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公开(公告)号：US20250051795A1
公开(公告)日：2025-02-13
申请号：US18919922
申请日：2024-10-18
Inventor： Gregory B. MARTIN , Ari FEDER , Samantha MAINIERO , Sarah HIND , Diana Carolina MAZO MOLINA
Abstract: Embodiments of the disclosure are directed to compositions and methods for enhancing disease resistance in plants. One aspect of embodiments of the disclosure relates to a nucleic acid construct comprising a nucleic acid molecule comprising a Pseudomonas tomato race 1 (Ptr1) polynucleotide, a 5′ heterologous DNA promoter sequence, and a 3′ terminator sequence, wherein the nucleic acid molecule, the DNA promoter sequence, and the terminator sequence are operatively coupled to permit transcription of the nucleic acid molecule. Methods of imparting disease resistance to a plant and methods of identifying a candidate plant suitable for breeding that displays enhanced disease resistance are also disclosed. Embodiments of the disclosure also include plant cells, plants, and plant seeds including a heterologous Pseudomonas tomato race 1 (Ptr1) polynucleotide.
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公开(公告)号：US12180246B2
公开(公告)日：2024-12-31
申请号：US18208629
申请日：2023-06-12
Inventor： Andrea Choe , Paul W. Sternberg , Frank C. Schroeder , Stephan H. Von Reuss
IPC: A61K31/7028 , A01N37/36 , A01N43/16 , A01N43/38 , A61K31/454 , C07H15/04 , C07H15/08 , C07H15/10 , C07H15/18 , C07H15/26 , C07D309/10
Abstract: The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside.
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公开(公告)号：US11849688B2
公开(公告)日：2023-12-26
申请号：US17306166
申请日：2021-05-03
Inventor： Daniel F. Klessig , Frank Schroeder , Patricia Manosalva
CPC classification number: A01H3/04 , A01N43/16 , A01N43/38 , A01N63/10 , A01N63/12 , C12N15/8281 , C12N15/8282 , C12N15/8283 , C12N15/8285
Abstract: Compositions and methods for enhancing disease resistance in plants are disclosed.
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公开(公告)号：US11464810B2
公开(公告)日：2022-10-11
申请号：US16327670
申请日：2017-08-25
Inventor： Andrea Choe , Paul W. Sternberg , Frank C. Schroeder
IPC: A61K31/7028 , A61K35/62 , A61P1/04 , A61K31/4178 , A61K45/06 , A61P37/06 , A61P3/10 , A61K31/573 , G01N33/68 , A61K31/4439 , A61K31/56 , A61K31/7042 , A61K47/26
Abstract: A method of preventing or treating eosinophilic esophagitis (EoE) comprising administering a composition comprising ascr#7 is described.
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公开(公告)号：US11077151B2
公开(公告)日：2021-08-03
申请号：US16327659
申请日：2017-08-25
Inventor： Andrea Choe , Paul W. Sternberg , Frank C. Schroeder
IPC: A61K35/62 , A61P1/04 , A61K31/4178 , A61K31/7028 , A61K45/06 , A61P37/06 , A61P3/10 , A61K31/573 , G01N33/68 , A61K31/4439 , A61K31/56 , A61K31/7042 , A61K47/26
Abstract: The present invention relates to the use of ascr #7 for preventing or treating IL-6 and/or IL-1β-mediated diseases.
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Patent Agency Ranking
公开(公告)号：US11019776B2
公开(公告)日：2021-06-01
申请号：US16161252
申请日：2018-10-16
Inventor： Daniel Klessig , Frank Schroeder , Patricia Manosalva
Abstract: Compositions and methods for enhancing disease resistance in plants are disclosed.
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公开(公告)号：US20190192578A1
公开(公告)日：2019-06-27
申请号：US16327670
申请日：2017-08-25
Inventor： Andrea Choe , Paul W. Sternberg , Frank C. Schroeder
IPC: A61K35/62 , A61K31/4439 , A61K31/7042 , A61K31/56 , A61P1/04 , A61K31/4178 , A61K31/7028 , A61K47/26
CPC classification number: A61K35/62 , A61K31/4178 , A61K31/4439 , A61K31/56 , A61K31/573 , A61K31/7028 , A61K31/7042 , A61K45/06 , A61K47/26 , A61P1/04 , A61P3/10 , A61P37/06 , G01N33/6869 , Y02A50/414 , A61K2300/00
Abstract: A method of preventing or treating eosinophilic esophagitis (EoE) comprising administering a composition comprising ascr#7 is described.
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公开(公告)号：US20190059364A1
公开(公告)日：2019-02-28
申请号：US16119537
申请日：2018-08-31
Inventor： Angela SEARLE , Edward Guy Robert TURGEON , Joyce VAN ECK
IPC: A01N25/00 , C12N15/82 , A01N65/40 , C12N15/113
Abstract: A method involving administering to a phloem sap-feeding insect one or more dsRNAs capable of suppressing activity of one or more RNAi-suppressing nuclease genes expressed in the gut of the insect and one or more dsRNAs capable of suppressing one or more osmoregulatory genes expressed by the insect.
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公开(公告)号：US09879273B2
公开(公告)日：2018-01-30
申请号：US14657724
申请日：2015-03-13
Applicant: Boyce Thompson Institute for Plant Research
Inventor： Georg Jander , Tengfang Huang , Vijay Joshi
IPC: C12N15/82
CPC classification number: C12N15/8253 , C12N15/8218
Abstract: Compositions and methods are provided for increasing methionine content in plants are disclosed.
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10.发明申请公开(公告)号：US20150322537A1
公开(公告)日：2015-11-12
申请号：US14812803
申请日：2015-07-29
Inventor： Jocelyn Kenneth Rose , Tal Isaacson , Julia Vrebalov
IPC: C12Q1/68 , C07K14/415
CPC classification number: C07K14/415 , C12N15/8262 , C12N15/8266 , C12Q1/6895 , C12Q2600/13 , C12Q2600/156
Abstract: The present invention relates to an isolated nucleic acid molecule comprising a nucleotide sequence at least 90% identical to a nucleotide sequence encoding a protein having the amino acid sequence of SEQ ID NO:4, where the protein as an aspartic acid (Asp) at amino acid position 106. The present invention also relates to a transgenic plant with reduced or delayed softening and deterioration of fruit compared to wild-type plants, methods of genetic screening for plants having reduced or delayed softening and deterioration of fruit, isolated oligonucleotides, and a method of imparting to a plant the dfd trait.
Abstract translation: 本发明涉及分离的核酸分子，其包含与编码具有SEQ ID NO：4的氨基酸序列的蛋白质的核苷酸序列至少90％相同的核苷酸序列，其中作为氨基酸的天冬氨酸（Asp）的蛋白质 本发明还涉及与野生型植物相比具有降低的或延迟的软化和变质的转基因植物，具有减少或延迟的软化和延迟的果实，分离的寡核苷酸的植物的遗传筛选方法和 赋予植物dfd特征的方法。
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