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公开(公告)号：US10777724B2
公开(公告)日：2020-09-15
申请号：US16049205
申请日：2018-07-30
申请人： GAS TECHNOLOGY INSTITUTE , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, ON BEHALF OF ITS MERCED CAMPUS , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, ON BEHALF OF ITS BERKELEY CAMPUS
IPC分类号： H01L35/02 , H01L31/046 , H02S40/22 , H02S40/44 , F24S23/70
摘要： A hybrid solar system including a hybrid solar collector using non-imaging optics and photovoltaic components and a heat transfer and storage system in thermal communication with the hybrid solar collector, the heat transfer and storage system using particle laden gas as thermal media to simultaneously generate and store electricity and high temperature dispatchable heat.
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公开(公告)号：US20190249172A1
公开(公告)日：2019-08-15
申请号：US16077982
申请日：2017-02-16
CPC分类号： C12N15/11 , C07K14/4747 , C12N9/22 , C12N15/10 , C12N15/102 , C12N2310/20 , C12N2800/80
摘要： The present disclosure provides methods for gene editing in stem cells. The methods generally involve modifying the stem cells by increasing the level of an apoptosis regulator in the stem cells; and introducing into the modified stem cells a genome editing composition.
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公开(公告)号：US20240063340A1
公开(公告)日：2024-02-22
申请号：US17642057
申请日：2020-09-10
发明人： Stacia Keller , Umesh K. Mishra , Shubhra Pasayat , Chirag Gupta
IPC分类号： H01L33/32 , H01L33/16 , H01L33/12 , H01L25/075 , H01L33/20
CPC分类号： H01L33/32 , H01L33/16 , H01L33/12 , H01L25/0753 , H01L33/20
摘要： The present disclosure describes porous GaN layers and/or compliant substrates used to enable relaxation of previously strained top layers and the deposition of relaxed or partially relaxed on top. Relaxed In GaN layers are fabricated without generation of crystal defects, which can serve as base layers for high performance long wavelength light emitting devices (LEDs, lasers) solar cells, or strain engineered transistors. Similarly, relaxed AlGaN layers can serve as base layers for high performance short wavelength UV light emitting devices (LEDs, lasers) solar cells, or wide bandgap transistors.
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公开(公告)号：US20190256824A1
公开(公告)日：2019-08-22
申请号：US16096784
申请日：2017-05-01
发明人： Hooman Hefzi , Nathan E. Lewis
摘要： Provided are mammalian cells devoid of lactate dehydrogenase activity.
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公开(公告)号：US20200269323A1
公开(公告)日：2020-08-27
申请号：US16305387
申请日：2017-05-23
发明人： Peidong Yang , Fan Cui , Letian Dou , Zhiqiang Niu
IPC分类号： B22F9/24 , B22F1/00 , H01L31/0224 , H01L31/18
摘要： Provided are methods for synthesizing metal nanowires in solution using an organic reducing agent. A reaction mixture can be provided in solution with a metal salt, the organic reducing agent, and a solvent, where the solvent includes a surface ligand or consists of a surface ligand. The organic reducing agent, such as benzoin, can be decomposed in the reaction mixture to form organic free radicals that reduce metal ions of the metal salt into metal. The surface ligand of the solvent can coordinate with the metal in a manner so that metal nanowires are formed in solution. The diameter and morphology of the nanowires, reaction speed, reaction yield, and other features may be tunable by adjusting parameters such as reaction temperature and chemistry of the reducing agent.
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6.发明公开公开(公告)号：US20240364560A1
公开(公告)日：2024-10-31
申请号：US18647742
申请日：2024-04-26
发明人： Shijia Pan , Yue Zhang , Zhizhang Hu
IPC分类号： H04L12/28 , G05B15/02 , G05B19/418
CPC分类号： H04L12/2827 , G05B15/02 , G05B19/418 , G05B2219/2642
摘要： Cross-modal association (CMA), such as cross-modal signal segment association, is described for associating structural vibration and wearable sensors. This includes an Association Discovery Temporal Convolutional Network (AD-TCN) that determines the amount of shared context between a structural vibration sensor and associated wearable sensor candidates from the parameters of the trained model. CMA achieves improvements in AUC values, F1 scores, and accuracy over relevant baselines. In at least one embodiment, the vibration sensor is associated with a physical structure, the wearable sensor is associated with a person, and the modules estimate association between vibration sensor signals and a person who induces the vibration sensor signals interior to the structure.
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公开(公告)号：US20240360567A1
公开(公告)日：2024-10-31
申请号：US18592870
申请日：2024-03-01
发明人： Xin Chen , Erika Callagon La Plante , Gaurav Sant , David Jassby , Dante Adam Simonetti , Thomas Traynor
CPC分类号： C25B1/20 , C25B9/19 , C25B9/30 , C25B11/03 , C25B11/046 , C25B13/08 , C25B15/081
摘要： A method for producing one or more hydroxide solids includes providing a catholyte comprising an electrolyte solution; contacting the catholyte with an electroactive mesh cathode to electrolytically generate hydroxide ions, thereby precipitating the one or more hydroxide solid(s); and removing the one or more hydroxide solids from the surface of the mesh where they may deposit.
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公开(公告)号：US12131424B2
公开(公告)日：2024-10-29
申请号：US18318661
申请日：2023-05-16
CPC分类号： G06T17/20 , A61B5/341 , A61B5/361 , A61B5/6823 , A61B5/7246 , A61B5/7278 , A61B5/7445 , G06T5/20 , G06T7/0012 , G06T2207/10081 , G06T2207/10088 , G06T2207/10116 , G06T2207/10121 , G06T2207/30048
摘要： A system for computational localization of fibrillation sources is provided. In some implementations, the system performs operations comprising generating a representation of electrical activation of a patient's heart and comparing, based on correlation, the generated representation against one or more stored representations of hearts to identify at least one matched representation of a heart. The operations can further comprise generating, based on the at least one matched representation, a computational model for the patient's heart, wherein the computational model includes an illustration of one or more fibrillation sources in the patient's heart. Additionally, the operations can comprise displaying, via a user interface, at least a portion of the computational model. Related systems, methods, and articles of manufacture are also described.
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公开(公告)号：US20240352535A1
公开(公告)日：2024-10-24
申请号：US18684427
申请日：2022-08-17
发明人： Paul C. BOUTROS , Michael FRASER
IPC分类号： C12Q1/6886
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/154 , C12Q2600/156 , C12Q2600/158
摘要： Disclosed herein are methods and compositions for treatment, prognosis, and diagnosis of cancer, including prostate cancer. Aspects of the disclosure are directed to methods for a subject having prostate cancer determined to have ZNRF3 genomic loss, reduced ZNRF3 expression, and/or increased ZNRF3 methylation. Also disclosed are methods for analysis of tumor DNA for ZNRF3 copy number status, expression, and/or methylation, as well as compositions and kits useful for such analysis.
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公开(公告)号：US20240352517A1
公开(公告)日：2024-10-24
申请号：US18637154
申请日：2024-04-16
IPC分类号： C12Q1/6874 , C12Q1/54 , C12Q1/6869 , C25B3/29 , G01N27/327 , G01N27/416 , G01N33/487
CPC分类号： C12Q1/6874 , C12Q1/54 , C12Q1/6869 , C25B3/29 , G01N27/3278 , G01N27/4166 , G01N33/48721
摘要： Devices and methods that can detect and control an individual polymer in a mixture is acted upon by another compound, for example, an enzyme, in a nanopore are provided. The devices and methods also determine (˜>50 Hz) the nucleotide base sequence of a polynucleotide under feedback control or using signals generated by the interactions between the polynucleotide and the nanopore. The invention is of particular use in the fields of molecular biology, structural biology, cell biology, molecular switches, molecular circuits, and molecular computational devices, and the manufacture thereof.
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