject a compound, wherein the compound comprises Aromoline, Obamegine, Berbamine or Bersavine.
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公开(公告)号:US20230321078A1
公开(公告)日:2023-10-12
申请号:US17806274
申请日:2022-06-10
发明人: Tsong-Long Hwang , Yu-Li Chen , Yu-Chia Chang
IPC分类号: A61K31/472 , C12N9/48 , A61P31/14 , A61K36/18
CPC分类号: A61K31/472 , C12N9/485 , A61P31/14 , A61K36/18 , C12Y304/17023 , C07K2319/30
摘要: A method for inhibiting infection of SARS-CoV-2 in a subject is provided, comprising administering an effective amount of plant extract, wherein the plant extract comprises an alcohol extract of the herbal of Menispermaceae, wherein the herbal of Menispermaceae is Stephania cepharantha or Stephania tetrandra.
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公开(公告)号:US20160129136A1
公开(公告)日:2016-05-12
申请号:US14932001
申请日:2015-11-04
发明人: Chia-Yu Fang , Chih-Jen Wen
IPC分类号: A61K49/00
CPC分类号: A61K49/0032 , A61K49/0082
摘要: Compositions comprising one or more nanoparticles, wherein the nanoparticles encapsulate fluorescence dyes are disclosed. In one embodiment, the nanoparticle comprises triterpene. In another embodiment, the nanoparticle comprises triterpene and fatty ester. Methods for performing a diagnostic or a therapeutic procedure comprising administering to a subject an effective amount of the compositions of the present invention or carbocyanine dyes are also provided.
摘要翻译: 公开了包含一种或多种纳米颗粒的组合物,其中纳米颗粒包封荧光染料。 在一个实施方案中,纳米颗粒包含三萜烯。 在另一个实施方案中,纳米颗粒包含三萜烯和脂肪酸酯。 还提供了用于进行诊断或治疗程序的方法,其包括向受试者施用有效量的本发明组合物或碳菁染料。
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公开(公告)号:US20200148674A1
公开(公告)日:2020-05-14
申请号:US16185017
申请日:2018-11-09
IPC分类号: C07D471/04 , A61P17/06 , C07D498/04 , A61P11/00
摘要: Disclosed herein are compounds of formula (I), and pharmaceutical compositions comprising the same. The compounds of formula (I) are neutrophilic inflammation inhibitors, thus, they are useful for treatment and/or prophylaxis of inflammatory diseases and/or disorders associated with abnormal activation of neutrophils, such as ARDS, ALI, COPD, lung fibrosis, chronic bronchitis, pulmonary emphysema, α-1 anti-trypsin deficiency, cystic fibrosis, idiopathic pulmonary fibrosis, liver injury, steatohepatitis, liver fibrosis, damages caused by ischemia and reperfusion, myocardial infarction, shock, stroke, and organ transplantation, ulcerative cholitis, vasculitis, SLE, sepsis, SIRS, arthritis, psoriasis, atopic dermatitis, and inflammatory skin diseases.
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