公开(公告)号：US5113019A

公开(公告)日：1992-05-12

申请号：US607224

申请日：1990-11-05

申请人： Catherine Vottero ,  Yves Labat ,  Jean-Marie Poirier

发明人： Catherine Vottero ,  Yves Labat ,  Jean-Marie Poirier

IPC分类号： C07B61/00 ,  B01J27/125 ,  B01J27/128 ,  C07C319/14 ,  C07C319/20 ,  C07C323/16 ,  C07C323/20 ,  C07C323/22

CPC分类号： C07C319/14 ,  C07C319/20

摘要： The invention relates to the preparation of alkylthiophenols by reaction of a dialkyl disulphide with a phenol.In the process according to the invention, the reaction is carried out in the presence of aluminum chloride or of ferric chloride in a solvent of the alkylbenzene type or, soley in the case of methylthiolation, in an excess of dimethyl disulphide.This process makes it possible, in particular to obtain, with a selectivity and in a yield which are excellent, 2-alkylthiophenols which may then be converted into 4-acyl-2-alkylthiophenols by means of a reaction at a temperature ranging from 40.degree. to 100.degree. C. with a complex BF.sub.3 :2RCOOH where R denotes an alkyl or propenyl radical, in a proportion of 10 to 15 moles of complex per mole of 2-alkylthiophenol.

摘要翻译： 本发明涉及通过二烷基二硫醚与苯酚的反应来制备烷基硫酚。 在根据本发明的方法中，反应在氯化铝或氯化铁存在下，在烷基苯类溶剂中或在甲硫醇化反应的情况下在过量二甲基二硫化物中进行。 该方法特别可以通过选择性和产率优异的2-烷基硫酚获得，然后可以通过在40℃的温度下反应转化成4-酰基-2-烷基硫酚 至100℃，其中R表示烷基或丙烯基，其摩尔比为10-35摩尔配合物/摩尔2-烷基苯硫酚。