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公开(公告)号：US12121440B2
公开(公告)日：2024-10-22
申请号：US17849031
申请日：2022-06-24
申请人： SECADA MEDICAL LLC
发明人： Russell Cook
CPC分类号： A61F2/2846 , A61F2002/2835 , A61F2002/30062 , A61F2310/00179 , A61F2310/00359 , A61F2310/00371
摘要： The present invention relates to methods for bioresorbable and biodegradable casings having both micropores and macropores for providing shape, structure and containment to different bone grafting materials. Kits and methods of use are also described.
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![Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl] piperazin-1-yl]ethyl pyridine-3-carboxylate](/abs-image/US/2024/10/08/US12110275B2/abs.jpg.150x150.jpg)
公开(公告)号：US12110275B2
公开(公告)日：2024-10-08
申请号：US18239337
申请日：2023-08-29
发明人： Neil Buckley , Dan Belmont , Bryan Hauser , Myoung Goo Kim , Kumar Kannan
IPC分类号： C07D213/803
CPC分类号： C07D213/803
摘要： The invention provides methods of chemical synthesis of the pharmacological agent 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate, also called CV-8972. The methods entail formation of a free base form of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethanol, also called CV-8814, as intermediate without producing a salt form of CV-8814.
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公开(公告)号：US12108979B2
公开(公告)日：2024-10-08
申请号：US18411460
申请日：2024-01-12
发明人： David Townley
CPC分类号： A61B18/148 , A61B2018/00327 , A61B2018/00434 , A61B2018/00583 , A61B2018/1467
摘要： The invention generally relates to systems and methods for improving sleep by treating at least one of rhinitis, congestion, and/or rhinorrhea to thereby reduce or eliminate symptoms associated therewith, including, but not limited to, nasal congestion, coughing, sneezing, and nasal or throat irritation and itching.
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公开(公告)号：US12096974B1
公开(公告)日：2024-09-24
申请号：US18647929
申请日：2024-04-26
发明人： David Townley
CPC分类号： A61B18/148 , A61B2018/00327 , A61B2018/00434 , A61B2018/00583 , A61B2018/1467
摘要： The invention generally relates to systems and methods for improving sleep by treating at least one of rhinitis, congestion, and/or rhinorhea to thereby reduce or eliminate symptoms associated therewith, including, but not limited to, nasal congestion, coughing, sneezing, and nasal or throat irritation and itching.
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公开(公告)号：US12084646B2
公开(公告)日：2024-09-10
申请号：US17673443
申请日：2022-02-16
申请人： FLASKWORKS, LLC
发明人： Shashi K. Murthy , Andrew Kozbial
IPC分类号： C12M1/00 , A01N1/02 , C12M1/04 , C12M1/12 , C12M1/26 , C12M1/34 , C12M1/36 , C12M1/42 , C12M3/00 , C12N5/00 , C12N5/0783 , C12N5/0784 , A61K35/17
CPC分类号： C12M23/58 , A01N1/0221 , C12M23/24 , C12M23/48 , C12M29/00 , C12M29/10 , C12M29/14 , C12M33/12 , C12M35/08 , C12M37/04 , C12M41/14 , C12M41/34 , C12M41/48 , C12M45/22 , C12N5/00 , C12N5/0637 , C12N5/0638 , C12N5/0639 , A61K35/17 , C12N5/0636 , C12N2501/998 , C12N2502/1121 , C12N2502/1157
摘要： Cell culture systems and methods provide improved immunotherapeutic product manufacturing with greater scalability, flexibility, and automation. Cell culture systems are configured with interchangeable cartridges, allowing versatility and scalability. Systems are configured to have multiple connected cell culture chambers, which allows parallel processing of different types of cells. Gas-impermeable cell culture chambers and methods for generating cells in closed systems prevent contamination and user error. Methods for recycling cell culture medium provide additional efficiencies.
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公开(公告)号：US12082872B2
公开(公告)日：2024-09-10
申请号：US17312495
申请日：2019-12-06
发明人： David Townley , Brian Shields
IPC分类号： A61B18/14 , A61B34/10 , A61B34/20 , A61N1/05 , A61N1/40 , G06T7/00 , A61B17/00 , A61B18/00 , A61B18/02 , A61B18/12 , A61B18/18 , A61B18/20 , A61B90/00 , A61B90/94
CPC分类号： A61B18/1485 , A61B18/14 , A61B34/10 , A61B34/20 , A61N1/0546 , A61N1/403 , G06T7/0012 , A61B2017/00199 , A61B2017/00292 , A61B2017/00424 , A61B2017/00867 , A61B2018/0016 , A61B2018/00166 , A61B2018/00214 , A61B2018/00303 , A61B2018/00327 , A61B2018/00434 , A61B2018/00577 , A61B2018/00654 , A61B2018/00815 , A61B2018/00821 , A61B2018/00875 , A61B2018/00922 , A61B2018/00946 , A61B18/02 , A61B18/1206 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/144 , A61B2018/1467 , A61B2018/1475 , A61B2018/1823 , A61B18/20 , A61B2034/102 , A61B2090/3735 , A61B2090/3762 , A61B2090/378 , A61B90/94 , A61B2218/007
摘要： The invention generally relates to systems and methods for therapeutically modulating nerves in or associated with a nasal region of a patient for the treatment of a rhinosinusitis condition.
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公开(公告)号：US12073469B2
公开(公告)日：2024-08-27
申请号：US18238360
申请日：2023-08-25
发明人： William Peterffy , Emerito Medalla , Sanjoy Ghosh , Yatharth Manuja , Konstantine Smaguine , Yakov Gorodnitsky
CPC分类号： G06Q40/06 , G06F16/2379 , G06Q40/04
摘要： A computer implemented method of evaluating market participants' stock portfolios and distributing actionable environmental, social and governance (ESG) stock data over a network to multiple remote market participant terminals allowing market participants to easily rebalance their portfolios so that their investments align with their personal values or social tolerances. The method comprises receiving from multiple sources non-standardized electronic ESG data for a plurality of securities, mapping, scaling and normalizing the data to present a final impact score that the market participant can act upon.
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公开(公告)号：US12071605B2
公开(公告)日：2024-08-27
申请号：US17886085
申请日：2022-08-11
申请人： FLASKWORKS, LLC
发明人： Shashi K. Murthy , Andrew Kozbial
IPC分类号： C12M1/00 , A01N1/02 , C12M1/04 , C12M1/12 , C12M1/26 , C12M1/34 , C12M1/36 , C12M1/42 , C12M3/00 , C12N5/00 , C12N5/0783 , C12N5/0784 , A61K35/17
CPC分类号： C12M23/58 , A01N1/0221 , C12M23/24 , C12M23/48 , C12M29/00 , C12M29/10 , C12M29/14 , C12M33/12 , C12M35/08 , C12M37/04 , C12M41/14 , C12M41/34 , C12M41/48 , C12M45/22 , C12N5/00 , C12N5/0637 , C12N5/0638 , C12N5/0639 , A61K35/17 , C12N5/0636 , C12N2501/998 , C12N2502/1121 , C12N2502/1157
摘要： Cell culture systems and methods provide improved immunotherapeutic product manufacturing with greater scalability, flexibility, and automation. Cell culture systems are configured with interchangeable cartridges, allowing versatility and scalability. Systems are configured to have multiple connected cell culture chambers, which allows parallel processing of different types of cells. Gas-impermeable cell culture chambers and methods for generating cells in closed systems prevent contamination and user error. Methods for recycling cell culture medium provide additional efficiencies.
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公开(公告)号：USD1030849S1
公开(公告)日：2024-06-11
申请号：US29713849
申请日：2019-11-19
设计人： Yunchao Fan , Junsheng Li , Tongbing Huang
摘要： FIG. 1 is a front view of eye-tracking glasses, showing our new design;
FIG. 2 is a rear view thereof;
FIG. 3 is a left view thereof;
FIG. 4 is a right view thereof;
FIG. 5 is a top view thereof;
FIG. 6 is a bottom view thereof;
FIG. 7 is a perspective view thereof; and,
FIG. 8 is another perspective view thereof.
The broken lines shown in the figures depict portions of the eye-tracking glasses that form no part of the claimed design.-
10.发明授权公开(公告)号：US11993617B2
公开(公告)日：2024-05-28
申请号：US17071612
申请日：2020-10-15
发明人： Zhihong Dai , Yongjun Wu , Jin Qiao , Chi Yuen Raymond Kwong , Chuanjun Xia
IPC分类号： H10K85/30 , C07F3/06 , C07F15/00 , H10K50/11 , H10K101/10
CPC分类号： C07F3/06 , C07F15/0033 , H10K85/342 , H10K50/11 , H10K2101/10
摘要： Provided is an organic light-emitting material having an ancillary ligand with partially fluorinated substituents. The organic light-emitting material is a metal complex having a diketone ancillary ligand with partially fluorinated substituents and may be used as a light-emitting material in an organic electroluminescent device. These new types of metal complex can fine-tune the emission wavelength more effectively, reduce voltage, improve efficiency, prolong lifetimes, and provide better device performance. Further provided are an organic electroluminescent device and a compound formulation.
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