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公开(公告)号:US20060253061A1
公开(公告)日:2006-11-09
申请号:US11112196
申请日:2005-04-22
IPC分类号: A61N1/30
CPC分类号: A61N1/30 , A61M2037/0007 , A61N1/0428 , A61N1/044
摘要: A disposable skin-worn device for the transdermal delivery at least one dose of charged therapeutic substances, including granisetron, by iontophoresis, the device comprising a donor reservoir containing an amount of a therapeutic substance to be delivered transdermally by iontophoresis, a counter reservoir, a source of electric power connected in a circuit between the donor reservoir and the counter reservoir and a control system for controlling current flow in the circuit to enable at least one dose of the therapeutic substance to be delivered transdermally by iontophoresis and wherein the control system includes a control element selected from the group consisting of a sensor activated by an external signal and a switch.
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公开(公告)号:US20060161132A1
公开(公告)日:2006-07-20
申请号:US10545761
申请日:2003-10-02
申请人: Carter Anderson , Russell Morris
发明人: Carter Anderson , Russell Morris
IPC分类号: A61M31/00
CPC分类号: A61N1/0436 , A61N1/044
摘要: An electrode assembly for use in an iontophoresis device for the transcutaneous administration of an active therapeutic species has a base layer of including a linking conductive base material which is consumed (oxidizes or reduces) preferentially to water, a first upper layer of sacrificial material coated on a first portion of the base layer wherein the sacrificial material is consumed preferentially to the linking conductive base material of the base layer. A second upper layer of non-conducting material is coated on a second portion of the base layer, the second upper layer being spaced from the first upper layer, connected by a narrow exposed linking area of the base layer material remaining exposed therebetween. During operation of an associated iontophoresis device, the sacrificial material will be sequentially consumed; the first upper layer will be fully consumed followed by the linking conductive base material of the exposed linking area of the base layer which severs the base layer thereby breaking circuit continuity disabling activity in the device. A visual indicator may be provided allowing a wearer to monitor the state of reaction of the linking area.
摘要翻译: 用于经皮给药活性治疗物种的离子电渗装置的电极组件具有包括优先吸收(氧化或还原)于水的连接导电基材的基层,涂覆在第一上层的牺牲材料 基底层的第一部分,其中牺牲材料优先地消耗到基底层的连接导电基底材料。 第二上层非导电材料被涂覆在基层的第二部分上,第二上层与第一上层隔开,第二上层由保留在其间的基层材料的窄暴露的连接区连接。 在相关联的离子电渗装置的操作期间,牺牲材料将被顺序消耗; 第一上层将被完全消耗,之后是基底层的暴露的连接区域的连接导电基底材料,其切断基底层,从而破坏器件中的电路连续性失效活动。 可以提供视觉指示器,允许佩戴者监视连接区域的反应状态。
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公开(公告)号:US5384031A
公开(公告)日:1995-01-24
申请号:US980086
申请日:1992-11-24
申请人: Carter Anderson , Kee V. Sin
发明人: Carter Anderson , Kee V. Sin
IPC分类号: G01N27/28 , G01N27/30 , G01N27/333 , G01N27/401
CPC分类号: G01N27/301
摘要: A reference electrode system for a disposable test cell which provides both a reference electrical potential and a liquid junction between the reference medium and an analytic or sample medium to which a sample is introduced to be tested includes a substrate carrying and supporting a thin metallic electrode layer, an hydrophilic medium overlays the electrodes, a portion connecting the metallic layer and the sample conducting medium to provide an electrical connection and free diffusion liquid junction with the sample medium, a liquid impermeable dielectric barrier layer sealing all but a selected, relatively minor portion of the hydrophilic medium exposed to contact the analytic medium. Electrolyte salts introduced into the free diffusion channel control both the reference electrode potential and the junction potential.
摘要翻译: 用于一次性测试电池的参考电极系统,其提供参考电位和参考介质与待测试样品所引入的分析或样品介质之间的液体接头,包括承载和支撑薄金属电极层的基板 ,亲水介质覆盖电极,连接金属层和样品导电介质的部分,以提供与样品介质的电连接和自由扩散液体接合;液体不可渗透的介电阻挡层,除了所选择的较小部分 暴露于亲水介质接触分析介质。 引入自由扩散通道的电解质盐控制参考电极电位和结电位。
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公开(公告)号:US2437671A
公开(公告)日:1948-03-16
申请号:US52192144
申请日:1944-02-11
申请人: CARTER ANDERSON JOHN
发明人: CARTER ANDERSON JOHN
IPC分类号: B03B5/38
CPC分类号: B03B5/38
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公开(公告)号:US5346604A
公开(公告)日:1994-09-13
申请号:US964583
申请日:1992-10-21
申请人: Kee Van Sin , Carter Anderson , Kellie Erbisch
发明人: Kee Van Sin , Carter Anderson , Kellie Erbisch
IPC分类号: G01N27/49 , G01N27/404
CPC分类号: G01N27/404
摘要: A gaseous oxygen electrochemical sensing system sustains inter-electrode ionic conductivity by the use of a combination of an hydrophilic coating layer on a gas-permeable barrier or separation membrane to supply sufficient moisture to the electrolyte of an electrode system to activate the sensor and sustain proper operation.
摘要翻译: 气态氧电化学感测系统通过使用透气屏障或分离膜上的亲水涂层的组合来维持电极间离子导电性,以向电极系统的电解质供应足够的水分以激活传感器并维持适当的 操作。
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公开(公告)号:US20050163717A1
公开(公告)日:2005-07-28
申请号:US10763628
申请日:2004-01-23
申请人: Carter Anderson , Russell Morris
发明人: Carter Anderson , Russell Morris
IPC分类号: A61K9/44 , A61K9/70 , A61K31/445 , A61K49/00
CPC分类号: A62D3/33 , A61J1/00 , A61J1/14 , A61K9/7084 , A61K31/445 , A62D3/00 , A62D2101/26 , B09B3/0075 , B09B2220/14 , B65D25/14
摘要: The potential for substance abuse involving residual amounts of abusable substances remaining in used skin-worn patches is reduced by the provision of a system and method for combining the abusable substance with a separate anti-abuse substance agent as part of a removal or disposal procedure.
摘要翻译: 通过提供将可滥用物质与单独的抗滥用物质试剂相结合的系统和方法作为去除或处理程序的一部分,减少了残留在使用过的皮肤磨损块中的残留量的可滥用物质的潜在可能性。
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