公开(公告)号：US20140264985A1

公开(公告)日：2014-09-18

申请号：US14352209

申请日：2012-10-18

申请人： CYTOMATRIX PTY LTD

发明人： Alessandra Sutti ,  Tong Lin ,  Mark Alexander Kirkland

IPC分类号： D01D5/40

CPC分类号： D01D5/40 ,  D01D5/06 ,  D01D5/26 ,  D01F1/10 ,  D01F4/02 ,  D01F6/16 ,  D01F6/22 ,  D01F6/30 ,  D01F6/36 ,  D01F6/625 ,  D01F9/00 ,  D04H1/4326

摘要： The present invention relates to a process for the preparation of fibres and fibres prepared by the process. The process can provide discontinuous colloidal polymer fibres in a process that employs a low viscosity dispersion medium.

摘要翻译： 本发明涉及通过该方法制备的纤维和纤维的制备方法。 该方法可以在使用低粘度分散介质的方法中提供不连续的胶体聚合物纤维。

公开(公告)号：US09518250B2

公开(公告)日：2016-12-13

申请号：US14346160

申请日：2012-09-21

申请人： CYTOMATRIX PTY LTD

发明人： Melinda L. Tursky ,  Mark. A. Kirkland

IPC分类号： A61K38/00 ,  C12N5/18 ,  C12N5/0789

CPC分类号： C12N5/0647 ,  C12N2501/125 ,  C12N2501/145 ,  C12N2501/22 ,  C12N2501/2306 ,  C12N2501/26 ,  C12N2501/59 ,  C12N2501/998

摘要： The present invention relates to hematopoietic cells, and more specifically to methods for long-term in vitro culturing and ex vivo expansion of hematopoietic cells. The present invention also provides compositions useful for culturing cells, such as media for culturing hematopoietic cells, specifically haematopoietic stem cells (HSC) and haematopoietic progenitor cells (HPC). The present invention further provides compositions including growth factor combinations and methods utilizing altered growth and environmental conditions that are applicable in vitro culturing and to ex vivo expansion of HSC and/or HPC.

摘要翻译： 本发明涉及造血细胞，更具体地涉及造血细胞的长期体外培养和离体扩增的方法。 本发明还提供了用于培养细胞的组合物，例如用于培养造血细胞的培养基，特别是造血干细胞（HSC）和造血祖细胞（HPC）。 本发明还提供包含生长因子组合的组合物和利用可用于HSC和/或HPC的体外培养和体外扩增的改变的生长和环境条件的方法。

公开(公告)号：US20140286915A1

公开(公告)日：2014-09-25

申请号：US14346160

申请日：2012-09-21

申请人： CYTOMATRIX PTY LTD

发明人： Melinda L. Tursky ,  Mark A. Kirkland

IPC分类号： C12N5/0789

CPC分类号： C12N5/0647 ,  C12N2501/125 ,  C12N2501/145 ,  C12N2501/22 ,  C12N2501/2306 ,  C12N2501/26 ,  C12N2501/59 ,  C12N2501/998

摘要： The present invention relates to hematopoietic cells, and more specifically to methods for long-term in vitro culturing and ex vivo expansion of hematopoietic cells. The present invention also provides compositions useful for culturing cells, such as media for culturing hematopoietic cells, specifically haematopoietic stem cells (HSC) and haematopoietic progenitor cells (HPC). The present invention further provides compositions including growth factor combinations and methods utilising altered growth and environmental conditions that are applicable in vitro culturing and to ex vivo expansion of HSC and/or HPC.

摘要翻译： 本发明涉及造血细胞，更具体地涉及造血细胞的长期体外培养和离体扩增的方法。 本发明还提供了用于培养细胞的组合物，例如用于培养造血细胞的培养基，特别是造血干细胞（HSC）和造血祖细胞（HPC）。 本发明还提供包含生长因子组合的组合物和利用可用于HSC和/或HPC的体外培养和体外扩增的改变的生长和环境条件的方法。