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公开(公告)号：US08536183B2
公开(公告)日：2013-09-17
申请号：US13568211
申请日：2012-08-07
Applicant: Paul John Beswick , Alister Campbell , Andrew Cridland , Robert James Gleave , Jag Paul Heer , Neville Hubert Nicholson , Lee William Page , Sadie Vile
Inventor： Paul John Beswick , Alister Campbell , Andrew Cridland , Robert James Gleave , Jag Paul Heer , Neville Hubert Nicholson , Lee William Page , Sadie Vile
IPC: A61K31/496 , C07D401/06
CPC classification number: C07D213/81
Abstract: The present invention relates to novel piperazine derivatives; to processes for their preparation; to pharmaceutical compositions containing the derivatives; and to the use of the derivatives in therapy to treat diseases for which blocking the Cav2.2 calcium channels is beneficial.
Abstract translation: 本发明涉及新的哌嗪衍生物; 进行准备; 含有该衍生物的药物组合物; 以及在治疗中使用衍生物治疗阻断Cav2.2钙通道有益的疾病。
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公开(公告)号：US20120302746A1
公开(公告)日：2012-11-29
申请号：US13568211
申请日：2012-08-07
Applicant: Paul John Beswick , Alister Campbell , Andrew Cridland , Robert James Gleave , Jag Paul Heer , Neville Hubert Nicholson , Lee William Page , Sadie Vile
Inventor： Paul John Beswick , Alister Campbell , Andrew Cridland , Robert James Gleave , Jag Paul Heer , Neville Hubert Nicholson , Lee William Page , Sadie Vile
IPC: C07D401/06 , C07D401/14 , C07D405/14 , C07D413/14
CPC classification number: C07D213/81
Abstract: The present invention relates to novel piperazine derivatives; to processes for their preparation; to pharmaceutical compositions containing the derivatives; and to the use of the derivatives in therapy to treat diseases for which blocking the Cav2.2 calcium channels is beneficial.
Abstract translation: 本发明涉及新的哌嗪衍生物; 进行准备; 含有该衍生物的药物组合物; 以及在治疗中使用衍生物治疗阻断Cav2.2钙通道有益的疾病。
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公开(公告)号：US20100022555A1
公开(公告)日：2010-01-28
申请号：US12503125
申请日：2009-07-15
Applicant: Paul John Beswick , Alister Campbell , Andrew Cridland , Robert James Gleave , Jag Paul Heer , Neville Hubert Nicholson , Lee William Page , Sadie Vile
Inventor： Paul John Beswick , Alister Campbell , Andrew Cridland , Robert James Gleave , Jag Paul Heer , Neville Hubert Nicholson , Lee William Page , Sadie Vile
IPC: A61K31/497 , C07D401/06 , A61P25/00 , A61P29/00
CPC classification number: C07D213/81
Abstract: The present invention relates to novel piperazine derivatives; to processes for their preparation; to pharmaceutical compositions containing the derivatives; and to the use of the derivatives in therapy to treat diseases for which blocking the Cav2.2 calcium channels is beneficial.
Abstract translation: 本发明涉及新型哌嗪衍生物; 进行准备; 含有该衍生物的药物组合物; 以及在治疗中使用衍生物治疗阻断Cav2.2钙通道有益的疾病。
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公开(公告)号：US08288388B2
公开(公告)日：2012-10-16
申请号：US12503125
申请日：2009-07-15
Applicant: Paul John Beswick , Alister Campbell , Andrew Cridland , Robert James Gleave , Jag Paul Heer , Neville Hubert Nicholson , Lee William Page , Sadie Vile
Inventor： Paul John Beswick , Alister Campbell , Andrew Cridland , Robert James Gleave , Jag Paul Heer , Neville Hubert Nicholson , Lee William Page , Sadie Vile
IPC: A61K31/496 , C07D401/06
CPC classification number: C07D213/81
Abstract: The present invention relates to novel piperazine derivatives; to processes for their preparation; to pharmaceutical compositions containing the derivatives; and to the use of the derivatives in therapy to treat diseases for which blocking the Cav2.2 calcium channels is beneficial.
Abstract translation: 本发明涉及新的哌嗪衍生物; 进行准备; 含有该衍生物的药物组合物; 以及在治疗中使用衍生物治疗阻断Cav2.2钙通道有益的疾病。
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