-
公开(公告)号:US10308611B2
公开(公告)日:2019-06-04
申请号:US15741722
申请日:2016-03-18
Applicant: AUROBINDO PHARMA LTD
Inventor: Sukumar Nandi , Akkina Naresh , Syam Prasad Reddy Rao Annareddy , Gona Bala Narsimha Reddy , Meenakshi Sunderam Sivakumaran
IPC: C07D223/16
Abstract: The present invention provides a process for the preparation of crystalline Lorcaserin hydrochloride hemihydrate of Formula (Ia), which comprises, Formula (Ia) (i) providing a solution of Lorcaserin base in a solvent; (ii) if water is present, removing water from the reaction mixture; (iii) adding hydrogen chloride to the reaction mixture; (iv) combining the reaction mixture with a suitable anti-solvent; and (v) isolating the crystalline Lorcaserin hydrochloride hemihydrate of Formula (Ia).
-
2.
公开(公告)号:US20190070120A1
公开(公告)日:2019-03-07
申请号:US16083534
申请日:2017-03-09
Applicant: Aurobindo Pharma Ltd.
IPC: A61K9/20 , A61K9/28 , A61K31/7042 , A61P3/04 , A61P3/10
Abstract: The present invention relates to a binder tree pharmaceutical composition comprising canagliflozin or a prodrug or a pharmaceutically acceptable salt thereof, and one or more 5 pharmaceutically acceptable excipients, wherein the said composition is devoid of canagliflozin hemihydrate, and having acceptable chemical stability, polymorphic stability & comparative dissolution and bioequivalence profile to that of INVOKANA® tablets.
-
公开(公告)号:US20190023706A1
公开(公告)日:2019-01-24
申请号:US16081944
申请日:2017-02-24
Applicant: Sandeep JAIN , Komel ANSARI , Subramanyam MADDALA , Sivakumaran MEENAKSHISUNDERAM , AUROBINDO PHARMA LTD
Inventor: Sandeep Jain , Komel Ansari , Subramanyam Maddala , Sivakumaran Meenakshisundaram
IPC: C07D473/18
Abstract: The present invention relates to an improved process for the preparation of Valacyclovir or pharmaceutically acceptable salts thereof, which comprises reaction of amine-protected Valacyclovir or its salt with deprotecting agent in a continuous flow reactor.
-
公开(公告)号:US12221440B2
公开(公告)日:2025-02-11
申请号:US17427633
申请日:2020-02-06
Applicant: Aurobindo Pharma Ltd.
Inventor: Gangadhara Bhima Shankar Nangi , Ramadas Chavakula , Venkata Rama Krishna Murthy Moturu , Jyothi Sudharshan Chakradhar Saladi , Sandeep Kumar Vadla , Sadashiv Jagtap , Sivakumaran Meenakshisunderam
IPC: C07D471/04 , A61K31/519
Abstract: The present invention relates to a process for the preparation of Trametinib acetic acid solvate (Ia): The present invention also directed towards a pharmaceutical composition comprising Trametinib acetic acid solvate (Ia) and optionally one or more pharmaceutically acceptable excipients or carriers.
-
5.
公开(公告)号:US20230248667A1
公开(公告)日:2023-08-10
申请号:US18105795
申请日:2023-02-03
Applicant: Aurobindo Pharma Ltd
Inventor: Soumyajit Behera , Satheesh Kumar Gajjala , Nilesh Bhandari , Nagaprasad Vishnubhotla , Sivakumaran Meenakshisunderam
IPC: A61K31/137 , A61K31/495 , A61K9/28
CPC classification number: A61K31/137 , A61K31/495 , A61K9/2893 , A61K9/2866 , A61K9/282
Abstract: This invention relates to dosage forms comprising pseudoephedrine or a salt thereof, for extended-release up to 24 hours, and process of making such dosage forms. This invention provides a non-osmotic extended-release dosage form comprising pseudoephedrine hydrochloride which can be administered to patients who need and/or desire a decongestant medication up to 24 hours. This invention also relates to dosage forms comprising pseudoephedrine or a salt thereof and cetirizine or levocetirizine or its salts thereof for extended-release up to 24 hours, and process of making such dosage forms.
-
6.
公开(公告)号:US20210177822A1
公开(公告)日:2021-06-17
申请号:US17119250
申请日:2020-12-11
Applicant: Aurobindo Pharma Ltd.
Inventor: Saravanan Kannusamy , Prabhakaran Chakkirala , Rakesh Sarkar , Sivakumaran Meenakshisunderam
IPC: A61K31/4468 , A61K9/48 , A61K9/00
Abstract: The present invention relates to prepare pharmaceutical compositions comprising pimavanserin or a pharmaceutically acceptable salt thereof, processes for manufacturing said pharmaceutical compositions comprising pimavanserin or a pharmaceutically acceptable salt thereof. Also pharmaceutical compositions comprising pimavanserin or a pharmaceutically acceptable salt thereof for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis.
-
公开(公告)号:US20180008547A1
公开(公告)日:2018-01-11
申请号:US15548063
申请日:2016-02-01
Applicant: Shridhar INAGANTI , Venugopala CHOKKASANDRA JAYARAMA REDDY , Jayant KARAJGI , Sivakumaran MEENAKSHISUNDERAM , AUROBINDO PHARMA LTD
Inventor: Shridhar Inaganti , Venugopala Chokkasandra Jayarama Reddy , Jayant Karajgi , Sivakumaran Meenakshisunderam
CPC classification number: A61K9/4808 , A61K9/485 , A61K9/4858 , A61K9/4866 , A61K38/10
Abstract: The present invention relates to stable oral composition comprising linaclotide or its pharmaceutically acceptable salts, complexes, polymorphs, hydrates, solvates, enantiomers or racemates, process of preparation thereof and methods of using the same.
-
8.
公开(公告)号:US11648242B2
公开(公告)日:2023-05-16
申请号:US17119250
申请日:2020-12-11
Applicant: Aurobindo Pharma Ltd.
Inventor: Saravanan Kannusamy , Prabhakaran Chakkirala , Rakesh Sarkar , Sivakumaran Meenakshisunderam
IPC: A61K31/4468 , A61K9/48 , A61K9/00
CPC classification number: A61K31/4468 , A61K9/0053 , A61K9/485 , A61K9/4833 , A61K9/4858 , A61K9/4866
Abstract: The present invention relates to prepare pharmaceutical compositions comprising pimavanserin or a pharmaceutically acceptable salt thereof, processes for manufacturing said pharmaceutical compositions comprising pimavanserin or a pharmaceutically acceptable salt thereof. Also pharmaceutical compositions comprising pimavanserin or a pharmaceutically acceptable salt thereof for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis.
-
公开(公告)号:US20200253955A1
公开(公告)日:2020-08-13
申请号:US16462856
申请日:2017-11-22
Applicant: Aurobindo Pharma Ltd
Inventor: Rama Shankar , Nimesh Chandra Misra , Siva Rama Kasibabu Velegula , Suresh Chapala , Sivakumaran Meenakshisunderam
IPC: A61K31/485
Abstract: The present invention relates to solid dispersion of Naloxegol oxalate. Further, the present invention relates to an improved process for Naloxegol oxalate and intermediates thereof.
-
公开(公告)号:US20180194743A1
公开(公告)日:2018-07-12
申请号:US15741859
申请日:2016-05-09
Applicant: Sukumar NANDI , Shantan Kumar REDDY , Gona BALANARASHIMHA REDDY , AUROBINDO PHARMA LTD
Inventor: Sukumar Nandi , Shantan Kumar Reddy , Gona Bala Narashimha Reddy , Sivakumaran Meenakshisundaram
IPC: C07D277/40
CPC classification number: C07D277/40
Abstract: The present invention provides a process for the preparation of α-Form crystals of Mirabegron using a solvent selected from water.
-
-
-
-
-
-
-
-
-