公开(公告)号：US06794670B1

公开(公告)日：2004-09-21

申请号：US09674764

申请日：2000-11-03

申请人： Staffan Folestad ,  Mats Josefson ,  Anders Sparén ,  Jonas Johansson

发明人： Staffan Folestad ,  Mats Josefson ,  Anders Sparén ,  Jonas Johansson

IPC分类号： G01N2161

CPC分类号： G01N21/47 ,  G01J3/4412 ,  G01N21/33 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/51 ,  G01N21/532 ,  G01N21/534 ,  G01N2021/399

摘要： The present invention relates to a method and an apparatus for use in performing a quantitative analysis of a turbid pharmaceutical sample, e.g. a tablet, a capsule or a similar sample forming a pharmaceutical dose. A pharmaceutical, turbid sample (24) is irradiated with an excitation beam (20) of radiation, e.g. near infrared radiation. The intensity of emitted radiation (30) from the sample (24) is detected as a function of both the wavelength of the emitted radiation and the photon propagation time through said sample (24). Optionally, the intensity of the emitted radiation (30) from the sample (24) is also detected in a spatially resolved manner.

摘要翻译： 本发明涉及用于对混浊药物样品进行定量分析的方法和装置，例如， 片剂，胶囊或形成药物剂量的类似样品。 药物混浊样品（24）用辐射的激发光束（20）照射，例如， 近红外辐射。 根据所发射的辐射的波长和通过所述样品（24）的光子传播时间两者，检测来自样品（24）的发射辐射（30）的强度。 可选地，来自样品（24）的发射辐射（30）的强度也以空间分辨的方式检测。

公开(公告)号：US06354145B1

公开(公告)日：2002-03-12

申请号：US09355297

申请日：1999-07-28

申请人： Magnus Fransson ,  Lars Karlsson ,  Bengt Lagerholm ,  Anders Sparén

发明人： Magnus Fransson ,  Lars Karlsson ,  Bengt Lagerholm ,  Anders Sparén

IPC分类号： G01N3108

CPC分类号： G01N30/8651 ,  G01N30/8658 ,  G01N30/8682 ,  G01N2030/8804 ,  G01N2030/8886 ,  G01N2201/129

摘要： The present invention relates to a method for analyzing mixtures of components by a process selected from the group consisting of flow based separation processes and flow analysis processes. The method comprising the steps of: obtaining measurement signals by measuring process conditions at a plurality of positions throughout the system; applying signal processing to the measurement signals, said signal processing comprising multivariate data analysis for condensing the plurality of measurement signals to a smaller number of main signals being non-correlated; logging said main signals; and displaying said main signals versus time, where changes of said system conditions are indicated by one or more of the displayed main signals; detecting any error occurrence during an on going process, and determining what part of said system cause said error.

摘要翻译： 本发明涉及通过选自流体分离方法和流动分析方法的方法分析组分混合物的方法。 该方法包括以下步骤：通过测量整个系统中的多个位置处的处理条件来获得测量信号;对测量信号应用信号处理，所述信号处理包括多变量数据分析，用于将多个测量信号冷凝到较小数量的 主信号不相关;记录主信号; 以及显示所述主信号与时间的关系，其中所述系统条件的变化由所显示的主信号中的一个或多个指示;检测正在进行的过程中的任何错误发生，以及确定所述系统的哪一部分引起所述错误。