公开(公告)号：US20060105451A1

公开(公告)日：2006-05-18

申请号：US11316532

申请日：2005-12-21

申请人： Gregory Maine ,  Chandu Patel ,  Sanford Ginsburg ,  Timothy Bliese

发明人： Gregory Maine ,  Chandu Patel ,  Sanford Ginsburg ,  Timothy Bliese

IPC分类号： C12N15/74 ,  C07H21/04

CPC分类号： C07K14/45 ,  A61K39/00 ,  G01N33/56905 ,  G01N2333/45 ,  G01N2469/20 ,  Y10S435/975

摘要： The present invention relates to a genetically engineered P30 antigen and a combination or mixture of antigens (e.g., the genetically engineered P30 antigen and P35) that may be used in the detection of IgM and/or IgG antibodies to Toxoplasma gondii. Furthermore, the present invention also relates to methods of using this genetically engineered P30 antigen and combination of antigens, antibodies raised against this genetically engineered P30 antigen and combination of antigens, as well as kits and vaccines containing the genetically engineered P30 antigen and antigens present in the combination.

摘要翻译： 本发明涉及可用于检测弓形虫的IgM和/或IgG抗体的遗传工程化的P30抗原和抗原（例如，遗传工程化的P30抗原和P35）的组合或混合物。 此外，本发明还涉及使用这种遗传工程化的P30抗原和抗原组合，针对该遗传工程化的P30抗原产生的抗体和抗原组合的方法，以及含有遗传工程化的P30抗原的试剂盒和疫苗以及存在于 组合。