公开(公告)号：US09931196B2

公开(公告)日：2018-04-03

申请号：US15245873

申请日：2016-08-24

申请人： ALBERT EINSTEIN HEALTHCARE NETWORK

发明人： Minn Saing

IPC分类号： A61F2/08

CPC分类号： A61F2/0811 ,  A61F2002/0835 ,  A61F2002/0858 ,  A61F2002/0882

摘要： A connector for attaching a connective tissue to bone includes a sling for supporting and holding the connective tissue. A trap generally cooperates with the sling. The trap includes an anchor end and a sling end and a generally tubular section configured to decrease in diameter upon application of a longitudinal tensile force. The trap is dimensioned to fit within a tunnel through bone so that the connective tissue emerges from one end of the tunnel and so that an interference screw can be inserted into the tubular section at the anchor end of the trap at the other end of the tunnel whereby a pulling force exerted on the sling causes the generally tubular section of the trap to constrict more tightly about the interference screw to prevent slippage and to deter withdrawal of the trap from the tunnel.

公开(公告)号：US09295398B2

公开(公告)日：2016-03-29

申请号：US14467495

申请日：2014-08-25

申请人： Albert Einstein Healthcare Network

发明人： Allan M. Greenspan

IPC分类号： A61B5/0408 ,  A61B5/0452 ,  A61B5/053 ,  A61B5/0464 ,  A61B18/18 ,  A61B18/14 ,  A61B18/00 ,  A61B5/06

CPC分类号： A61B5/0452 ,  A61B5/0408 ,  A61B5/0464 ,  A61B5/0538 ,  A61B5/062 ,  A61B18/1492 ,  A61B18/18 ,  A61B2018/0016 ,  A61B2018/00357 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B2018/00875

摘要： A method and system for determining the mechanism of cardiac arrhythmia in a patient is disclosed. The method basically entails measuring the impedance of cardiac tissue in a portion of the patient's heart using a catheter during an episode of supraventricular tachycardia to produce an iso-impedance map of that cardiac tissue on a video display and analyzing the pattern of the iso-impedance map to differentiate focal arrhythmia caused by a circumscribed region of focal firing and reentrant arrhythmia caused by a macroreentrant circuit. The method can also be used to identify regions of coherent rapidly conducting tissue e.g., Bachman's bundle or the inferoposterior pathway insertion points, to identify focal “mother rotors” throughout the left atrium that may participate in the generation and maintenance of atrial fibrillation and to identify areas of CAFE (complex atrial/fractionated electrograms) that truly reflect these mother rotors.

摘要翻译： 公开了一种用于确定患者心律失常机制的方法和系统。 该方法基本上需要在室上性心动过速发作期间使用导管测量患者心脏的一部分中的心脏组织的阻抗，以在视频显示器上产生该心脏组织的等阻抗图，并分析等阻抗的模式 映射以区分由大面积电路引起的局灶性烧伤的外切区域和可重入心律失常引起的局灶性心律失常。 该方法还可以用于识别相干快速传导组织的区域，例如巴赫曼氏束或前后路径插入点，以识别整个左心房中可能参与心房颤动的产生和维持的局部“母体转子”，并且识别 真正反映这些母体转子的CAFE（复杂心房/分级电图）的区域。

公开(公告)号：US20150148642A1

公开(公告)日：2015-05-28

申请号：US14614051

申请日：2015-02-04

申请人： Albert Einstein Healthcare Network ,  The Trustees of the University of Pennsylvania

发明人： Allan M. Greenspan ,  Yale E. Goldman

IPC分类号： A61B5/042 ,  A61B5/00

CPC分类号： A61B5/042 ,  A61B5/0538 ,  A61B5/6852 ,  A61B2562/0209

摘要： Catheter systems for measuring at least one electrical property, e.g., impedance, of cardiac tissue of a living being are disclosed. The system includes a catheter having a tip with a sensing electrode, a guard electrode and an electrical shield. The sensing electrode is arranged to engage the cardiac tissue and is coupled to circuitry for measuring the at least one electrical property of the cardiac tissue, shielding the sensing electrode from bulk blood adjacent the cardiac tissue. The measurement can gated to the cardiac cycle. Additional embodiments include multi-electrode sensor catheter tips for high density mapping. Moreover, such tips may be dynamically configurable, i.e., their electrodes can be variably assigned as sensor electrodes or guard electrodes by associated circuitry. Such multi-electrode configuration and reconfiguration can be gated to the cardiac cycle.

摘要翻译： 公开了用于测量活体心脏组织的至少一种电性质（例如阻抗）的导管系统。 该系统包括具有带有感测电极的尖端的导管，保护电极和电屏蔽。 感测电极布置成接合心脏组织并且耦合到用于测量心脏组织的至少一个电性质的电路，从而屏蔽感测电极与邻近心脏组织的体积血液。 测量可以选择心脏周期。 另外的实施例包括用于高密度映射的多电极传感器导管尖端。 此外，这些尖端可以是可动态配置的，即，它们的电极可以通过相关联的电路被可变地分配为传感器电极或保护电极。 这种多电极配置和重构可以选择心脏周期。

公开(公告)号：US08977334B2

公开(公告)日：2015-03-10

申请号：US14091423

申请日：2013-11-27

申请人： Albert Einstein Healthcare Network ,  The Trustees of the University of Pennsylvania

发明人： Allan M. Greenspan ,  Yale E. Goldman

IPC分类号： A61B5/042 ,  A61B5/053 ,  A61B5/0428

CPC分类号： A61B5/042 ,  A61B5/0538 ,  A61B5/6852 ,  A61B2562/0209

摘要： Catheter systems for measuring at least one electrical property, e.g., impedance, of cardiac tissue of a living being are disclosed. The system includes a catheter having a tip with a sensing electrode, a guard electrode and an electrical shield. The sensing electrode is arranged to engage the cardiac tissue and is coupled to circuitry for measuring the at least one electrical property of the cardiac tissue, shielding the sensing electrode from bulk blood adjacent the cardiac tissue. The measurement can gated to the cardiac cycle. Additional embodiments include multi-electrode sensor catheter tips for high density mapping. Moreover, such tips may be dynamically configurable, i.e., their electrodes can be variably assigned as sensor electrodes or guard electrodes by associated circuitry. Such multi-electrode configuration and reconfiguration can be gated to the cardiac cycle.

摘要翻译： 公开了用于测量活体的心脏组织的至少一种电性质（例如阻抗）的导管系统。 该系统包括具有带有感测电极的尖端的导管，保护电极和电屏蔽。 感测电极布置成接合心脏组织并且耦合到用于测量心脏组织的至少一个电性质的电路，从而屏蔽感测电极与邻近心脏组织的体积血液。 测量可以选择心脏周期。 另外的实施例包括用于高密度映射的多电极传感器导管尖端。 此外，这些尖端可以是可动态配置的，即，它们的电极可以通过相关联的电路被可变地分配为传感器电极或保护电极。 这种多电极配置和重构可以选择心脏周期。

公开(公告)号：US08849384B2

公开(公告)日：2014-09-30

申请号：US14132814

申请日：2013-12-18

申请人： Albert Einstein Healthcare Network

发明人： Allan M. Greenspan

IPC分类号： A61B5/0408 ,  A61B18/18 ,  A61B5/0452 ,  A61B5/053 ,  A61B5/0464 ,  A61B18/00 ,  A61B5/06 ,  A61B18/14

CPC分类号： A61B5/0452 ,  A61B5/0408 ,  A61B5/0464 ,  A61B5/0538 ,  A61B5/062 ,  A61B18/1492 ,  A61B18/18 ,  A61B2018/0016 ,  A61B2018/00357 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B2018/00875

摘要： A method and system for determining the mechanism of cardiac arrhythmia in a patient is disclosed. The method basically entails measuring the impedance of cardiac tissue in a portion of the patient's heart using a catheter during an episode of supraventricular tachycardia to produce an iso-impedance map of that cardiac tissue on a video display and analyzing the pattern of the iso-impedance map to differentiate focal arrhythmia caused by a circumscribed region of focal firing and reentrant arrhythmia caused by a macroreentrant circuit. The method can also be used to identify regions of coherent rapidly conducting tissue e.g., Bachman's bundle or the inferoposterior pathway insertion points, to identify focal “mother rotors” throughout the left atrium that may participate in the generation and maintenance of atrial fibrillation and to identify areas of CAFE (complex atrial/fractionated electrograms) that truly reflect these mother rotors.

摘要翻译： 公开了一种用于确定患者心律失常机制的方法和系统。 该方法基本上需要在室上性心动过速发作期间使用导管测量患者心脏的一部分中的心脏组织的阻抗，以在视频显示器上产生该心脏组织的等阻抗图，并分析等阻抗的模式 映射以区分由大面积电路引起的局灶性烧伤的外切区域和可重入心律失常引起的局灶性心律失常。 该方法还可以用于识别相干快速传导组织的区域，例如巴赫曼氏束或前后路径插入点，以识别整个左心房中可能参与心房颤动的产生和维持的局部“母体转子”，并且识别 真正反映这些母体转子的CAFE（复杂心房/分级电图）的区域。

公开(公告)号：US20140155722A1

公开(公告)日：2014-06-05

申请号：US14091423

申请日：2013-11-27

申请人： The Trustees of the University of Pennsylvania ,  Albert Einstein Healthcare Network

发明人： Allan M. Greenspan ,  Yale E. Goldman

IPC分类号： A61B5/053

CPC分类号： A61B5/042 ,  A61B5/0538 ,  A61B5/6852 ,  A61B2562/0209

摘要： Catheter systems for measuring at least one electrical property, e.g., impedance, of cardiac tissue of a living being are disclosed. The system includes a catheter having a tip with a sensing electrode, a guard electrode and an electrical shield. The sensing electrode is arranged to engage the cardiac tissue and is coupled to circuitry for measuring the at least one electrical property of the cardiac tissue, shielding the sensing electrode from bulk blood adjacent the cardiac tissue. The measurement can gated to the cardiac cycle. Additional embodiments include multi-electrode sensor catheter tips for high density mapping. Moreover, such tips may be dynamically configurable, i.e., their electrodes can be variably assigned as sensor electrodes or guard electrodes by associated circuitry. Such multi-electrode configuration and reconfiguration can be gated to the cardiac cycle.

摘要翻译： 公开了用于测量活体的心脏组织的至少一种电性质（例如阻抗）的导管系统。 该系统包括具有带有感测电极的尖端的导管，保护电极和电屏蔽。 感测电极布置成接合心脏组织并且耦合到用于测量心脏组织的至少一个电性质的电路，从而屏蔽感测电极与邻近心脏组织的体积血液。 测量可以选择心脏周期。 另外的实施例包括用于高密度映射的多电极传感器导管尖端。 此外，这些尖端可以是可动态配置的，即，它们的电极可以通过相关联的电路被可变地分配为传感器电极或保护电极。 这种多电极配置和重构可以选择心脏周期。

公开(公告)号：US20170056158A1

公开(公告)日：2017-03-02

申请号：US15245873

申请日：2016-08-24

申请人： ALBERT EINSTEIN HEALTHCARE NETWORK

发明人： Minn Saing

IPC分类号： A61F2/08

CPC分类号： A61F2/0811 ,  A61F2002/0835 ,  A61F2002/0858 ,  A61F2002/0882

摘要： A connector for attaching a connective tissue to bone includes a sling for supporting and holding the connective tissue. A trap generally cooperates with the sling. The trap includes an anchor end and a sling end and a generally tubular section configured to decrease in diameter upon application of a longitudinal tensile force. The trap is dimensioned to fit within a tunnel through bone so that the connective tissue emerges from one end of the tunnel and so that an interference screw can be inserted into the tubular section at the anchor end of the trap at the other end of the tunnel whereby a pulling force exerted on the sling causes the generally tubular section of the trap to constrict more tightly about the interference screw to prevent slippage and to deter withdrawal of the trap from the tunnel.

摘要翻译： 用于将结缔组织附接到骨头的连接器包括用于支撑和保持结缔组织的吊带。 陷阱通常与吊索配合。 捕集器包括锚定端和吊索端，以及大致管状部分，其构造成在施加纵向张力时直径减小。 捕集器的尺寸设计成适合穿过骨骼的隧道，使得结缔组织从隧道的一端出来，从而可以在隧道的另一端处将疏水螺钉插入陷阱的锚定端处的管状部分 由此施加在吊索上的拉力导致收集器的大致管状部分围绕该干涉螺钉更紧密地收缩，以防止滑动并阻止该收集器从隧道中的撤出。

公开(公告)号：US08655427B1

公开(公告)日：2014-02-18

申请号：US13689069

申请日：2012-11-29

申请人： Albert Einstein Healthcare Network ,  The Trustees of the University of Pennsylvania

发明人： Allan M. Greenspan ,  Yale E. Goldman

IPC分类号： A61B5/042 ,  A61B5/053 ,  A61B5/0428

CPC分类号： A61B5/042 ,  A61B5/0538 ,  A61B5/6852 ,  A61B2562/0209

摘要： Catheter systems for measuring at least one electrical property, e.g., impedance, of cardiac tissue of a living being are disclosed. The system includes a catheter having a tip with a sensing electrode, a guard electrode and an electrical shield. The sensing electrode is arranged to engage the cardiac tissue and is coupled to circuitry for measuring the at least one electrical property of the cardiac tissue, shielding the sensing electrode from bulk blood adjacent the cardiac tissue. The measurement can gated to the cardiac cycle. Additional embodiments include multi-electrode sensor catheter tips for high density mapping. Moreover, such tips may be dynamically configurable, i.e., their electrodes can be variably assigned as sensor electrodes or guard electrodes by associated circuitry. Such multi-electrode configuration and reconfiguration can be gated to the cardiac cycle.

摘要翻译： 公开了用于测量活体的心脏组织的至少一种电性质（例如阻抗）的导管系统。 该系统包括具有带有感测电极的尖端的导管，保护电极和电屏蔽。 感测电极布置成接合心脏组织并且耦合到用于测量心脏组织的至少一个电性质的电路，从而屏蔽感测电极与邻近心脏组织的体积血液。 测量可以选择心脏周期。 另外的实施例包括用于高密度映射的多电极传感器导管尖端。 此外，这样的尖端可以是可动态配置的，即，它们的电极可以通过相关联的电路被可变地分配为传感器电极或保护电极。 这种多电极配置和重构可以选择心脏周期。

公开(公告)号：US10251745B2

公开(公告)日：2019-04-09

申请号：US15901425

申请日：2018-02-21

申请人： ALBERT EINSTEIN HEALTHCARE NETWORK

发明人： Minn Saing

IPC分类号： A61F2/08

摘要： A connector for attaching a connective tissue to bone includes a sling for supporting and holding the connective tissue. A trap generally cooperates with the sling. The trap includes an anchor end and a sling end and a generally tubular section configured to decrease in diameter upon application of a longitudinal tensile force. The trap is dimensioned to fit within a tunnel through bone so that the connective tissue emerges from one end of the tunnel and so that an interference screw can be inserted into the tubular section at the anchor end of the trap at the other end of the tunnel whereby a pulling force exerted on the sling causes the generally tubular section of the trap to constrict more tightly about the interference screw to prevent slippage and to deter withdrawal of the trap from the tunnel.

公开(公告)号：US20180177585A1

公开(公告)日：2018-06-28

申请号：US15901425

申请日：2018-02-21

申请人： ALBERT EINSTEIN HEALTHCARE NETWORK

发明人： Minn Saing

IPC分类号： A61F2/08

CPC分类号： A61F2/0811 ,  A61F2002/0835 ,  A61F2002/0858 ,  A61F2002/0882

摘要： A connector for attaching a connective tissue to bone includes a sling for supporting and holding the connective tissue. A trap generally cooperates with the sling. The trap includes an anchor end and a sling end and a generally tubular section configured to decrease in diameter upon application of a longitudinal tensile force. The trap is dimensioned to fit within a tunnel through bone so that the connective tissue emerges from one end of the tunnel and so that an interference screw can be inserted into the tubular section at the anchor end of the trap at the other end of the tunnel whereby a pulling force exerted on the sling causes the generally tubular section of the trap to constrict more tightly about the interference screw to prevent slippage and to deter withdrawal of the trap from the tunnel.