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    METHOD, SYSTEM, AND COMPUTER PROGRAM PRODUCT FOR CALCULATING DAILY WEIGHTED AVERAGES OF GLUCOSE MEASUREMENTS (OR DERIVED QUANTITIES) WITH TIME-BASED WEIGHTS
    1.
    发明申请
    METHOD, SYSTEM, AND COMPUTER PROGRAM PRODUCT FOR CALCULATING DAILY WEIGHTED AVERAGES OF GLUCOSE MEASUREMENTS (OR DERIVED QUANTITIES) WITH TIME-BASED WEIGHTS 有权
    使用基于时间的权重计算葡萄糖测量（或衍生数量）的每日加权平均值的方法，系统和计算机程序产品

    公开(公告)号：US20120197536A1

    公开(公告)日：2012-08-02

    申请号：US13439935

    申请日：2012-04-05

    Applicant: Stefan Weinert ,  Ajay Thukral

    Inventor： Stefan Weinert ,  Ajay Thukral

    IPC: G06F19/00 ,  G01N33/66

    CPC classification number: G06F19/3406 ,  A61B5/14532 ,  C12Q1/00 ,  G06F19/00 ,  G06F19/3456 ,  G16H40/63

    Abstract: A method and system for calculating daily weighted averages of glucose measurements (or derived quantities) with time-based weights are disclosed. The present invention computes an average daily glucose value using the time based weights based on only consecutive glucose measurements in the plurality of glucose measurements with acceptable time intervals that do not exceed a predefined maximum time interval. The invention further relates to a computer program for implementing the method for calculating daily weighted averages of spot monitoring glucose measurements (or derived quantities) with the time-based weights.

    Abstract translation: 公开了一种用于计算具有时间权重的葡萄糖测量（或派生数量）的每日加权平均值的方法和系统。 本发明基于仅在不超过预定最大时间间隔的可接受的时间间隔的多个葡萄糖测量中仅连续的葡萄糖测量值，使用基于时间的权重来计算平均每日葡萄糖值。 本发明还涉及一种计算机程序，用于实现用时间权重计算点监测葡萄糖测量（或派生量）的每日加权平均值的方法。

    Method, system, and computer program product for calculating daily weighted averages of glucose measurements (or derived quantities) with time-based weights
    2.
    发明授权
    Method, system, and computer program product for calculating daily weighted averages of glucose measurements (or derived quantities) with time-based weights 有权
    方法，系统和计算机程序产品，用于计算具有时间权重的葡萄糖测量（或派生数量）的每日加权平均值

    公开(公告)号：US08175812B2

    公开(公告)日：2012-05-08

    申请号：US12215175

    申请日：2008-06-25

    Applicant: Stefan Weinert ,  Ajay Thukral

    Inventor： Stefan Weinert ,  Ajay Thukral

    IPC: G01N33/48

    CPC classification number: G06F19/3406 ,  A61B5/14532 ,  C12Q1/00 ,  G06F19/00 ,  G06F19/3456 ,  G16H40/63

    Abstract: A method and system for calculating daily weighted averages of glucose measurements (or derived quantities) with time-based weights are disclosed. The present invention computes an average daily glucose value using the time based weights based on only consecutive glucose measurements in the plurality of glucose measurements with acceptable time intervals that do not exceed a predefined maximum time interval. The invention further relates to a computer program for implementing the method for calculating daily weighted averages of spot monitoring glucose measurements (or derived quantities) with the time-based weights.

    Abstract translation: 公开了一种用于计算具有时间权重的葡萄糖测量（或派生数量）的每日加权平均值的方法和系统。 本发明基于仅在不超过预定最大时间间隔的可接受的时间间隔的多个葡萄糖测量中仅连续的葡萄糖测量值，使用基于时间的权重来计算平均每日葡萄糖值。 本发明还涉及一种计算机程序，用于实现用时间权重计算点监测葡萄糖测量（或派生量）的每日加权平均值的方法。

    SYSTEM FOR DEVELOPING PATIENT SPECIFIC THERAPIES BASED ON DYNAMIC MODELING OF PATIENT PHYSIOLOGY AND METHOD THEREOF
    3.
    发明申请
    SYSTEM FOR DEVELOPING PATIENT SPECIFIC THERAPIES BASED ON DYNAMIC MODELING OF PATIENT PHYSIOLOGY AND METHOD THEREOF 有权
    基于患者生理学动态建模的患者特异性治疗系统及其方法

    公开(公告)号：US20090006061A1

    公开(公告)日：2009-01-01

    申请号：US12119143

    申请日：2008-05-12

    Applicant: Ajay Thukral ,  Paul Galley ,  Siva Chittajallu ,  Stefan Weinert

    Inventor： Ajay Thukral ,  Paul Galley ,  Siva Chittajallu ,  Stefan Weinert

    IPC: G06G7/48

    CPC classification number: G06F19/3437 ,  A61M5/1723 ,  A61M2005/14296 ,  G06F19/00 ,  G06F19/325 ,  G06F19/3456 ,  G06F19/3468 ,  G06F19/3475 ,  G06F19/3481 ,  G06F19/36 ,  G16H10/20 ,  G16H50/20 ,  G16H50/50

    Abstract: A system for developing patient-specific therapies based on dynamic modeling of patient-specific physiology and method thereof are disclosed. The system includes software modules configured to provide access via a computer to one or more data collection protocols defining at least a type of patient-specific data to be collected and a manner in which the patient-specific data is to be collected, and to information from which one or more patient-specific models, configured to simulate one or more aspects of the patient's physiology, is developed. Another software module of the system is configured to provide access via the computer to one or more software tools that apply patient-specific data, collected according to the one or more data collection protocols, to the one or more patient specific models to determine therefrom one or more patient-specific therapies.

    Abstract translation: 公开了一种基于患者特异性生理学的动态建模及其方法开发患者特异性疗法的系统。 该系统包括软件模块，被配置为经由计算机向一个或多个数据收集协议提供访问，所述数据收集协议至少定义了要收集的患者特定数据类型，以及要收集患者特定数据的方式以及信息 开发了用于模拟患者生理学的一个或多个方面的一个或多个患者特异性模型。 该系统的另一个软件模块被配置为经由计算机向一个或多个软件工具提供访问，该软件工具将根据一个或多个数据收集协议收集的患者特定数据应用于一个或多个患者特定模型，从而确定一个 或更多的患者特异性疗法。

    System and method providing for user intervention in a diabetes control arrangement
    4.
    发明申请
    System and method providing for user intervention in a diabetes control arrangement 审中-公开
    提供糖尿病控制安排中的用户干预的系统和方法

    公开(公告)号：US20060276771A1

    公开(公告)日：2006-12-07

    申请号：US11145910

    申请日：2005-06-06

    Applicant: Paul Galley ,  Ajay Thukral ,  Siva Chittajallu ,  Robin Wagner ,  Stefan Weinert ,  Steven Bousamra

    Inventor： Paul Galley ,  Ajay Thukral ,  Siva Chittajallu ,  Robin Wagner ,  Stefan Weinert ,  Steven Bousamra

    IPC: A61M31/00

    CPC classification number: A61M5/172 ,  A61M5/1723 ,  A61M2005/14208 ,  A61M2005/14296 ,  A61M2205/3569 ,  A61M2230/201 ,  G06F19/3468 ,  G16H50/50

    Abstract: A system providing for user intervention in a medical control arrangement may comprise a first user intervention mechanism responsive to user selection thereof to produce a first user intervention signal, a second user intervention mechanism responsive to user selection thereof to produce a second user intervention signal, and a processor executing a drug delivery algorithm forming part of the medical control arrangement. The processor may be responsive to the first user intervention signal to include an intervention therapy value in the execution of the drug delivery algorithm, and responsive to the second user intervention signal to exclude the intervention therapy value from the execution of the drug delivery algorithm. The medical control arrangement may be a diabetes control arrangement, the drug delivery algorithm may be an insulin delivery algorithm, and the intervention therapy value may be, for example, an intervention insulin quantity or an intervention carbohydrate quantity.

    Abstract translation: 提供用户干预医疗控制装置的系统可以包括响应于用户选择其以产生第一用户干预信号的第一用户干预机制，响应于用户选择以产生第二用户干预信号的第二用户干预机制，以及 执行形成医疗控制装置的一部分的药物递送算法的处理器。 所述处理器可以响应于所述第一用户干预信号，以在所述药物递送算法的执行中包括干预治疗值，并且响应于所述第二用户干预信号排除所述介入治疗值与所述药物递送算法的执行。 医疗控制装置可以是糖尿病控制装置，药物递送算法可以是胰岛素递送算法，并且干预治疗值可以是例如干预胰岛素量或干预碳水化合物量。

    Diabetes management system
    5.
    发明授权
    Diabetes management system 有权
    糖尿病管理系统

    公开(公告)号：US06544212B2

    公开(公告)日：2003-04-08

    申请号：US09918623

    申请日：2001-07-31

    Applicant: Paul J. Galley ,  Ajay Thukral ,  Siva K. Chittajallu ,  Stefan Weinert

    Inventor： Paul J. Galley ,  Ajay Thukral ,  Siva K. Chittajallu ,  Stefan Weinert

    IPC: A61M100

    CPC classification number: A61B5/14532 ,  A61B5/7275 ,  G06F19/00 ,  G06F19/3456

    Abstract: A system is provided that enables glycemic control for a subject. The system includes an insulin delivery unit, a glucose sensor, and a control unit. The control unit includes a processor unit that receives glucose value readings from the glucose sensor, executes an algorithm that predicts a glucose value at a predetermined time in the future, compares that predicted glucose value to a pre-determined glucose value range, and determines a corrective amount of insulin to be administered when the predictive glucose value lies outside of the predetermined glucose value range. The control unit also includes a communication unit that transmits the corrective amount to the delivery unit.

    Abstract translation: 提供了能够使受试者进行血糖控制的系统。 该系统包括胰岛素输送单元，葡萄糖传感器和控制单元。 控制单元包括处理器单元，其从葡萄糖传感器接收葡萄糖值读数，执行在将来的预定时间预测葡萄糖值的算法，将该预测葡萄糖值与预定葡萄糖值范围进行比较，并确定 当预测葡萄糖值处于预定葡萄糖值范围之外时要施用的胰岛素的校正量。 控制单元还包括将校正量发送到传送单元的通信单元。

    Method and system for calculating daily weighted averages of glucose measurements (or derived quantities) with time based-weights
    6.
    发明授权
    Method and system for calculating daily weighted averages of glucose measurements (or derived quantities) with time based-weights 有权
    用时间基准权重计算葡萄糖测量（或派生数量）的每日加权平均值的方法和系统

    公开(公告)号：US09092553B2

    公开(公告)日：2015-07-28

    申请号：US13439935

    申请日：2012-04-05

    Applicant: Stefan Weinert ,  Ajay Thukral

    Inventor： Stefan Weinert ,  Ajay Thukral

    IPC: C12Q1/00 ,  G06F19/00 ,  A61B5/145

    CPC classification number: G06F19/3406 ,  A61B5/14532 ,  C12Q1/00 ,  G06F19/00 ,  G06F19/3456 ,  G16H40/63

    Abstract: A method and system for calculating daily weighted averages of glucose measurements (or derived quantities) with time-based weights are disclosed. The present invention computes an average daily glucose value using the time based weights based on only consecutive glucose measurements in the plurality of glucose measurements with acceptable time intervals that do not exceed a predefined maximum time interval. The invention further relates to a computer program for implementing the method for calculating daily weighted averages of spot monitoring glucose measurements (or derived quantities) with the time-based weights.

    Abstract translation: 公开了一种用于计算具有时间权重的葡萄糖测量（或派生数量）的每日加权平均值的方法和系统。 本发明基于仅在不超过预定最大时间间隔的可接受的时间间隔的多个葡萄糖测量中仅连续的葡萄糖测量值，使用基于时间的权重来计算平均每日葡萄糖值。 本发明还涉及一种计算机程序，用于实现用时间权重计算点监测葡萄糖测量（或派生量）的每日加权平均值的方法。

    System for developing patient specific therapies based on dynamic modeling of patient physiology and method thereof
    7.
    发明授权
    System for developing patient specific therapies based on dynamic modeling of patient physiology and method thereof 有权
    基于患者生理学动态建模及其方法开发患者特异性疗法的系统

    公开(公告)号：US08818782B2

    公开(公告)日：2014-08-26

    申请号：US12119143

    申请日：2008-05-12

    Applicant: Ajay Thukral ,  Paul Galley ,  Siva Chittajallu ,  Stefan Weinert

    Inventor： Ajay Thukral ,  Paul Galley ,  Siva Chittajallu ,  Stefan Weinert

    IPC: G06F19/00

    CPC classification number: G06F19/3437 ,  A61M5/1723 ,  A61M2005/14296 ,  G06F19/00 ,  G06F19/325 ,  G06F19/3456 ,  G06F19/3468 ,  G06F19/3475 ,  G06F19/3481 ,  G06F19/36 ,  G16H10/20 ,  G16H50/20 ,  G16H50/50

    Abstract: A system for developing patient-specific therapies based on dynamic modeling of patient-specific physiology and method thereof are disclosed. The system includes software modules configured to provide access via a computer to one or more data collection protocols defining at least a type of patient-specific data to be collected and a manner in which the patient-specific data is to be collected, and to information from which one or more patient-specific models, configured to simulate one or more aspects of the patient's physiology, is developed. Another software module of the system is configured to provide access via the computer to one or more software tools that apply patient-specific data, collected according to the one or more data collection protocols, to the one or more patient specific models to determine therefrom one or more patient-specific therapies.

    Abstract translation: 公开了一种基于患者特异性生理学的动态建模及其方法开发患者特异性疗法的系统。 该系统包括软件模块，被配置为经由计算机向一个或多个数据收集协议提供访问，所述数据收集协议至少定义了要收集的患者特定数据类型，以及要收集患者特定数据的方式以及信息 开发了用于模拟患者生理学的一个或多个方面的一个或多个患者特异性模型。 该系统的另一软件模块被配置为经由计算机向一个或多个软件工具提供访问，该软件工具将根据一个或多个数据收集协议收集的患者特定数据应用于一个或多个患者特定模型，从而确定一个 或更多的患者特异性疗法。

    Medical diagnosis, therapy, and prognosis system for invoked events and methods thereof
    8.
    发明授权
    Medical diagnosis, therapy, and prognosis system for invoked events and methods thereof 有权
    用于调用事件的医学诊断，治疗和预后系统及其方法

    公开(公告)号：US08712748B2

    公开(公告)日：2014-04-29

    申请号：US12119201

    申请日：2008-05-12

    Applicant: Ajay Thukral ,  Paul Galley ,  Siva Chittajallu ,  Stefan Weinert

    Inventor： Ajay Thukral ,  Paul Galley ,  Siva Chittajallu ,  Stefan Weinert

    IPC: G06F19/00

    CPC classification number: G16H50/50 ,  G06F19/00 ,  G06F19/3456 ,  G06Q50/22 ,  G16H50/20

    Abstract: A diagnosis, therapy and prognosis system (DTPS) and method thereof to help either the healthcare provider or the patient in diagnosing, treating and interpreting data are disclosed. The apparatus provides data collection based on protocols, and mechanism for testing data integrity and accuracy. The data is then driven through an analysis engine to characterize in a quantitative sense the metabolic state of the patient's body. The characterization is then used in diagnosing the patient, determining therapy, evaluating algorithm strategies and offering prognosis of potential use case scenarios.

    Abstract translation: 公开了诊断，治疗和预后系统（DTPS）及其方法，以帮助医务人员或患者诊断，治疗和解释数据。 该设备提供基于协议的数据收集，以及测试数据完整性和准确性的机制。 然后通过分析引擎驱动数据，以定量的方式表征患者身体的代谢状态。 然后将该特征用于诊断患者，确定治疗，评估算法策略并提供潜在用例情景的预后。

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