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Patent Agency Ranking
公开(公告)号：US09090931B2
公开(公告)日：2015-07-28
申请号：US13811914
申请日：2011-08-09
Applicant: Haruyo Soya , Tomomi Murakami , Haruki Tsunoda , Yu Ohsugi , Ayako Yoda , Masashi Matsushita
Inventor： Haruyo Soya , Tomomi Murakami , Haruki Tsunoda , Yu Ohsugi , Ayako Yoda , Masashi Matsushita
Abstract: It is to provide a method for measuring glycated hemoglobin in a hemoglobin-containing sample, comprising: reacting glycated hemoglobin in the hemoglobin-containing sample with a proteolytic enzyme in the presence of at least one salt selected from the group consisting of a pyridinium salt, a phosphonium salt, an imidazolium salt, and an isoquinolinium salt; reacting the obtained reaction product with fructosyl peptide oxidase; and measuring the generated hydrogen peroxide. The present invention provides a method for accurately measuring glycated hemoglobin in a hemoglobin-containing sample.
Abstract translation: 本发明提供一种测定含血红蛋白的样品中的糖化血红蛋白的方法，其特征在于：在含有血红蛋白的样品中的糖化血红蛋白与蛋白水解酶反应，所述方法是在至少一种选自吡啶盐， 鏻盐，咪唑鎓盐和异喹啉鎓盐; 使得到的反应产物与果糖基肽氧化酶反应; 并测量所产生的过氧化氢。 本发明提供了一种在含血红蛋白的样品中精确测定糖化血红蛋白的方法。
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公开(公告)号：US20130115646A1
公开(公告)日：2013-05-09
申请号：US13811914
申请日：2011-08-09
Applicant: Haruyo Soya , Tomomi Murakami , Haruki Tsunoda , Yu Ohsugi , Ayako Yoda , Masashi Matsushita
Inventor： Haruyo Soya , Tomomi Murakami , Haruki Tsunoda , Yu Ohsugi , Ayako Yoda , Masashi Matsushita
IPC: C12Q1/37
Abstract: It is to provide a method for measuring glycated hemoglobin in a hemoglobin-containing sample, comprising: reacting glycated hemoglobin in the hemoglobin-containing sample with a proteolytic enzyme in the presence of at least one salt selected from the group consisting of a pyridinium salt, a phosphonium salt, an imidazolium salt, and an isoquinolinium salt; reacting the obtained reaction product with fructosyl peptide oxidase; and measuring the generated hydrogen peroxide. The present invention provides a method for accurately measuring glycated hemoglobin in a hemoglobin-containing sample.
Abstract translation: 本发明提供一种测定含血红蛋白的样品中的糖化血红蛋白的方法，其特征在于：在含有血红蛋白的样品中的糖化血红蛋白与蛋白水解酶反应，所述方法是在至少一种选自吡啶盐， 鏻盐，咪唑鎓盐和异喹啉盐; 使得到的反应产物与果糖基肽氧化酶反应; 并测量所产生的过氧化氢。 本发明提供了一种在含血红蛋白的样品中精确测定糖化血红蛋白的方法。
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公开(公告)号：US20130171676A1
公开(公告)日：2013-07-04
申请号：US13811911
申请日：2011-08-09
Applicant: Tomomi Murakami , Haruyo Soya , Yu Ohsugi , Ayako Yoda , Haruki Tsunoda , Masashi Matsushita
Inventor： Tomomi Murakami , Haruyo Soya , Yu Ohsugi , Ayako Yoda , Haruki Tsunoda , Masashi Matsushita
IPC: G01N33/72
CPC classification number: G01N33/723 , C12Q1/26 , C12Q1/37
Abstract: It is to provide a method for measuring glycated hemoglobin in a hemoglobin-containing sample, comprising reacting the hemoglobin-containing sample with a proteolytic enzyme in the presence of a surfactant, and then reacting the obtained reaction product with fructosyl peptide oxidase, wherein at least one of the former reaction and the latter reaction is performed in the presence of an isothiazolinone derivative; and measuring the generated hydrogen peroxide. The present invention provides a method for accurately and highly sensitively measuring glycated hemoglobin in a hemoglobin-containing sample without being influenced by hemoglobin.
Abstract translation: 提供一种测定含血红蛋白的样品中的糖化血红蛋白的方法，包括在表面活性剂存在下使含血红蛋白的样品与蛋白水解酶反应，然后使所得反应产物与果糖基肽氧化酶反应，其中至少 前一反应和后一反应之一在异噻唑啉酮衍生物的存在下进行; 并测量所产生的过氧化氢。 本发明提供了一种在不受血红蛋白影响的情况下，对含有血红蛋白的样品中的糖化血红蛋白进行准确高度敏感测定的方法。
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公开(公告)号：US20130123491A1
公开(公告)日：2013-05-16
申请号：US13811925
申请日：2011-08-09
Applicant: Haruyo Soya , Tomomi Murakami , Haruki Tsunoda , Yu Ohsugi , Ayako Yoda , Masashi Matsushita
Inventor： Haruyo Soya , Tomomi Murakami , Haruki Tsunoda , Yu Ohsugi , Ayako Yoda , Masashi Matsushita
IPC: C07D279/30
CPC classification number: C07D279/30 , C09B11/12 , C09B21/00 , C09B67/0077 , C09B67/0083 , C12Q1/28 , G01N33/723
Abstract: It is to provide a method for preserving an aqueous solution comprising a leuco chromogen, comprising adding at least one compound selected from the group consisting of polyoxyethylene alkylamine and polyoxyethylene alkenylamine to the aqueous solution containing a leuco chromogen, and a method for stabilizing a leuco chromogen, comprising allowing the leuco chromogen to coexist in an aqueous solution comprising at least one compound selected from the group consisting of polyoxyethylene alkylamine and polyoxyethylene alkenylamine. The present invention provides a method for preserving an aqueous solution comprising a leuco chromogen for stably preserving the leuco chromogen in an aqueous solution and a method for stabilizing a leuco chromogen.
Abstract translation: 本发明提供一种保存含有无色致发色素的水溶液的方法，该方法包括将至少一种选自聚氧乙烯烷基胺和聚氧乙烯链烯基胺的化合物加入到含有无色发色团的水溶液中，以及使无色发色体稳定的方法 包括使无色发色体共存于包含至少一种选自聚氧乙烯烷基胺和聚氧乙烯链烯基胺的化合物的水溶液中。 本发明提供了一种保存水溶液的方法，所述方法包括用于在水溶液中稳定保留无色发色团的无色发色体和稳定无色发色体的方法。
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公开(公告)号：US09493433B2
公开(公告)日：2016-11-15
申请号：US13811925
申请日：2011-08-09
Applicant: Haruyo Soya , Tomomi Murakami , Haruki Tsunoda , Yu Ohsugi , Ayako Yoda , Masashi Matsushita
Inventor： Haruyo Soya , Tomomi Murakami , Haruki Tsunoda , Yu Ohsugi , Ayako Yoda , Masashi Matsushita
IPC: C09B21/00 , C09B67/00 , C09B67/42 , C07D279/30 , C09B67/28 , C09B67/44 , C12Q1/28 , G01N33/72 , C09B11/12
CPC classification number: C07D279/30 , C09B11/12 , C09B21/00 , C09B67/0077 , C09B67/0083 , C12Q1/28 , G01N33/723
Abstract: Described is a method for preserving an aqueous solution comprising a leuco chromogen, comprising adding at least one compound selected from the group consisting of polyoxyethylene alkylamine and polyoxyethylene alkenylamine to the aqueous solution containing a leuco chromogen, and a method for stabilizing a leuco chromogen, comprising allowing the leuco chromogen to coexist in an aqueous solution comprising at least one compound selected from the group consisting of polyoxyethylene alkylamine and polyoxyethylene alkenylamine.
Abstract translation: 描述了一种保存含有无色致发色素的水溶液的方法，包括将至少一种选自聚氧乙烯烷基胺和聚氧乙烯链烯基胺的化合物加入到含有无色致发色素的水溶液中，以及一种稳定无色发色体的方法，包括 允许无色发色体共存于包含至少一种选自聚氧乙烯烷基胺和聚氧乙烯链烯基胺的化合物的水溶液中。
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