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公开(公告)号：US08109996B2
公开(公告)日：2012-02-07
申请号：US11066346
申请日：2005-02-25
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2250/0039
摘要： A cardiac-valve prosthesis is adapted for percutaneous implantation. The prosthesis includes an armature adapted for deployment in a radially expanded implantation position, the armature including a support portion and an anchor portion, which are substantially axially coextensive with respect to one another. A set of leaflets is coupled to the support portion. The leaflets can be deployed with the armature in the implantation position. The leaflets define, in the implantation position, a flow duct that is selectably obstructable. The anchor portion can be deployed to enable anchorage of the cardiac-valve prosthesis at an implantation site.
摘要翻译： 心脏瓣膜假体适用于经皮植入。 假体包括适于展开在径向扩张的植入位置的电枢，所述电枢包括支撑部分和锚定部分，所述支撑部分和锚定部分彼此基本轴向共延伸。 一组传单联接到支撑部分。 传单可以在植入位置上与衔铁一起展开。 在植入位置中，传单限定了可选择地阻塞的流动管道。 锚固部分可以被部署以使得能够在植入部位处锚定心脏瓣膜假体。
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公开(公告)号：US08103360B2
公开(公告)日：2012-01-24
申请号：US12411681
申请日：2009-03-26
申请人： Arthur J. Foster
发明人： Arthur J. Foster
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61B5/0422 , A61B2562/222 , A61N1/056 , A61N1/086
摘要： Medical electrical leads equipped with spacer elements and configured for use during medical procedures such as magnetic resonance imaging (MRI) are disclosed. An illustrative medical electrical lead includes a proximal connector, an insulated lead body including at least one electrode, a helically coiled conductor wire, and a helically coiled spacer element interstitially disposed between adjacent turns of the conductor wire.
摘要翻译： 公开了配备有间隔元件并配置用于诸如磁共振成像（MRI）的医疗过程期间使用的医用电气引线。 示例性的医用电线包括近端连接器，绝缘引线主体，其包括至少一个电极，螺旋线圈导体线，以及间隙地布置在导体线的相邻匝之间的螺旋线圈间隔元件。
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公开(公告)号：US08100531B2
公开(公告)日：2012-01-24
申请号：US12307677
申请日：2007-07-09
摘要： An opthalmoscope for examining a patient's eye includes an illumination device for generating an illumination beam Illumination imaging optics image the illumination beam onto the eye and a scanning device scans the illumination beam over the eye. The opthalmoscope also includes an observation device and observation imaging optics for imaging an observation beam generated by reflection of the illumination beam from the eye onto the observation device. An electronic shutter excludes stray light from the observation beam. The observation device comprises an electronic sensor with an array of photosensitive pixels that can respectively be activated and/or read out in rows, and the scanning device includes an electronic drive circuit for reading out at least one pixel row of the sensor.
摘要翻译： 用于检查患者眼睛的眼镜包括用于产生照明光束照明成像光学器件的照明装置，将照明光束图像到眼睛上，扫描装置扫描眼睛上的照明光束。 眼镜还包括观察装置和观察成像光学元件，用于对从眼睛的照射光束反射到观察装置上产生的观察光束进行成像。 电子快门不包括来自观察光束的杂散光。 观察装置包括具有分别能够被行和/或读出的感光像素阵列的电子传感器，扫描装置包括用于读出传感器的至少一个象素行的电子驱动电路。
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4.发明授权公开(公告)号：US08086321B2
公开(公告)日：2011-12-27
申请号：US12329399
申请日：2008-12-05
申请人： Masoud Ameri
发明人： Masoud Ameri
IPC分类号： A61N1/16
CPC分类号： A61N1/056 , A61N1/086 , A61N1/3718
摘要： A medical device includes a pulse generator and an electrode configured to contact tissue in a body vessel. The medical device includes a lead that includes a lead connector. The lead connector connects a pulse generator with an electrode via a conductive path. An electrode switch is electrically connected between the lead conductor and the electrode. The electrode switch includes an open state preventing the conductive path between the lead and the electrode. The electrode switch includes a closed state establishing the conductive path between the lead and the electrode when a voltage is applied across the electrode switch that exceeds a threshold voltage. The electrode switch in the open state electrically shields the electrode from electromagnetic radiation and induced voltages during magnetic resonance imaging.
摘要翻译： 医疗装置包括脉冲发生器和构造成接触身体血管中的组织的电极。 医疗装置包括引线，其包括引线连接器。 引线连接器通过导电路径将脉冲发生器与电极连接。 电极开关电连接在引线导体和电极之间。 电极开关包括阻止引线和电极之间的导电路径的开放状态。 当跨越电极开关的电压超过阈值电压时，电极开关包括建立在引线和电极之间的导电路径的关闭状态。 处于断开状态的电极开关在磁共振成像期间电屏蔽电磁辐射和感应电压。
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公开(公告)号：US08082915B2
公开(公告)日：2011-12-27
申请号：US12414475
申请日：2009-03-30
IPC分类号： F23B13/04
CPC分类号： F24B1/024 , F23H15/00 , F23M2900/13003 , F23N5/00 , F23N5/203 , F23N2039/02 , F24B1/026 , F24B1/028 , F24B1/195 , F24B7/025
摘要： According to embodiments of the present invention, a pellet stove includes a firepot assembly with a bottom plate slideable along rails to move between a closed position during combustion in the firepot and an open position during ash removal. According to other embodiments, a firebox or combustion enclosure includes a plurality of airfoils formed on the inner and outer surfaces of the enclosure to facilitate heat exchange between exhaust gases flowing across the inner surface of the enclosure and air blown across the outer surface of the enclosure. According to some embodiments, the airfoils and enclosure are of integral unibody construction. According to yet other embodiments, a user sets parameters via a wall control unit, and a stove control unit receives the parameters and automatically controls fuel feed rate, ignition, convection blower, combustion blower, and/or firepot cleaning based on the one or more parameters.
摘要翻译： 根据本发明的实施例，颗粒炉包括一个具有底板的火锅组件，该底板可沿轨道滑动，以便在烟火中燃烧期间的关闭位置和除灰期间的打开位置之间移动。 根据其他实施例，火箱或燃烧外壳包括形成在外壳的内表面和外表面上的多个翼型件，以促进流过外壳内表面的废气和穿过外壳外表面的空气之间的热交换 。 根据一些实施例，翼型件和外壳是整体的一体结构。 根据其他实施例，用户经由墙壁控制单元设置参数，并且炉控制单元接收参数并基于一个或多个自动控制燃料供给速率，点火，对流鼓风机，燃烧鼓风机和/或火锅清洁 参数。
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公开(公告)号：US08071551B2
公开(公告)日：2011-12-06
申请号：US12051373
申请日：2008-03-19
申请人： Leland Shapiro
发明人： Leland Shapiro
CPC分类号： A61K38/57 , Y02A50/414
摘要： The instant invention provides a method of treating an animal suffering a disease characterized by excessive apoptosis by administering a therapeutically effective amount of at least one serine protease inhibitor and thereafter monitoring a decrease in apoptosis. The inhibitor of the invention includes α1-antitrypsin or an α1-antitrypsin-like agent, including, but not limited to oxidation-resistant variants of α1-antitrypsin, and peptoids with antitrypsin activity. The diseases treatable by the invention include cancer, autoimmune disease, sepsis neurodegenerative disease, myocardial infarction, stroke, ischemia-reperfusion injury, toxin induced liver injury and AIDS. The method of the invention is also suitable for the prevention or amelioration of diseases characterized by excessive apoptosis.
摘要翻译： 本发明提供一种通过施用治疗有效量的至少一种丝氨酸蛋白酶抑制剂来治疗特征为过度凋亡的疾病的动物的方法，然后监测凋亡的降低。 本发明的抑制剂包括α1-抗胰蛋白酶或α1-抗胰蛋白酶样试剂，包括但不限于α1-抗胰蛋白酶的抗氧化变体和具有抗胰蛋白酶活性的拟肽。 本发明可治疗的疾病包括癌症，自身免疫疾病，败血症神经退行性疾病，心肌梗塞，中风，缺血再灌注损伤，毒素诱导的肝损伤和艾滋病。 本发明的方法也适用于预防或改善以过度凋亡为特征的疾病。
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公开(公告)号：US08061778B2
公开(公告)日：2011-11-22
申请号：US12048111
申请日：2008-03-13
申请人： Jay R. Machael , Jesse Hahn , John Robert Koch , Todd Ireland , Brett Kooistra
发明人： Jay R. Machael , Jesse Hahn , John Robert Koch , Todd Ireland , Brett Kooistra
CPC分类号： A47C1/03
摘要： A chair arm adjustment device according to embodiments of the present invention includes an arm pad base slidably coupled to the arm support, the arm pad base sliding substantially horizontally in two degrees of freedom with respect to the arm support within a range of motion of the arm pad base with respect to the arm support, and an arm brake assembly coupled with the arm pad base, the arm brake assembly moveable between a locked position in which the arm brake assembly substantially inhibits movement of the arm pad base relative to the arm support and an unlocked position in which the arm brake assembly does not substantially inhibit movement of the arm pad base relative to the arm support, wherein the arm brake assembly moves from the unlocked position to the locked position at any position of the arm pad base within the range of motion.
摘要翻译： 根据本发明的实施例的椅子臂调节装置包括可滑动地联接到臂支撑件的臂垫基座，臂垫基座在臂的运动范围内相对于臂支撑件基本上水平地在两个自由度上滑动 垫臂基座相对于臂支撑件和臂式制动器组件，其与臂垫基座联接，所述臂制动器组件可在锁定位置之间移动，在所述锁定位置中，所述臂制动器组件基本上禁止所述臂垫基座相对于所述臂支撑件的运动; 其中所述臂制动器组件基本上不阻止所述臂垫基座相对于所述臂支撑件的运动的解锁位置，其中所述臂制动器组件在所述臂垫基座的任何位置在所述范围内从所述解锁位置移动到所述锁定位置 的运动。
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8.发明授权公开(公告)号：US08055354B2
公开(公告)日：2011-11-08
申请号：US12467978
申请日：2009-05-18
申请人： Paul E. Zarembo , Mohan Krishnan , David Durand
发明人： Paul E. Zarembo , Mohan Krishnan , David Durand
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , H01R13/18 , H01R2201/12 , Y10T29/49117
摘要： An implantable lead comprises a lead body extending from a lead proximal end portion to a lead distal end portion. The lead body includes one or more longitudinally extending lumens. A conductor is received in, and extends along, a lumen. In varying examples, the implantable lead further comprises a tubular electrode co-axial with, and overlying portions of, the lead body. In one example, a lumen wall is sized and shaped to urge an electrically conductive interposer coupled with the conductor toward an inner surface of the electrode. In another example, a ring member is disposed within a lumen and the conductor is drawn and coupled thereto. In yet another example, an electrically conductive connector couples a first and a second conductor via grooves or threads. In a further example, an axial support member couples a distal end electrode and the lead body. Methods associated with the foregoing are also discussed.
摘要翻译： 可植入引线包括从引线近端部分延伸到引线远端部分的引线体。 引线体包括一个或多个纵向延伸的腔。 导体被容纳在内腔中并沿着其延伸。 在可变示例中，可植入引线还包括与引线主体同轴并且覆盖引线主体的部分的管状电极。 在一个示例中，腔壁的尺寸和形状被设计成将与导体耦合的导电插入件推向电极的内表面。 在另一示例中，环构件设置在管腔内并且导体被拉伸并与其连接。 在又一示例中，导电连接器通过凹槽或螺纹将第一和第二导体连接。 在另一示例中，轴向支撑构件将远端电极和引线体联接。 还讨论了与前述相关的方法。
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公开(公告)号：US08052731B2
公开(公告)日：2011-11-08
申请号：US11422000
申请日：2006-06-02
CPC分类号： A61N1/057 , A61B18/1492 , A61B2017/00243
摘要： A medical electrical lead adapted to be at least partially implanted in a cardiac vessel includes a fixation feature operable to change from an undeployed configuration to a deployed configuration in which the fixation feature is adapted to engage an inner surface of the cardiac vessel. A tendon is disposed within a lumen of the lead and is operatively connected to the fixation feature and adapted to cause the fixation feature to change from the undeployed configuration to the deployed configuration for acute and/or chronic fixation of the lead. In one embodiment, the fixation feature includes a deflectable region of the lead which in the deployed configuration causes a surface of the lead body to engage the inner surface of the cardiac vessel. In another embodiment, the fixation feature includes a radially expandable structure for engaging the inner surface of the vessel in the deployed configuration.
摘要翻译： 适于至少部分地植入心脏血管的医用电线包括固定特征，其可操作以从未部署的构型改变为展开构造，其中固定特征适于接合心脏血管的内表面。 腱设置在引导件的内腔中并且可操作地连接到固定特征并且适于使固定特征从未部署的构型改变为用于引导的急性和/或慢性固定的展开配置。 在一个实施例中，固定特征包括引线的可偏转区域，其在展开构型中引起引线主体的表面接合心脏血管的内表面。 在另一个实施例中，固定特征包括用于在展开构型中接合容器内表面的径向可扩展结构。
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公开(公告)号：US08051553B1
公开(公告)日：2011-11-08
申请号：US11956628
申请日：2007-12-14
CPC分类号： G11B5/4826 , Y10T29/49021 , Y10T29/49032 , Y10T29/49041 , Y10T29/5313 , Y10T29/53165
摘要： Apparatus for adjusting the static attitude of a head suspension having a gimbal with at least one gimbal arm. One embodiment of the invention includes a pair of first contacting members contacting a first side of the gimbal arm at a pair of spaced apart locations, and a second contacting member contacting a second side of the gimbal arm at an intermediate location between the spaced apart locations. The first and second contacting members move together relative to each other, plastically deforming the gimbal arm by the relative movement between the second and first contacting members while the spaced apart location between the first contacting members is maintained during the plastic deformation such that at least one of a pitch and roll parameter of the gimbal is adjusted to a desired amount.
摘要翻译： 用于调节具有至少一个万向臂的万向架的头部悬架的静态姿态的装置。 本发明的一个实施例包括一对第一接触构件，其在一对间隔开的位置处接触万向臂的第一侧，并且第二接触构件在万向架臂的第二侧处于间隔开的位置 。 第一和第二接触构件相对于彼此一起移动，通过第二和第一接触构件之间的相对运动使万向臂臂塑性变形，同时在塑性变形期间保持第一接触构件之间的间隔开的位置，使得至少一个 的万向节的俯仰和滚动参数被调节到期望的量。
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