知搜-全球专利检索

  1. 登录
  2. 注册

搜索结果

92 条记录 (耗时 0.026 秒)

    Systems and methods for managing large medical image data
    1.
    发明授权
    Systems and methods for managing large medical image data 有权

    公开(公告)号：US12027251B2

    公开(公告)日：2024-07-02

    申请号：US15436180

    申请日：2017-02-17

    申请人： Agfa HealthCare NV

    发明人： Viktor Kopylov

    IPC分类号： G16H30/20 ,  H04L67/568

    CPC分类号： G16H30/20 ,  H04L67/568

    摘要： A system and method for managing medical image data items. A large image manager is used to store medical image data items external to a core PACS. Representative objects are generated and provided to the PACS to be incorporated into the core PACS workflows. The representative objects can be generated by extracted pixel data and metadata from the medical image data items. The representative objects are generated in a format compatible with the protocol used by the PACS workflows. Requests sent to the PACS for medical images can be re-routed to the large image manager to provide the requested images.

    Geometric misalignment correction method for chest tomosynthesis reconstruction
    3.
    发明授权
    Geometric misalignment correction method for chest tomosynthesis reconstruction 有权

    公开(公告)号：US10945682B2

    公开(公告)日：2021-03-16

    申请号：US16308303

    申请日：2017-06-08

    申请人： Agfa Healthcare NV

    发明人： Jeroen Cant ,  Jan Sijbers

    IPC分类号： A61B6/02 ,  A61B6/00 ,  G06T11/00 ,  G16H30/40

    摘要： A method and system to correct for alignment errors between assumed and actual geometric parameters of an acquisition geometry during image reconstruction in a chest tomosynthesis application includes receiving at least 2 raw projection images acquired on at least 2 different positions in a known acquisition geometry, determining an actual geometric parameter value by determining the minimum of a redundant planes cost function which is calculated for a varying range of the geometric parameter values, and which is determined by: a) at least one plane which intersects an X-ray source trajectory with at least two points, b) an intersection between the planes and a detector surface for which points the source positions are determined, and c) for which the parameters determining the intersection (λ, μ, l) are used for the construction of the cost function, applying the calculated actual geometric parameter value of the acquisition geometry for the image reconstruction of the plurality of images, characterized in that, a weighting function is applied to the plurality of acquired images prior to calculating the cost function.

    Method for determining the short axis in a lesion region in a three dimensional medical image
    5.
    发明授权
    Method for determining the short axis in a lesion region in a three dimensional medical image 有权

    公开(公告)号：US10127683B2

    公开(公告)日：2018-11-13

    申请号：US15541027

    申请日：2015-12-16

    申请人： Agfa HealthCare NV

    发明人： Asma Ouji ,  Yoni De Witte

    IPC分类号： G06T7/62 ,  G06T7/00

    摘要： A short axis in a 3 dimensional image of a lesion is determined starting from voxels defining the long axis and voxels in the plane of the long axis. Voxels within the plane of the long axis are projected perpendicularly onto the long axis and receive an identifier indicative of the region on the long axis onto which they are projected. Distances between points (projected sub-voxels) in pairs of points within the same range and within adjacent ranges are evaluated in order to determine the longest distance.

    PROCESS FOR PURIFYING 1,4,7,10-TETRA-AZACYCLODODECANE-1,4,7,10-TETRAACETIC ACID
    9.
    发明申请
    PROCESS FOR PURIFYING 1,4,7,10-TETRA-AZACYCLODODECANE-1,4,7,10-TETRAACETIC ACID 审中-公开
    净化1,4,7,10-四氮杂环十二烷基-1,4,7,10-四氢酸的方法

    公开(公告)号：US20170007726A1

    公开(公告)日：2017-01-12

    申请号：US15116263

    申请日：2015-02-02

    申请人： Agfa HealthCare NV

    发明人： Diederik BUFFEL ,  Xavier BOI ,  Judith PYPE

    IPC分类号： A61K49/10 ,  B01D61/02 ,  A61K47/18 ,  C07D295/15 ,  C07F5/00

    CPC分类号： A61K49/108 ,  A61K47/18 ,  B01D61/027 ,  B01D2311/2649 ,  B01D2311/2673 ,  B01D2315/16 ,  C07D257/02 ,  C07D295/15 ,  C07F5/003

    摘要： A process for purifying a compound of formula 1, includes the following steps: a) adding an acid to an aqueous solution of the compound of formula 1, including salts and hydrates thereof so as to obtain a slurry having a pH≦3; and b) filtering the slurry and at least one time washing the obtained precipitate with a liquid comprising water; and c) dissolving the precipitate obtained in step b) in water to obtain an aqueous solution; and d) filtering of the solution obtained in step c) over a nanofiltration membrane having a Molecular Weight Cut Off in the range from 150 to 500 and wherein optionally, between step c) and step d) the pH of the aqueous solution is adjusted to a pH value in the pH range as specified by the manufacturer of the nanofiltration membrane. A process for preparing a gadolinium complex of the purified compound of formula 1 is also disclosed. This gadolinium complex can be used for making a pharmaceutical composition as a contrast agent for magnetic resonance imaging.

    摘要翻译： 包括以下步骤：a）向式1化合物的水溶液中加入酸，包括其盐和水合物，以获得pH≤3的浆料; 和b）过滤浆料，并至少一次用包含水的液体洗涤所获得的沉淀物; 和c）将步骤b）中获得的沉淀溶解在水中以获得水溶液; 以及d）将步骤c）中获得的溶液过滤到分子量截留在150-500范围内的纳滤膜中，并且其中任选地在步骤c）和步骤d）之间，将水溶液的pH调节至 在纳米过滤膜制造商规定的pH范围内的pH值。 还公开了制备纯化的式1化合物的钆络合物的方法。 该钆络合物可用于制备用作磁共振成像的造影剂的药物组合物。